Potent, Orally Active Heterocycle-Based Combretastatin A-4 Analogues:  Synthesis, Structure−Activity Relationship, Pharmacokinetics, and In Vivo Antitumor Activity Evaluation

2002 ◽  
Vol 45 (8) ◽  
pp. 1697-1711 ◽  
Author(s):  
Le Wang ◽  
Keith W. Woods ◽  
Qun Li ◽  
Kenneth J. Barr ◽  
Richard W. McCroskey ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Activity Evaluation ◽  
Structure Activity ◽  
In Vivo Antitumor Activity ◽  
Orally Active

New anthrahydrazone derivatives and their cisplatin-like complexes: synthesis, antitumor activity and structure–activity relationship

2019 ◽  
Vol 43 (47) ◽  
pp. 18685-18694 ◽  
Author(s):  
Rui-Xue Liu ◽  
Ying-Shu Wu ◽  
Yan-Cheng Liu ◽  
Ru-Yi Luo ◽  
Li-Dong Yang ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity

Two new cisplatin-like platinum(ii) complexes of new anthrahydrazones showed significant in vitro antitumor efficacies, which were totally different from that of cisplatin.

Synthesis and In Vitro Antitumor Activity of Novel Ring D Analogues of the Marine Pyridoacridine Ascididemin: Structure−Activity Relationship

2002 ◽  
Vol 45 (17) ◽  
pp. 3765-3771 ◽  
Author(s):  
Evelyne Delfourne ◽  
Francis Darro ◽  
Philippe Portefaix ◽  
Chantal Galaup ◽  
Sylvie Bayssade ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity
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