Three-Component One-Pot Total Syntheses of Glyantrypine, Fumiquinazoline F, and Fiscalin B Promoted by Microwave Irradiation†

2005 ◽  
Vol 70 (16) ◽  
pp. 6339-6345 ◽  
Author(s):  
Ji-Feng Liu ◽  
Ping Ye ◽  
Bailin Zhang ◽  
Grace Bi ◽  
Katie Sargent ◽  
...  
2005 ◽  
Vol 7 (15) ◽  
pp. 3363-3366 ◽  
Author(s):  
Ji-Feng Liu ◽  
Ping Ye ◽  
Kevin Sprague ◽  
Katie Sargent ◽  
Daniel Yohannes ◽  
...  

ChemInform ◽  
2005 ◽  
Vol 36 (51) ◽  
Author(s):  
Ji-Feng Liu ◽  
Ping Ye ◽  
Bailin Zhang ◽  
Grace Bi ◽  
Katie Sargent ◽  
...  

2020 ◽  
Author(s):  
Ikram BABA AHMED ◽  
Zahira KIBOU ◽  
Pilar VÁZQUEZ-TATO ◽  
Julio SEIJAS ◽  
Noureddine CHOUKCHOU-BRAHAM

1999 ◽  
Vol 23 (9) ◽  
pp. 574-575
Author(s):  
Firouz Matloubi Moghaddam ◽  
Mohammad Ghaffarzadeh ◽  
Seyed Hossein Abdi-Oskoui

An AICl3–ZnCl2 mixture supported on silica gel is found to be an efficient medium for the Fries rearrangement of acyloxybenzene or naphthalene derivatives in solvent-free conditions under microwave irradiation.


Synthesis ◽  
2021 ◽  
Author(s):  
Muhammad Syafiq Bin Shahari ◽  
Ahmad Junaid ◽  
Edward R. T. Tiekink ◽  
Anton V. Dolzhenko

A new method for the fast synthesis of diverse 4-aryl-6-cycloamino-1,3,5-triazin-2-amines was developed. The synthesis is performed under microwave irradiation in a one-pot manner from cyanoguanidine, aromatic aldehydes, and cyclic amines. Their three-component reaction in the presence of hydrochloric acid produced dihydrotriazines, which were then converted (without isolation) to the targeted compounds via aromatic dehydrogenation in the presence of alkali. The reaction tolerated various aromatic aldehydes (including heterocyclic) and cyclic amines. Crystal structures of two representative 4-aryl-6-morpholino-1,3,5-triazin-2-amines were established by X-ray crystallography. The results of preliminary biological screening identified potent antileukemic activity for 6-(3,4-dihydroisoquinolin-2(1<i>H</i>)-yl)-4-phenyl-1,3,5-triazin-2-amine.


2011 ◽  
Vol 29 (1) ◽  
pp. 109-117 ◽  
Author(s):  
Song Bai ◽  
Baoan Song ◽  
Pinaki S. Bhadury ◽  
Song Yang ◽  
Deyu Hu ◽  
...  

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