An enantioselective synthesis of the topically-active carbonic anhydrase inhibitor MK-0507: 5,6-dihydro-(S)-4-(ethylamino)-(S)-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide hydrochloride

1993 ◽  
Vol 58 (7) ◽  
pp. 1672-1679 ◽  
Author(s):  
Thomas J. Blacklock ◽  
Paul Sohar ◽  
John W. Butcher ◽  
T. Lamanec ◽  
E. J. J. Grabowski
Keyword(s):  
Carbonic Anhydrase ◽  
Carbonic Anhydrase Inhibitor ◽  
Enantioselective Synthesis ◽  
Active Carbonic Anhydrase

ChemInform Abstract: Enantioselective Synthesis of AL-4414A, a Topically Active Carbonic Anhydrase Inhibitor.

ChemInform ◽  
2010 ◽  
Vol 29 (20) ◽  
pp. no-no
Author(s):  
M. T. DUPRIEST ◽  
P. W. ZINKE ◽  
R. E. CONROW ◽  
D. KUZMICH ◽  
A. P. DANTANARAYANA ◽  
...  
Keyword(s):  
Carbonic Anhydrase ◽  
Carbonic Anhydrase Inhibitor ◽  
Enantioselective Synthesis ◽  
Active Carbonic Anhydrase

Enantioselective Synthesis of AL-4414A, a Topically Active Carbonic Anhydrase Inhibitor

1997 ◽  
Vol 62 (26) ◽  
pp. 9372-9375 ◽  
Author(s):  
Mark T. DuPriest ◽  
Paul W. Zinke ◽  
Raymond E. Conrow ◽  
Daniel Kuzmich ◽  
Anura P. Dantanarayana ◽  
...  
Keyword(s):  
Carbonic Anhydrase ◽  
Carbonic Anhydrase Inhibitor ◽  
Enantioselective Synthesis ◽  
Active Carbonic Anhydrase

Structure of 6-aminobenzofuran-2-sulfonamide: A tropically active carbonic anhydrase inhibitor

1993 ◽  
Vol 23 (6) ◽  
pp. 519-522
Author(s):  
M. Datta ◽  
A. K. Das ◽  
S. K. Mazumdar ◽  
B. Mazumdar ◽  
S. K. Talapatra ◽  
...  
Keyword(s):  
Carbonic Anhydrase ◽  
Carbonic Anhydrase Inhibitor ◽  
Active Carbonic Anhydrase

ChemInform Abstract: Enantioselective Synthesis of Brinzolamide (AL-4862), a New Topical Carbonic Anhydrase Inhibitor. The “DCAT Route” to Thiophenesulfonamides.

ChemInform ◽  
2010 ◽  
Vol 30 (29) ◽  
pp. no-no
Author(s):  
Raymond E. Conrow ◽  
W. Dennis Dean ◽  
Paul W. Zinke ◽  
Michael E. Deason ◽  
Steven J. Sproull ◽  
...  
Keyword(s):  
Carbonic Anhydrase ◽  
Carbonic Anhydrase Inhibitor ◽  
Enantioselective Synthesis

Enantioselective Synthesis of Brinzolamide (AL-4862), a New Topical Carbonic Anhydrase Inhibitor. The “DCAT Route” to Thiophenesulfonamides

1999 ◽  
Vol 3 (2) ◽  
pp. 114-120 ◽  
Author(s):  
Raymond E. Conrow ◽  
W. Dennis Dean ◽  
Paul W. Zinke ◽  
Michael E. Deason ◽  
Steven J. Sproull ◽  
...  
Keyword(s):  
Carbonic Anhydrase ◽  
Carbonic Anhydrase Inhibitor ◽  
Enantioselective Synthesis
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