Water penetration and phase behavior of surfactant gel phases and lipid bilayers

1990 ◽  
Vol 94 (18) ◽  
pp. 7265-7271 ◽  
Author(s):  
A. Muga ◽  
Hector L. Casal
2013 ◽  
Vol 1828 (4) ◽  
pp. 1302-1313 ◽  
Author(s):  
Robin S. Petruzielo ◽  
Frederick A. Heberle ◽  
Paul Drazba ◽  
John Katsaras ◽  
Gerald W. Feigenson

2005 ◽  
Vol 109 (14) ◽  
pp. 6553-6563 ◽  
Author(s):  
Marieke Kranenburg ◽  
Berend Smit

2012 ◽  
Vol 116 (5) ◽  
pp. 1551-1569 ◽  
Author(s):  
Jocelyn M. Rodgers ◽  
Jesper Sørensen ◽  
Frédérick J.-M. de Meyer ◽  
Birgit Schiøtt ◽  
Berend Smit

Langmuir ◽  
2016 ◽  
Vol 32 (23) ◽  
pp. 5966-5972 ◽  
Author(s):  
Hatsuho Usuda ◽  
Mafumi Hishida ◽  
Yasuhisa Yamamura ◽  
Kazuya Saito

2013 ◽  
Vol 1828 (2) ◽  
pp. 510-517 ◽  
Author(s):  
Elena Conte ◽  
Francesco Maria Megli ◽  
Himanshu Khandelia ◽  
Gunnar Jeschke ◽  
Enrica Bordignon

2021 ◽  
Vol 8 ◽  
Author(s):  
Charlotte E. Conn ◽  
Liliana de Campo ◽  
Andrew E. Whitten ◽  
Christopher J. Garvey ◽  
Anwen M. Krause-Heuer ◽  
...  

This perspective describes advances in determining membrane protein structures in lipid bilayers using small-angle neutron scattering (SANS). Differentially labeled detergents with a homogeneous scattering length density facilitate contrast matching of detergent micelles; this has previously been used successfully to obtain the structures of membrane proteins. However, detergent micelles do not mimic the lipid bilayer environment of the cell membrane in vivo. Deuterated vesicles can be used to obtain the radius of gyration of membrane proteins, but protein-protein interference effects within the vesicles severely limits this method such that the protein structure cannot be modeled. We show herein that different membrane protein conformations can be distinguished within the lipid bilayer of the bicontinuous cubic phase using contrast-matching. Time-resolved studies performed using SANS illustrate the complex phase behavior in lyotropic liquid crystalline systems and emphasize the importance of this development. We believe that studying membrane protein structures and phase behavior in contrast-matched lipid bilayers will advance both biological and pharmaceutical applications of membrane-associated proteins, biosensors and food science.


2021 ◽  
Vol 118 (4) ◽  
pp. e2016037118
Author(s):  
Mattia I. Morandi ◽  
Monika Kluzek ◽  
Jean Wolff ◽  
André Schroder ◽  
Fabrice Thalmann ◽  
...  

Growth of plastic waste in the natural environment, and in particular in the oceans, has raised the accumulation of polystyrene and other polymeric species in eukyarotic cells to the level of a credible and systemic threat. Oligomers, the smallest products of polymer degradation or incomplete polymerization reactions, are the first species to leach out of macroscopic or nanoscopic plastic materials. However, the fundamental mechanisms of interaction between oligomers and polymers with the different cell components are yet to be elucidated. Simulations performed on lipid bilayers showed changes in membrane mechanical properties induced by polystyrene, but experimental results performed on cell membranes or on cell membrane models are still missing. We focus here on understanding how embedded styrene oligomers affect the phase behavior of model membranes using a combination of scattering, fluorescence, and calorimetric techniques. Our results show that styrene oligomers disrupt the phase behavior of lipid membranes, modifying the thermodynamics of the transition through a spatial modulation of lipid composition.


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