Improved Synthesis of RG-14893, a High-Affinity Leukotriene B4 Receptor Antagonist, via a Photochemical Wolff Rearrangement

1995 ◽  
Vol 60 (10) ◽  
pp. 3249-3251 ◽  
Author(s):  
Israil Pendrak ◽  
Pamela A. Chambers
Keyword(s):  
Receptor Antagonist ◽  
Leukotriene B4 ◽  
Wolff Rearrangement ◽  
High Affinity ◽  
Leukotriene B4 Receptor

(E)-3-[[[[6-(2-Carboxyethenyl)-5-[[8-(4-methoxyphenyl)octyl]oxy]-2-pyridinyl]methyl]thio]methyl]benzoic acid: a novel high-affinity leukotriene B4 receptor antagonist

1993 ◽  
Vol 36 (18) ◽  
pp. 2703-2705 ◽  
Author(s):  
Robert A. Daines ◽  
Pamela A. Chambers ◽  
Israil Pendrak ◽  
Dalia R. Jakas ◽  
Henry M. Sarau ◽  
...  
Keyword(s):  
Benzoic Acid ◽  
Receptor Antagonist ◽  
Leukotriene B4 ◽  
High Affinity ◽  
Leukotriene B4 Receptor

4-[2-[Methyl(2-phenethyl)amino]-2-oxoethyl]-8-(phenylmethoxy)-2-naphthalenecarboxylic acid: a high affinity, competitive, orally active leukotriene B4 receptor antagonist

1992 ◽  
Vol 35 (22) ◽  
pp. 4253-4255 ◽  
Author(s):  
Fu Chih Huang ◽  
Wan Kit Chan ◽  
James D. Warus ◽  
Mathew M. Morrissette ◽  
Kevin J. Moriarty ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Leukotriene B4 ◽  
High Affinity ◽  
Leukotriene B4 Receptor ◽  
Orally Active

ChemInform Abstract: The Synthesis of an Aminohexyl-Containing Analogue of the Chromanol Leukotriene B4 Receptor Antagonist CP-195543: A Scaffold for the Preparation of Derivatized Analogues.

ChemInform ◽  
2000 ◽  
Vol 31 (47) ◽  
pp. no-no
Author(s):  
Brian P. Jones ◽  
Klaas Schildknegt ◽  
Kathyrn F. Wright ◽  
Henry J. Showell ◽  
James P. Dittami ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Leukotriene B4 ◽  
Leukotriene B4 Receptor

Effect of leukotriene B4 receptor antagonist (ONO4057) on hepatic allografting in rats

2000 ◽  
Vol 32 (7) ◽  
pp. 2340 ◽  
Author(s):  
M Tanaka ◽  
T Tamaki ◽  
Y Konoeda ◽  
Y Uchida ◽  
T Kaizu ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Leukotriene B4 ◽  
Leukotriene B4 Receptor

Antiinflammatory effects of second-generation leukotriene B4 receptor antagonist, SC-53228: Impact upon Leukotriene B4- and 12(R)-HETE- mediated events

Inflammation ◽  
1995 ◽  
Vol 19 (2) ◽  
pp. 193-205 ◽  
Author(s):  
D. J. Fretland ◽  
C. P. Anglin ◽  
M. Bremer ◽  
P. Isakson ◽  
D. L. Widomski ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Second Generation ◽  
Leukotriene B4 ◽  
Antiinflammatory Effects ◽  
Leukotriene B4 Receptor
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