General methods of alkaloid synthesis. Synthesis of the 5,10b-ethanophenanthridine Amaryllidaceae alkaloids. Stereoselective total synthesis of dl-elwesine (dihydrocrinine)

1972 ◽  
Vol 37 (7) ◽  
pp. 977-982 ◽  
Author(s):  
R. V. Stevens ◽  
Louis E. DuPree ◽  
Patricia L. Loewenstein
2000 ◽  
Vol 72 (9) ◽  
pp. 1773-1776 ◽  
Author(s):  
C.-K. Sha ◽  
S.-J. Huang ◽  
C.-M. Huang ◽  
A.-W. Hong ◽  
T.-H. Jeng

Hexahydro-1H-indol-3-one can be used as a building block for alkaloid synthesis. Radical and anionic cyclization approaches toward this useful structure were developed. Approaches toward total synthesis of montanine-type Amaryllidaceae alkaloids using hexahydro-1H-indol-3-one as a key intermediate were studied.


Heterocycles ◽  
1985 ◽  
Vol 23 (12) ◽  
pp. 3033 ◽  
Author(s):  
Ignacio H. Sánchez ◽  
Mar誕 Isabel Larraza ◽  
Irma Rojas ◽  
Francisco Bre紡 ◽  
Humberto J. Flores ◽  
...  

2015 ◽  
Vol 51 (92) ◽  
pp. 16450-16467 ◽  
Author(s):  
Amit Kumar Chattopadhyay ◽  
Stephen Hanessian

Among many other strategies, the enaminone approach is an important strategy to construct and diversify the azacyclic core in various alkaloids syntheses. In this brief review we discuss the application of cyclic enaminones as building blocks, as well as potential intermediates in the total synthesis of selected alkaloids.


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