Electrophilic olefin heterocyclization in organic synthesis. Stereoselective synthesis of 4,5-disubstituted .gamma.-lactams by iodine-induced lactam formation of .gamma.,.delta.-unsaturated thioimidates

1989 ◽  
Vol 54 (20) ◽  
pp. 4812-4822 ◽  
Author(s):  
Hiroki Takahata ◽  
Tamotsu Takamatsu ◽  
Takao Yamazaki
Keyword(s):  
Organic Synthesis ◽  
Stereoselective Synthesis ◽  
Gamma Delta

Synergistic Catalysis for Stereodivergent Synthesis of trans- and cis-Skipped Dienes

Synlett ◽  
2020 ◽  
Vol 31 (18) ◽  
pp. 1741-1746
Author(s):  
Shenqqing Zhu ◽  
Lingling Chu ◽  
Fang Wang
Keyword(s):  
Transition Metal ◽  
Organic Synthesis ◽  
Stereoselective Synthesis ◽  
Triplet Energy ◽  
Synergistic Catalysis ◽  
The Cross ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed ◽  
Vinyl Triflates

Catalytic, stereoselective synthesis of skipped dienes is an important topic in organic synthesis. Summarized here are the transition-metal-catalyzed stereoselective approaches and a new, photoinduced stereodivergent strategy reported by our group recently. Our strategy utilizes a synergistic photoredox/nickel protocol to enable the cross-electrophile coupling of allylic carbonates and vinyl triflates to construct 1,4-dienes, the stereoselectivity of which was tuned by the triplet energy (E T) photocatalysts employed, offering a convenient and stereodivergent solution to (E)- and (Z)-1,4-dienes from one set of substrates.

scholarly journals In-flow enantioselective homogeneous organic synthesis

2021 ◽  
Vol 10 (1) ◽  
pp. 768-778
Author(s):  
Alessandra Puglisi ◽  
Sergio Rossi ◽  
Fabian Herbrik ◽  
Fabrizio Medici ◽  
Maurizio Benaglia
Keyword(s):  
Organic Synthesis ◽  
Stereoselective Synthesis ◽  
Three Dimensional ◽  
Special Focus ◽  
Flow Reactors ◽  
Enabling Technologies

Abstract The use of enabling technologies, such as flow reactors, three-dimensional-printed devices, and electrochemistry, in the stereoselective synthesis of enantioenriched compounds is presented, with a special focus on the most significant contributions to the field reported in the last few years.

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