The Design, Synthesis, and Antiviral Activity of Monofluoro and Difluoro Analogues of 4′-Azidocytidine against Hepatitis C Virus Replication: The Discovery of 4′-Azido-2′-deoxy-2′-fluorocytidine and 4′-Azido-2′-dideoxy-2′,2′-difluorocytidine

2009 ◽  
Vol 52 (9) ◽  
pp. 2971-2978 ◽  
Author(s):  
David B. Smith ◽  
Genadiy Kalayanov ◽  
Christian Sund ◽  
Anna Winqvist ◽  
Tatiana Maltseva ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Antiviral Activity ◽  
Virus Replication ◽  
Design Synthesis

The Design, Synthesis, and Antiviral Activity of 4′-Azidocytidine Analogues against Hepatitis C Virus Replication: The Discovery of 4′-Azidoarabinocytidine

2009 ◽  
Vol 52 (1) ◽  
pp. 219-223 ◽  
Author(s):  
David B. Smith ◽  
Genadiy Kalayanov ◽  
Christian Sund ◽  
Anna Winqvist ◽  
Pedro Pinho ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Antiviral Activity ◽  
Virus Replication ◽  
Design Synthesis

Design, Synthesis, and Antiviral Activity of 2‘-Deoxy-2‘-fluoro-2‘-C-methylcytidine, a Potent Inhibitor of Hepatitis C Virus Replication

2005 ◽  
Vol 48 (17) ◽  
pp. 5504-5508 ◽  
Author(s):  
Jeremy L. Clark ◽  
Laurent Hollecker ◽  
J. Christian Mason ◽  
Lieven J. Stuyver ◽  
Phillip M. Tharnish ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Antiviral Activity ◽  
Virus Replication ◽  
Potent Inhibitor ◽  
Design Synthesis

Ferrocene-based inhibitors of hepatitis C virus replication that target NS5A with low picomolar in vitro antiviral activity

2018 ◽  
Vol 28 (21) ◽  
pp. 3463-3471 ◽  
Author(s):  
Venkat R. Gadhachanda ◽  
Kyle J. Eastman ◽  
Qiuping Wang ◽  
Avinash S. Phadke ◽  
Dharaben Patel ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Antiviral Activity ◽  
Virus Replication

Expressional screening of interferon-stimulated genes for antiviral activity against hepatitis C virus replication

2006 ◽  
Vol 13 (10) ◽  
pp. 690-700 ◽  
Author(s):  
Y. Itsui ◽  
N. Sakamoto ◽  
M. Kurosaki ◽  
N. Kanazawa ◽  
Y. Tanabe ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Antiviral Activity ◽  
Virus Replication ◽  
Interferon Stimulated Genes

scholarly journals Design, Synthesis, and Antiviral Activity of Adenosine 5‘-Phosphonate Analogues as Chain Terminators against Hepatitis C Virus

2005 ◽  
Vol 48 (8) ◽  
pp. 2867-2875 ◽  
Author(s):  
Yung-hyo Koh ◽  
Jae Hoon Shim ◽  
Jim Zhen Wu ◽  
Weidong Zhong ◽  
Zhi Hong ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Antiviral Activity ◽  
Design Synthesis ◽  
Chain Terminators

Design, synthesis, and antiviral properties of 4′-substituted ribonucleosides as inhibitors of hepatitis C virus replication: The discovery of R1479

2007 ◽  
Vol 17 (9) ◽  
pp. 2570-2576 ◽  
Author(s):  
David B. Smith ◽  
Joseph A. Martin ◽  
Klaus Klumpp ◽  
Stewart J. Baker ◽  
Peter A. Blomgren ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Replication ◽  
Design Synthesis

Mechanistic dynamics of Hepatitis C virus replication in single liver cells

2013 ◽  
Vol 51 (01) ◽  
Author(s):  
MM Knodel ◽  
P Targett-Adams ◽  
A Grillo ◽  
S Reiter ◽  
E Herrmann ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Replication ◽  
Liver Cells

Role of autophagy in hepatitis C virus replication

2019 ◽  
Author(s):  
WI Twu ◽  
K Tabata ◽  
D Paul ◽  
R Bartenschlager
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Replication
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