N.epsilon.-[[2-(Trimethylsilyl)ethoxy]carbonyl] derivatives of tri-L-lysine and tetra-L-lysine as potential intermediates in the block polymer synthesis of macromolecular drug conjugates

1989 ◽  
Vol 54 (23) ◽  
pp. 5551-5558 ◽  
Author(s):  
Andre Rosowsky ◽  
Joel E. Wright
Keyword(s):  
Polymer Synthesis ◽  
Block Polymer ◽  
Carbonyl Derivatives ◽  
Drug Conjugates ◽  
Derivatives Of ◽  
Macromolecular Drug

ChemInform Abstract: SYNTHESIS AND MOESSBAUER SPECTROSCOPIC STUDIES OF CARBONYL DERIVATIVES OF (PHTHALOCYANINATO)IRON(II)

1982 ◽  
Vol 13 (36) ◽  
Author(s):  
F. CALDERAZZO ◽  
S. FREDIANI ◽  
B. R. JAMES ◽  
G. PAMPALONI ◽  
K. J. REIMER ◽  
...  
Keyword(s):  
Spectroscopic Studies ◽  
Carbonyl Derivatives ◽  
Derivatives Of

Diazonium and Carbonyl Derivatives of Polyhedral Boranes

1964 ◽  
Vol 86 (1) ◽  
pp. 115-116 ◽  
Author(s):  
W. H. Knoth ◽  
J. C. Sauer ◽  
H. C. Miller ◽  
E. L. Muetterties
Keyword(s):  
Carbonyl Derivatives ◽  
Derivatives Of

ChemInform Abstract: Carbonyl Derivatives of Gold and Related Organometallics

ChemInform ◽  
2010 ◽  
Vol 28 (40) ◽  
pp. no-no
Author(s):  
D. B. DELL'AMICO ◽  
F. CALDERAZZO
Keyword(s):  
Carbonyl Derivatives ◽  
Derivatives Of

STUDY OF THE BIOLOGICAL PROPERTIES OF SEMI- AND THIOSEMICARBAZONES OF CARBONYL DERIVATIVES OF 4-BUTANOLIDES

2021 ◽  
Vol 55 (2 (255)) ◽  
pp. 103-111
Author(s):  
Tariel V. Ghochikyan ◽  
Armen S. Galstyan ◽  
Hrachik M. Stepanyan ◽  
Irina G. Korpakova ◽  
Alexander S. Kinzirsky
Keyword(s):  
Antitumor Activity ◽  
Green Alga ◽  
Biological Properties ◽  
Lymphocytic Leukemia ◽  
Thiazole Ring ◽  
Lewis Lung ◽  
Ehrlich's Ascites Tumor ◽  
Carbonyl Derivatives ◽  
Derivatives Of ◽  
Test Objects

Based on carbonyl derivatives of 4-substituted-4-butanolides, the appropriate semi- and thiosemicarbazones have been synthesized. It has been found that some representatives of thiosemicarbazones have pronounced algicidal activity against filamentous green alga Cladophora and blue-green alga (cyanobacterium) Synechocystis and some of the semi- and thiosemicarbazones exhibit moderate antitumor activity. The assessment of the antitumor activity of the compounds was carried out using strains of syngeneic and allogeneic tumor systems as test-objects: lymphocytic leukemia P-388, Lewis lung carcinoma, B16 melanoma and Ehrlich’s ascites tumor. It has also been established that some representatives of thiosemi­carbazones exhibit antimutagenic properties. It has been reliably proven that with the formation of a thiazole ring, all properties disappear and a new property in the series of thiazololactones is revealed – antibacterial․

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