Design of a Gag Pentapeptide Analogue that Binds Human Cyclophilin A More Efficiently than the Entire Capsid Protein:  New Insights for the Development of Novel Anti-HIV-1 Drugs†

2000 ◽  
Vol 43 (9) ◽  
pp. 1770-1779 ◽  
Author(s):  
Quan Li ◽  
Mireille Moutiez ◽  
Jean-Baptiste Charbonnier ◽  
Karine Vaudry ◽  
André Ménez ◽  
...  
Keyword(s):  
Capsid Protein ◽  
Cyclophilin A ◽  
Anti Hiv ◽  
Hiv 1

scholarly journals Crystal structure of cyclophilin A complexed with a binding site peptide from the HIV-1 capsid protein

2008 ◽  
Vol 6 (11) ◽  
pp. 2297-2307 ◽  
Author(s):  
Felix F. Vajdos ◽  
Sanghee Yoo ◽  
Megan Houseweart ◽  
Wesley I. Sundquist ◽  
Christopher P. Hill
Keyword(s):  
Crystal Structure ◽  
Binding Site ◽  
Capsid Protein ◽  
Cyclophilin A ◽  
Hiv 1

Anti-HIV-1 Activity of pepRF1, a Proteolysis-Resistant CXCR4 Antagonist Derived from Dengue Virus Capsid Protein

2020 ◽  
Author(s):  
Iris Cadima-Couto ◽  
Alexandra Tauzin ◽  
João M. Freire ◽  
Tiago N. Figueira ◽  
Rúben D. M. Silva ◽  
...  
Keyword(s):  
Dengue Virus ◽  
Capsid Protein ◽  
Cxcr4 Antagonist ◽  
Virus Capsid ◽  
Anti Hiv ◽  
Virus Capsid Protein ◽  
Hiv 1

HIV-1 Capsid Protein and Cyclophilin A as New Targets for Anti-AIDS Therapeutic Agents

2007 ◽  
Vol 7 (3) ◽  
pp. 238-244 ◽  
Author(s):  
Jiebo Li ◽  
Shixing Tang ◽  
Indira Hewlett ◽  
Ming Yang
Keyword(s):  
Capsid Protein ◽  
Cyclophilin A ◽  
Therapeutic Agents ◽  
New Targets ◽  
Hiv 1

scholarly journals Structure-based identification of small molecule compounds targeting cell cyclophilin A with anti-HIV-1 activity

2007 ◽  
Vol 565 (1-3) ◽  
pp. 54-59 ◽  
Author(s):  
Shuai Chen ◽  
Xuemei Zhao ◽  
Jinzhi Tan ◽  
Hong Lu ◽  
Zhi Qi ◽  
...  
Keyword(s):  
Small Molecule ◽  
Cyclophilin A ◽  
Anti Hiv ◽  
Hiv 1

Latex bead immobilisation in PDMS matrix for the detection of p53 gene point mutation and anti-HIV-1 capsid protein antibodies

2004 ◽  
Vol 381 (5) ◽  
pp. 1019-1024 ◽  
Author(s):  
Christophe A. Marquette ◽  
Agn�s Degiuli ◽  
Emmanuelle Imbert-Laurenceau ◽  
Francois Mallet ◽  
Carole Chaix ◽  
...  
Keyword(s):  
Capsid Protein ◽  
Point Mutation ◽  
P53 Gene ◽  
Latex Bead ◽  
Anti Hiv ◽  
Hiv 1

scholarly journals Synthesis of HIV-1 capsid protein assembly inhibitor (CAP-1) and its analogues based on a biomass approach

2016 ◽  
Vol 14 (45) ◽  
pp. 10593-10598 ◽  
Author(s):  
Leonid V. Romashov ◽  
Valentine P. Ananikov
Keyword(s):  
Capsid Protein ◽  
Organic Synthesis ◽  
Low Cost ◽  
Protein Assembly ◽  
Pharmaceutical Substance ◽  
Platform Chemical ◽  
Anti Hiv ◽  
Hiv 1

The potential of a biomass-derived platform chemical is explored in the low cost sustainable organic synthesis of an anti-HIV pharmaceutical substance with flexible and variable units.

scholarly journals Mutation in the loop C-terminal to the cyclophilin A binding site of HIV-1 capsid protein disrupts proper virus assembly and infectivity

Retrovirology ◽  
2007 ◽  
Vol 4 (1) ◽  
pp. 19 ◽  
Author(s):  
Samir Abdurahman ◽  
Stefan Höglund ◽  
Anders Höglund ◽  
Anders Vahlne
Keyword(s):  
Binding Site ◽  
Capsid Protein ◽  
Virus Assembly ◽  
Cyclophilin A ◽  
Hiv 1

scholarly journals Discovery of novel 1,4-disubstituted 1,2,3-triazole phenylalanine derivatives as HIV-1 capsid inhibitors

RSC Advances ◽  
2019 ◽  
Vol 9 (50) ◽  
pp. 28961-28986 ◽  
Author(s):  
Xiangyi Jiang ◽  
Gaochan Wu ◽  
Waleed A. Zalloum ◽  
Megan E. Meuser ◽  
Alexej Dick ◽  
...  
Keyword(s):  
Capsid Protein ◽  
Click Reaction ◽  
Protein Inhibitors ◽  
Anti Hiv ◽  
Hiv 1

Novel phenylalanine derivatives were discovered as HIV-1 capsid protein inhibitors via “click reaction”. Most of them exhibited remarkable anti-HIV-1 activity.

Anti HIV-1 activity of a hydrophilic cyclosporin derivative with improved binding affinity to cyclophilin A

1996 ◽  
Vol 6 (1) ◽  
pp. 23-26 ◽  
Author(s):  
Christos Papageorgiou ◽  
Jean-Jacques Sanglier ◽  
René Traber
Keyword(s):  
Binding Affinity ◽  
Cyclophilin A ◽  
Anti Hiv ◽  
Hiv 1
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