scholarly journals Inhibition of Cancer-Associated Mutant Isocitrate Dehydrogenases: Synthesis, Structure–Activity Relationship, and Selective Antitumor Activity

2014 ◽  
Vol 57 (20) ◽  
pp. 8307-8318 ◽  
Author(s):  
Zhen Liu ◽  
Yuan Yao ◽  
Mari Kogiso ◽  
Baisong Zheng ◽  
Lisheng Deng ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity

New anthrahydrazone derivatives and their cisplatin-like complexes: synthesis, antitumor activity and structure–activity relationship

2019 ◽  
Vol 43 (47) ◽  
pp. 18685-18694 ◽  
Author(s):  
Rui-Xue Liu ◽  
Ying-Shu Wu ◽  
Yan-Cheng Liu ◽  
Ru-Yi Luo ◽  
Li-Dong Yang ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity

Two new cisplatin-like platinum(ii) complexes of new anthrahydrazones showed significant in vitro antitumor efficacies, which were totally different from that of cisplatin.

Synthesis and In Vitro Antitumor Activity of Novel Ring D Analogues of the Marine Pyridoacridine Ascididemin: Structure−Activity Relationship

2002 ◽  
Vol 45 (17) ◽  
pp. 3765-3771 ◽  
Author(s):  
Evelyne Delfourne ◽  
Francis Darro ◽  
Philippe Portefaix ◽  
Chantal Galaup ◽  
Sylvie Bayssade ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity

Synthesis and antitumor activity of novel N-substituted tetrahydro-β-carboline–imidazolium salt derivatives

2016 ◽  
Vol 14 (39) ◽  
pp. 9423-9430 ◽  
Author(s):  
Bei Zhou ◽  
Zheng-Fen Liu ◽  
Guo-Gang Deng ◽  
Wen Chen ◽  
Min-Yan Li ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Imidazolium Salt ◽  
Structure Activity

A series of novel N-substituted tetrahydro-β-carboline imidazolium salt derivatives were synthesized and their antitumor structure–activity relationship studies were reported.

Structure–activity relationship in the antitumor activity of 6-, 8- or 6,8-substituted 3-benzylamino-β-carboline derivatives

2012 ◽  
Vol 22 (10) ◽  
pp. 3506-3515 ◽  
Author(s):  
Reiko Ikeda ◽  
Takanori Kimura ◽  
Tatsuya Tsutsumi ◽  
Syunsuke Tamura ◽  
Norio Sakai ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity

Synthesis and antitumor activity of novel 2-substituted indoline imidazolium salt derivatives

2015 ◽  
Vol 13 (5) ◽  
pp. 1550-1557 ◽  
Author(s):  
Xiao-Liang Xu ◽  
Chun-Lei Yu ◽  
Wen Chen ◽  
Ying-Chao Li ◽  
Li-Juan Yang ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Imidazolium Salt ◽  
Structure Activity

A series of novel 2-substituted indoline imidazolium salt derivatives were synthesized and their antitumor structure–activity relationship studies were reported.

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