A Computational Study on Addition of Grignard Reagents to Carbonyl Compounds

2002 ◽  
Vol 67 (26) ◽  
pp. 9346-9353 ◽  
Author(s):  
Shoko Yamazaki ◽  
Shinichi Yamabe
Keyword(s):  
Carbonyl Compounds ◽  
Computational Study ◽  
Grignard Reagents

Recent Advances in the Synthesis of Enantiomerically Enriched Diaryl, Aryl Heteroaryl, and Diheteroaryl Alcohols through Addition of Organometallic Reagents to Carbonyl Compounds

Synthesis ◽  
2020 ◽  
Vol 52 (13) ◽  
pp. 1855-1873
Author(s):  
Senthil Narayanaperumal ◽  
Ricardo S. Schwab ◽  
Wystan K. O. Teixeira ◽  
Danilo Yano de Albuquerque
Keyword(s):  
Carbonyl Compounds ◽  
Building Blocks ◽  
Short Review ◽  
Biological Properties ◽  
Enantioselective Synthesis ◽  
Grignard Reagents ◽  
Organometallic Reagents ◽  
Important Family ◽  
Organolithium Reagents ◽  
Organozinc Reagents

Enantiomerically enriched diaryl, aryl heteroaryl, and dihetero­aryl alcohols are an important family of compounds known for their biological properties. Moreover, these molecules are highly privileged scaffolds used as building blocks for the synthesis of pharmaceutically relevant products. This short review provides background on the enantioselective arylation and heteroarylation of carbonyl compounds, as well as, the most significant improvements in this field with special emphasis on the application of organometallic reagents.1 Introduction2 Background on the Enantioselective Synthesis of Diaryl, Aryl Heteroaryl, and Diheteroaryl Alcohols3 Organozinc Reagents4 Organolithium Reagents5 Grignard Reagents6 Organoaluminum Reagents7 Organotitanium Reagents8 Organobismuth Reagents9 Miscellaneous10 Conclusion

ChemInform Abstract: Reaction of Grignard Reagents with Carbonyl Compounds under Continuous Flow Conditions.

ChemInform ◽  
2010 ◽  
Vol 41 (36) ◽  
pp. no-no
Author(s):  
E. Riva ◽  
S. Gagliardi ◽  
M. Martinelli ◽  
D. Passarella ◽  
D. Vigo ◽  
...  
Keyword(s):  
Carbonyl Compounds ◽  
Continuous Flow ◽  
Grignard Reagents ◽  
Flow Conditions

scholarly journals Catalytic Synthesis of Enantiopure Chiral Alcohols via Addition of Grignard Reagents to Carbonyl Compounds

ACS Catalysis ◽  
2016 ◽  
Vol 6 (3) ◽  
pp. 1952-1970 ◽  
Author(s):  
Juan F. Collados ◽  
Ricard Solà ◽  
Syuzanna R. Harutyunyan ◽  
Beatriz Maciá
Keyword(s):  
Carbonyl Compounds ◽  
Catalytic Synthesis ◽  
Grignard Reagents ◽  
Chiral Alcohols

ChemInform Abstract: Chiral Phosphine-Phosphite Ligands in the Enantioselective 1,4-Addition of Grignard Reagents to α,β-Unsaturated Carbonyl Compounds.

ChemInform ◽  
2011 ◽  
Vol 42 (49) ◽  
pp. no-no
Author(s):  
Qaseem Naeemi ◽  
Tobias Robert ◽  
Darius P. Kranz ◽  
Janna Velder ◽  
Hans-Guenther Schmalz
Keyword(s):  
Carbonyl Compounds ◽  
Grignard Reagents ◽  
Phosphite Ligands

Reactions of carborane grignard reagents with carbonyl compounds

1967 ◽  
Vol 16 (9) ◽  
pp. 1994-1996 ◽  
Author(s):  
L. I. Zakharkin ◽  
A. V. Grebennikov ◽  
A. V. Kazantsev ◽  
A. I. L'vov
Keyword(s):  
Carbonyl Compounds ◽  
Grignard Reagents
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