Synthesis, Structure−Activity Relationships, and Characterization of Novel Nonsteroidal and Selective Androgen Receptor Modulators

2009 ◽  
Vol 52 (22) ◽  
pp. 7186-7191 ◽  
Author(s):  
Nathalie Schlienger ◽  
Birgitte W. Lund ◽  
Jan Pawlas ◽  
Fabrizio Badalassi ◽  
Fabio Bertozzi ◽  
...  
Keyword(s):  
Androgen Receptor ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Selective Androgen Receptor Modulators ◽  
Receptor Modulators

Characterization of equine urinary metabolites of selective androgen receptor modulators (SARMs) S1, S4 and S22 for doping control purposes

2015 ◽  
Vol 7 (8) ◽  
pp. 673-683 ◽  
Author(s):  
Annelie Hansson ◽  
Heather Knych ◽  
Scott Stanley ◽  
Mario Thevis ◽  
Ulf Bondesson ◽  
...  
Keyword(s):  
Androgen Receptor ◽  
Urinary Metabolites ◽  
Doping Control ◽  
Selective Androgen Receptor Modulators ◽  
Receptor Modulators

Development of an Analytical Methodology for the Qualitative and Quantitative Characterization of Capsules with Andarine, in Order to Use them to Investigate the Pharmacotoxicological Profile of the Substance

2019 ◽  
Vol 70 (8) ◽  
pp. 2759-2763
Author(s):  
Amalia Miklos ◽  
Amelia Tero Vescan ◽  
Lenard Farczadi ◽  
Silvia Imre ◽  
Camil Eugen Vari ◽  
...  
Keyword(s):  
Androgen Receptor ◽  
The Internet ◽  
Mass Content ◽  
European Pharmacopoeia ◽  
Quantitative Characterization ◽  
Analytical Methodology ◽  
Qualitative And Quantitative ◽  
Selective Androgen Receptor Modulators ◽  
Receptor Modulators

Andarine is one of the most commonly used doping substance between selective androgen receptor modulators (SARMs). The purpose of our study is to characterize qualitatively and quantitatively andarine capsules purchased legally via the Internet through a rapid and precise UHPLC method and the uniformity of mass, content and dissolution assays were determined following the methodology of the European Pharmacopoeia 8th Ed. Regarding the uniformity of mass, the capsules are within the permissible limits, but regarding the active substance content, an average of 4.99 mg of andarine/capsule was obtained (with an RSD of 5.41%) from the 25 mg/capsule declared by the manufacturer.

Characterization of In Vitro Synthesized Equine Metabolites of the Selective Androgen Receptor Modulators S24 and S4

2012 ◽  
Vol 32 (9) ◽  
pp. 562-568 ◽  
Author(s):  
Oliver Krug ◽  
Andreas Thomas ◽  
Simon Beuck ◽  
Ina Schenk ◽  
Marc Machnik ◽  
...  
Keyword(s):  
Androgen Receptor ◽  
Selective Androgen Receptor Modulators ◽  
Receptor Modulators

scholarly journals Design, Synthesis, and Biological Characterization of Metabolically Stable Selective Androgen Receptor Modulators

2004 ◽  
Vol 47 (4) ◽  
pp. 993-998 ◽  
Author(s):  
Craig A. Marhefka ◽  
Wenqing Gao ◽  
Kiwon Chung ◽  
Juhyun Kim ◽  
Yali He ◽  
...  
Keyword(s):  
Androgen Receptor ◽  
Biological Characterization ◽  
Design Synthesis ◽  
Selective Androgen Receptor Modulators ◽  
Receptor Modulators
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