Effect of added dimethyl sulfoxide on the alkaline hydrolysis of p-nitroacetanilide

1974 ◽  
Vol 39 (14) ◽  
pp. 2108-2110 ◽  
Author(s):  
R. M. Pollack
Keyword(s):  
Dimethyl Sulfoxide ◽  
Alkaline Hydrolysis ◽  
Hydrolysis Of

Solvent Effect of Dimethyl Sulfoxide on Alkaline Hydrolysis of Amide

1974 ◽  
Vol 22 (4) ◽  
pp. 864-870 ◽  
Author(s):  
ITARU KOJO ◽  
SHOJI AWAZU ◽  
MANABU HANANO
Keyword(s):  
Solvent Effect ◽  
Dimethyl Sulfoxide ◽  
Alkaline Hydrolysis ◽  
Hydrolysis Of

Alkaline hydrolysis of dicarboxylic esters in aqueous dimethyl sulfoxide

1967 ◽  
Vol 8 (52) ◽  
pp. 5275-5280 ◽  
Author(s):  
N. Venkatasubramanian ◽  
G.Venkoba Rao
Keyword(s):  
Dimethyl Sulfoxide ◽  
Alkaline Hydrolysis ◽  
Hydrolysis Of

Influence of medium on alkaline hydrolysis of succinic acid monomethyl and monopropyl esters

1980 ◽  
Vol 45 (11) ◽  
pp. 2873-2882
Author(s):  
Vladislav Holba ◽  
Ján Benko
Keyword(s):  
Succinic Acid ◽  
Kinetic Parameters ◽  
Alkaline Hydrolysis ◽  
Specific Interactions ◽  
Nonaqueous Media ◽  
The Media ◽  
Kinetics Of ◽  
Hydrolysis Of

The kinetics of alkaline hydrolysis of succinic acid monomethyl and monopropyl esters were studied in mixed aqueous-nonaqueous media at various temperatures and ionic strengths. The results of measurements are discussed in terms of electrostatic and specific interactions between the reactants and other components of the reaction mixture. The kinetic parameters in the media under study are related to the influence of the cosolvent on the solvation sphere of the reactants.

Synthesis of Normuramic Acid Carba Analog and Its Glycopeptide Derivative Resistant to β-Elimination Splitting of the Side Chain

2000 ◽  
Vol 65 (11) ◽  
pp. 1726-1736 ◽  
Author(s):  
Miroslav Ledvina ◽  
Radka Pavelová ◽  
Anna Rohlenová ◽  
Jan Ježek ◽  
David Šaman
Keyword(s):  
Ethyl Ester ◽  
Alkaline Hydrolysis ◽  
Benzyl Ester ◽  
Side Chain ◽  
Propanoic Acid ◽  
Hydrolysis Of

Carba analogs of normuramic acid, i.e., 3-(benzyl 2-acetamido-2,3-dideoxy-4,6-O-isopropylidene-α-D-glucopyranosid-3-yl)propanoic acid derivatives (nitrile or esters) 3a-3c were prepared by addition of radicals generated from benzyl 2-acetamido-2-deoxy-4,6-O-isopropylidene-3-O-[(methylsulfanyl)thiocarbonyl]- (2a) or -3-O-(phenoxythiocarbonyl)-α-D-glucopyranoside (2b) with Bu3SnH to acrylonitrile or acryl esters. Alkaline hydrolysis of ethyl ester 3c afforded 3-(benzyl 2-acetamido-2,3-dideoxy-4,6-O-isopropylidene-α-D-glucopyranosid-3-yl)propanoic acid (5). Coupling of acid 5 with L-2-aminobutanoyl-D-isoglutamine benzyl ester trifluoroacetate and subsequent deprotection of the intermediate 6 furnished N-[3-(2-acetamido-2,3-dideoxy-α-D-glucopyranosid-3-yl)propanoyl]-L-2-aminobutanoyl-D-isoglutamine (7).

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