Molecular associations of acetylcholine with aromatic molecules in water. Nuclear magnetic resonance spectral evidence

1979 ◽  
Vol 44 (18) ◽  
pp. 3247-3252 ◽  
Author(s):  
M. J. Minch ◽  
John P. Sevenair ◽  
C. Henling
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Aromatic Molecules ◽  
Molecular Associations ◽  
Spectral Evidence ◽  
Nuclear Magnetic

FORMATION OF DIASTEREOISOMERIC ORTHOACETATES OF D-MANNOSE: N.M.R. SPECTRAL EVIDENCE

1963 ◽  
Vol 41 (2) ◽  
pp. 399-406 ◽  
Author(s):  
A. S. Perlin
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Acid Hydrolysis ◽  
Chemical Shifts ◽  
Isomer Ratio ◽  
Methyl Group ◽  
Major Isomer ◽  
Spectral Evidence ◽  
Ratio Data ◽  
Nuclear Magnetic

Diastereoisomeric 1,2-orthoacetates of D-mannose are formed under conditions of the Königs–Knorr synthesis. This is shown by the isolation of two crystalline isomers of β-D-mannose 1,2-(benzyl orthoacetate), and also by examination of the nuclear magnetic resonance (n.m.r.) spectra of several D-mannose orthoacetates. The diastereoisomers show notable differences in respective chemical shifts for the C-methyl and other protons and these variations, together with isomer-ratio data, suggest that the major isomer of a given pair possesses the configuration in which the C-methyl group is endo- and the OR group is exo-. On acid hydrolysis the orthoacetates yield mainly 2-O-acetyl-D-mannose, the structure of which is confirmed by n.m.r. spectral evidence.

Thiazoloisoquinolines. III. Structure and methylation of 2-hydroxythiazolo[4,5-c]- and -[5,4-c]isoquinolines

1968 ◽  
Vol 46 (5) ◽  
pp. 691-694 ◽  
Author(s):  
Catherine E. Hall ◽  
Alfred Taurins
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Methyl Iodide ◽  
Dimethyl Sulfate ◽  
The Other ◽  
Thiazole Ring ◽  
Spectral Evidence ◽  
Other Hand ◽  
Methylating Agents ◽  
Nuclear Magnetic

2-Hydroxythiazolo[4,5-c]isoquinoline (1) and 2-hydroxythiazolo[5,4-c]isoquinoline (2) were both found to exist predominantly in the lactam form (1b and 2b respectively) from infrared, nuclear magnetic resonance, and ultraviolet spectral evidence. Various methylating agents methylated compound 1 exclusively on the N-3 atom in the thiazole ring. Compound 2 on the other hand, gave a mixture of O-and N-3 methylated products with diazomethane and a mixture of N-1 and N-4 methylated products with either methyl iodide or dimethyl sulfate.

SOME BASE-CATALYZED CONDENSATIONS OF SYSTEMS OF THE FORM R1R2C=C(CN)2

1965 ◽  
Vol 43 (4) ◽  
pp. 772-782 ◽  
Author(s):  
Mary R. S. Weir ◽  
J. B. Hyne
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Proton Nuclear Magnetic Resonance ◽  
Reaction Pathways ◽  
Organic Bases ◽  
Condensation Products ◽  
Spectral Evidence ◽  
Nuclear Magnetic

We have investigated the condensations of the systems [Formula: see text] and CH3HC=C(CN)2 in the presence of organic bases. Proton nuclear magnetic resonance (n.m.r.) spectral evidence is presented in support of the suggested structures of the condensation products, and an attempt has been made to present diagrammatically the interrelation between these condensations and other known reaction pathways for condensations of this type.

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