Solid-Phase Total Synthesis of Trunkamide A1

2001 ◽  
Vol 66 (23) ◽  
pp. 7568-7574 ◽  
Author(s):  
Josep M. Caba ◽  
Ignacio M. Rodriguez ◽  
Ignacio Manzanares ◽  
Ernest Giralt ◽  
Fernando Albericio
Keyword(s):  
Total Synthesis ◽  
Solid Phase

Solid-Phase Total Synthesis of Scytalidamide A

2003 ◽  
Vol 68 (23) ◽  
pp. 8774-8779 ◽  
Author(s):  
Wenxin Gu ◽  
Richard B. Silverman
Keyword(s):  
Total Synthesis ◽  
Solid Phase

Solid‐Phase Total Synthesis of Yaku'amide B Enabled by Traceless Staudinger Ligation

2020 ◽  
Vol 59 (11) ◽  
pp. 4564-4571 ◽  
Author(s):  
Hiroaki Itoh ◽  
Kensuke Miura ◽  
Koichi Kamiya ◽  
Tomoya Yamashita ◽  
Masayuki Inoue
Keyword(s):  
Total Synthesis ◽  
Solid Phase ◽  
Staudinger Ligation

A Solid-Phase Approach to the Phallotoxins:  Total Synthesis of [Ala7]-Phalloidin

2005 ◽  
Vol 70 (12) ◽  
pp. 4578-4584 ◽  
Author(s):  
Marc O. Anderson ◽  
Anang A. Shelat ◽  
R. Kiplin Guy
Keyword(s):  
Total Synthesis ◽  
Solid Phase ◽  
Phase Approach

Segment Solid-Phase Total Synthesis of the Anthelmintic Cyclooctadepsipeptides PF1022A and Emodepside

2012 ◽  
Vol 2012 (8) ◽  
pp. 1546-1553 ◽  
Author(s):  
Jürgen Scherkenbeck ◽  
Sebastian Lüttenberg ◽  
Monika Ludwig ◽  
Karin Brücher ◽  
Andreas Kotthaus
Keyword(s):  
Total Synthesis ◽  
Solid Phase

Facile Solid-Phase Synthesis of Sulfated Tyrosine-Containing Peptides: Total Synthesis of Human Big Gastrin-II and Cholecystokinin (CCK)-391,2

2001 ◽  
Vol 66 (1) ◽  
pp. 1-10 ◽  
Author(s):  
Kouki Kitagawa ◽  
Chikako Aida ◽  
Hidetoshi Fujiwara ◽  
Takeshi Yagami ◽  
Shiroh Futaki ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Phase Synthesis

Solid-Phase Total Synthesis of Daptomycin and Analogs

2015 ◽  
Vol 17 (3) ◽  
pp. 748-751 ◽  
Author(s):  
Chuda Raj Lohani ◽  
Robert Taylor ◽  
Michael Palmer ◽  
Scott D. Taylor
Keyword(s):  
Total Synthesis ◽  
Solid Phase

Studies Toward the Total Synthesis and Stereochemical Assignment of Microspinosamide

2015 ◽  
Vol 68 (12) ◽  
pp. 1885 ◽  
Author(s):  
Gajan Santhakumar ◽  
Richard J. Payne
Keyword(s):  
Total Synthesis ◽  
Natural Product ◽  
Solid Phase ◽  
Solid Phase Peptide Synthesis ◽  
Chemical Ligation ◽  
Stereochemical Assignment ◽  
Linear Peptide ◽  
Cyclic Depsipeptide ◽  
Peptide Thioester ◽  
Structural Differences

Efforts toward the total synthesis and stereochemical assignment of the cyclic depsipeptide natural product microspinosamide are described. A single diastereoisomer was targeted corresponding to the predicted structure of the natural product incorporating a (2S, 3R)-β-hydroxy-p-bromophenylalanine residue. Assembly was achieved through the initial synthesis of a cyclic depsipeptide and a linear peptide thioester fragment by solid-phase peptide synthesis, followed by fusion of the two fragments through a native chemical ligation–oxidation protocol. Extensive spectroscopic analysis showed structural differences to the isolated natural product, suggesting that a diastereoisomer of microspinosamide had been synthesised. This work lays the foundation for the future synthesis of the correct diastereoisomer.

Solid-Phase Chemistry in the Total Synthesis of Non-Peptidic Natural Products

ChemInform ◽  
2006 ◽  
Vol 37 (37) ◽  
Author(s):  
Pablo Cironi ◽  
Mercedes Alvarez ◽  
Fernando Albericio
Keyword(s):  
Natural Products ◽  
Total Synthesis ◽  
Solid Phase ◽  
Phase Chemistry ◽  
Solid Phase Chemistry
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