Direct Synthesis of Polysubstituted Quinoline Derivatives by InBr3-Promoted Dimerization of 2-Ethynylaniline Derivatives

2006 ◽  
Vol 71 (9) ◽  
pp. 3653-3655 ◽  
Author(s):  
Norio Sakai ◽  
Kimiyoshi Annaka ◽  
Takeo Konakahara
Keyword(s):  
Direct Synthesis ◽  
Quinoline Derivatives

Direct Synthesis of 6H-Chromeno[3,4-b]quinolin-6-ol Derivatives from Substituted 3-Nitro-2H-chromenes and 2-Nitrobenzaldehydes Mediated by Fe/AcOH System

Synthesis ◽  
2017 ◽  
Vol 50 (06) ◽  
pp. 1350-1358 ◽  
Author(s):  
Cunde Wang ◽  
Xushun Qing ◽  
Ting Wang ◽  
Chenlu Dai ◽  
Zhenjie Su
Keyword(s):  
Acetic Acid ◽  
Nucleophilic Addition ◽  
Aldol Condensation ◽  
Direct Synthesis ◽  
Reductive Cyclization ◽  
Quinoline Derivatives ◽  
Acid System ◽  
X Ray ◽  
X Ray Crystallography ◽  
Sequential Reduction

An efficient iron/acetic acid system-mediated reductive cyclization reaction of substituted 2-aryl-3-nitro-2H-chromenes with substituted 2-nitrobenzaldehydes for the synthesis of 6-aryl-6H-chromeno[3,4-b]quinolines was developed. This reaction involves the sequential reduction, hydrolysis, aldol condensation, intramolecular addition, and the nucleophilic addition of substituted 2-aryl-3-nitro-2H-chromenes with substituted 2-nitrobenzaldehydes to give the corresponding 6H-chromeno[3,4-b]quinolines. This transformation provides a straightforward synthetic protocol for constructing substituted 6H-chromeno[3,4-b]quinoline derivatives. The structures of three typical products were confirmed by X-ray crystallography.

scholarly journals A Novel Direct Synthesis of theN-Oxides of Quinoline Derivatives

1966 ◽  
Vol 39 (1) ◽  
pp. 195-195 ◽  
Author(s):  
Yusuf Ahmad ◽  
Shamim Ahmad Shamsi
Keyword(s):  
Direct Synthesis ◽  
Quinoline Derivatives

ChemInform Abstract: An Atom Economical Method for the Direct Synthesis of Quinoline Derivatives from Substituted O-Nitrotoluenes.

ChemInform ◽  
2015 ◽  
Vol 46 (27) ◽  
pp. no-no
Author(s):  
Guiyan Liu ◽  
Maocong Yi ◽  
Lu Liu ◽  
Jingjing Wang ◽  
Jianhui Wang
Keyword(s):  
Direct Synthesis ◽  
Quinoline Derivatives ◽  
Economical Method

An atom economical method for the direct synthesis of quinoline derivatives from substituted o-nitrotoluenes

2015 ◽  
Vol 51 (14) ◽  
pp. 2911-2914 ◽  
Author(s):  
Guiyan Liu ◽  
Maocong Yi ◽  
Lu Liu ◽  
Jingjing Wang ◽  
Jianhui Wang
Keyword(s):  
Direct Synthesis ◽  
Quinoline Derivatives ◽  
Reaction Conditions ◽  
One Pot ◽  
Economical Method ◽  
Substituted Quinolines ◽  
Acrylic Esters

A one-pot procedure for the preparation of substituted quinolines from substituted o-nitrotoluenes with electron-withdrawing groups and olefins (acrylic esters and acrylonitriles) using a cesium catalyst under mild reaction conditions is reported. The process involves a [2+4] cycloaddition mechanism.

Substituted Amides of Quinoline Derivatives: Preparation and Their Photosynthesis-inhibiting Activity

2006 ◽  
Author(s):  
Robert Musiol ◽  
Josef Jampilek ◽  
Katarina Kralova ◽  
Dominik Tabak ◽  
Barbara Podeszwa ◽  
...  
Keyword(s):  
Inhibiting Activity ◽  
Quinoline Derivatives
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