Intramolecular Catalysis of Thiol Ester Hydrolysis by a Tertiary Amine and a Carboxylate

1997 ◽  
Vol 62 (14) ◽  
pp. 4816-4820 ◽  
Author(s):  
R. S. Brown ◽  
Ahmed Aman
Keyword(s):  
Tertiary Amine ◽  
Ester Hydrolysis ◽  
Thiol Ester ◽  
Intramolecular Catalysis

Exploration of in vitro pro-drug activation and futile cycling by glutathione S-transferases: thiol ester hydrolysis and inhibitor maturation

2003 ◽  
Vol 414 (2) ◽  
pp. 303-311 ◽  
Author(s):  
Catherine Ibarra ◽  
Mark P Grillo ◽  
Mario Lo Bello ◽  
Marzia Nucettelli ◽  
Theo K Bammler ◽  
...  
Keyword(s):  
Ester Hydrolysis ◽  
Thiol Ester ◽  
Glutathione S Transferases ◽  
Futile Cycling ◽  
Drug Activation

scholarly journals Incorporation of a single His residue by rational design enables thiol-ester hydrolysis by human glutathione transferase A1-1

2004 ◽  
Vol 101 (36) ◽  
pp. 13163-13167 ◽  
Author(s):  
S. Hederos ◽  
K. S. Broo ◽  
E. Jakobsson ◽  
G. J. Kleywegt ◽  
B. Mannervik ◽  
...  
Keyword(s):  
Rational Design ◽  
Glutathione Transferase ◽  
Ester Hydrolysis ◽  
Thiol Ester

Kinetic and Theoretical Studies on the Mechanism of Intramolecular Catalysis in Phenyl Ester Hydrolysis

2006 ◽  
Vol 71 (20) ◽  
pp. 7650-7656 ◽  
Author(s):  
Gabriel O. Andrés ◽  
Adriana B. Pierini ◽  
Rita H. de Rossi
Keyword(s):  
Ester Hydrolysis ◽  
Theoretical Studies ◽  
Phenyl Ester ◽  
Intramolecular Catalysis

Thiol Ester Hydrolysis Catalyzed by GlutathioneS-Transferase A1-1†

Biochemistry ◽  
1998 ◽  
Vol 37 (42) ◽  
pp. 14948-14957 ◽  
Author(s):  
Eric C. Dietze ◽  
Mark P. Grillo ◽  
Thomas Kalhorn ◽  
Brenda S. Nieslanik ◽  
Claudia M. Jochheim ◽  
...  
Keyword(s):  
Ester Hydrolysis ◽  
Thiol Ester

The kinetics and mechanism of metal ion promoted thiol ester hydrolysis

1969 ◽  
Vol 10 (24) ◽  
pp. 1991-1994 ◽  
Author(s):  
D.P.N. Satchell ◽  
I.I. Secemski
Keyword(s):  
Metal Ion ◽  
Ester Hydrolysis ◽  
Kinetics And Mechanism ◽  
Thiol Ester
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