Charge Transfer Kinetics in Thin-Film Voltammetry. Theoretical Study under Conditions of Square-Wave Voltammetry

2004 ◽  
Vol 108 (36) ◽  
pp. 13719-13725 ◽  
Author(s):  
Valentin Mirčeski
Keyword(s):  
Thin Film ◽  
Charge Transfer ◽  
Square Wave Voltammetry ◽  
Theoretical Study ◽  
Square Wave ◽  
Wave Voltammetry

scholarly journals Protein-film voltammetry: A theoretical study of the temperature effect using square-wave voltammetry

2008 ◽  
Vol 137 (1) ◽  
pp. 49-55 ◽  
Author(s):  
Rubin Gulaboski ◽  
Milivoj Lovrić ◽  
Valentin Mirčeski ◽  
Ivan Bogeski ◽  
Markus Hoth
Keyword(s):  
Temperature Effect ◽  
Square Wave Voltammetry ◽  
Theoretical Study ◽  
Protein Film ◽  
Square Wave ◽  
Protein Film Voltammetry ◽  
Wave Voltammetry

scholarly journals Portable Chronic Alcohol Consumption Monitor in Human Sweat through Square-Wave Voltammetry

2017 ◽  
Vol 23 (2) ◽  
pp. 144-153 ◽  
Author(s):  
David Kinnamon ◽  
Sriram Muthukumar ◽  
Anjan Panneer Selvam ◽  
Shalini Prasad
Keyword(s):  
Charge Transfer ◽  
Alcohol Consumption ◽  
Square Wave Voltammetry ◽  
The United States ◽  
Current Response ◽  
Chronic Alcohol ◽  
Chronic Alcohol Consumption ◽  
Square Wave ◽  
Human Sweat ◽  
Wave Voltammetry

Chronic alcohol consumption is a significant financial and physical burden in the United States each year. Alcohol consumption monitors focus on establishing a state of intoxication, not assessing a user’s health risks as a function of consumed alcohol. This work demonstrates a biosensor for a chronic alcohol consumption monitor through the electrochemical detection of ethyl glucuronide (EtG) in human sweat using square-wave voltammetry (SWV). A novel affinity assay was demonstrated in which monoclonal antibodies were chemically coabsorbed onto a gold electrode surface in parallel with thiolated charge transfer molecule. Concentration-dependent EtG binding was detected by measuring a reduction in the charge transfer of the sensor, manifesting as a current response during SWV measurement. A companion compact electronic reader was constructed, demonstrating comparable sensitivity to a conventional lab instrument. Both tools demonstrated a limit of detection of 0.1 µg/L and a linear dynamic range of 0.1–100 µg/L corresponding to the physiologically relevant range of EtG expression in human sweat. This device can address the need for a chronic alcohol consumption monitor toward establishing a user’s long-term consumption habits to assess the risk of developing specific diseases and conditions associated with regular alcohol consumption, through integration with existing technologies.

Sign in / Sign up

Export Citation Format

Share Document