scholarly journals Phase Behavior of Model Lipid Bilayers†

2005 ◽  
Vol 109 (14) ◽  
pp. 6553-6563 ◽  
Author(s):  
Marieke Kranenburg ◽  
Berend Smit
Keyword(s):  
Phase Behavior ◽  
Lipid Bilayers

scholarly journals Phase behavior and domain size in sphingomyelin-containing lipid bilayers

2013 ◽  
Vol 1828 (4) ◽  
pp. 1302-1313 ◽  
Author(s):  
Robin S. Petruzielo ◽  
Frederick A. Heberle ◽  
Paul Drazba ◽  
John Katsaras ◽  
Gerald W. Feigenson
Keyword(s):  
Phase Behavior ◽  
Lipid Bilayers ◽  
Domain Size

scholarly journals Understanding the Phase Behavior of Coarse-Grained Model Lipid Bilayers through Computational Calorimetry

2012 ◽  
Vol 116 (5) ◽  
pp. 1551-1569 ◽  
Author(s):  
Jocelyn M. Rodgers ◽  
Jesper Sørensen ◽  
Frédérick J.-M. de Meyer ◽  
Birgit Schiøtt ◽  
Berend Smit
Keyword(s):  
Phase Behavior ◽  
Lipid Bilayers ◽  
Coarse Grained ◽  
Coarse Grained Model

Contrasting Effects of a Rigid Core and an Alkyl Chain in nCB on the Phase Behavior of Lipid Bilayers

Langmuir ◽  
2016 ◽  
Vol 32 (23) ◽  
pp. 5966-5972 ◽  
Author(s):  
Hatsuho Usuda ◽  
Mafumi Hishida ◽  
Yasuhisa Yamamura ◽  
Kazuya Saito
Keyword(s):  
Phase Behavior ◽  
Lipid Bilayers ◽  
Alkyl Chain ◽  
Rigid Core

scholarly journals Membrane Protein Structures in Lipid Bilayers; Small-Angle Neutron Scattering With Contrast-Matched Bicontinuous Cubic Phases

2021 ◽  
Vol 8 ◽  
Author(s):  
Charlotte E. Conn ◽  
Liliana de Campo ◽  
Andrew E. Whitten ◽  
Christopher J. Garvey ◽  
Anwen M. Krause-Heuer ◽  
...  
Keyword(s):  
Membrane Protein ◽  
Neutron Scattering ◽  
Phase Behavior ◽  
Lipid Bilayers ◽  
Small Angle ◽  
Small Angle Neutron Scattering ◽  
Protein Structures ◽  
Bicontinuous Cubic ◽  
Contrast Matching ◽  
Detergent Micelles

This perspective describes advances in determining membrane protein structures in lipid bilayers using small-angle neutron scattering (SANS). Differentially labeled detergents with a homogeneous scattering length density facilitate contrast matching of detergent micelles; this has previously been used successfully to obtain the structures of membrane proteins. However, detergent micelles do not mimic the lipid bilayer environment of the cell membrane in vivo. Deuterated vesicles can be used to obtain the radius of gyration of membrane proteins, but protein-protein interference effects within the vesicles severely limits this method such that the protein structure cannot be modeled. We show herein that different membrane protein conformations can be distinguished within the lipid bilayer of the bicontinuous cubic phase using contrast-matching. Time-resolved studies performed using SANS illustrate the complex phase behavior in lyotropic liquid crystalline systems and emphasize the importance of this development. We believe that studying membrane protein structures and phase behavior in contrast-matched lipid bilayers will advance both biological and pharmaceutical applications of membrane-associated proteins, biosensors and food science.

scholarly journals Accumulation of styrene oligomers alters lipid membrane phase order and miscibility

2021 ◽  
Vol 118 (4) ◽  
pp. e2016037118
Author(s):  
Mattia I. Morandi ◽  
Monika Kluzek ◽  
Jean Wolff ◽  
André Schroder ◽  
Fabrice Thalmann ◽  
...  
Keyword(s):  
Phase Behavior ◽  
Lipid Bilayers ◽  
Lipid Membranes ◽  
Lipid Membrane ◽  
Spatial Modulation ◽  
Plastic Materials ◽  
Polymeric Species ◽  
Cell Components ◽  
Membrane Models ◽  
Membrane Mechanical Properties

Growth of plastic waste in the natural environment, and in particular in the oceans, has raised the accumulation of polystyrene and other polymeric species in eukyarotic cells to the level of a credible and systemic threat. Oligomers, the smallest products of polymer degradation or incomplete polymerization reactions, are the first species to leach out of macroscopic or nanoscopic plastic materials. However, the fundamental mechanisms of interaction between oligomers and polymers with the different cell components are yet to be elucidated. Simulations performed on lipid bilayers showed changes in membrane mechanical properties induced by polystyrene, but experimental results performed on cell membranes or on cell membrane models are still missing. We focus here on understanding how embedded styrene oligomers affect the phase behavior of model membranes using a combination of scattering, fluorescence, and calorimetric techniques. Our results show that styrene oligomers disrupt the phase behavior of lipid membranes, modifying the thermodynamics of the transition through a spatial modulation of lipid composition.

scholarly journals Phase behavior of pure lipid bilayers with mismatch interactions

1992 ◽  
Vol 45 (10) ◽  
pp. 7560-7567 ◽  
Author(s):  
Zhengping Zhang ◽  
Mohamed Laradji ◽  
Hong Guo ◽  
O. G. Mouritsen ◽  
M. J. Zuckermann
Keyword(s):  
Phase Behavior ◽  
Lipid Bilayers
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