scholarly journals Effects of Amino Acids on Melanoma Targeting and Clearance Properties of Tc-99m-Labeled Arg-X-Asp-Conjugated α-Melanocyte Stimulating Hormone Peptides

2013 ◽  
Vol 56 (21) ◽  
pp. 8793-8802 ◽  
Author(s):  
Adam M. Flook ◽  
Jianquan Yang ◽  
Yubin Miao
Keyword(s):  
Amino Acids ◽  
Melanocyte Stimulating Hormone ◽  
Stimulating Hormone

scholarly journals Contribution of the Conserved Amino Acids of the Melanocortin-4 Receptor in d-[Nle4,Phe7]-α-Melanocyte-stimulating Hormone Binding and Signaling

2007 ◽  
Vol 282 (30) ◽  
pp. 21712-21719 ◽  
Author(s):  
Min Chen ◽  
Minying Cai ◽  
Charles J. Aprahamian ◽  
Keith E. Georgeson ◽  
Victor Hruby ◽  
...  
Keyword(s):  
Amino Acids ◽  
Hormone Binding ◽  
Melanocyte Stimulating Hormone ◽  
Melanocortin 4 Receptor ◽  
Conserved Amino Acids ◽  
Stimulating Hormone

INCORPORATION OF 14C-LABELLED AMINO ACIDS INTO CORTICOTROPHIN-LIKE INTERMEDIATE LOBE PEPTIDE AND α-MELANOCYTE-STIMULATING HORMONE BY THE RAT PITUITARY NEUROINTERMEDIATE LOBE IN VITRO, AND THE IDENTIFICATION OF FOUR NEW PARS INTERMEDIA PEPTIDES

1976 ◽  
Vol 70 (2) ◽  
pp. 197-205 ◽  
Author(s):  
A. P. SCOTT ◽  
P. J. LOWRY ◽  
TJ. B. VAN WIMERSMA GREIDANUS
Keyword(s):  
Amino Acids ◽  
The Other ◽  
Pars Intermedia ◽  
Intermediate Lobe ◽  
Melanocyte Stimulating Hormone ◽  
Neurointermediate Lobe ◽  
Rat Pituitary ◽  
Stimulating Hormone

SUMMARY At least seven radioactive peptides, which fractionated on Biogel P6, were found in rat neurointermediate lobes after incubation for 6 h with [14C]proline. Only three of these could be tentatively identified; one as α-melanocyte-stimulating hormone (α-MSH) and two as forms of corticotrophin-like intermediate lobe peptide (CLIP). One other crossreacted partially with a β-melanocyte-stimulating hormone (β-MSH) antiserum, was acidically charged and eluted on Biogel P6 in roughly the same position as ACTH. The other three peptides showed no resemblance to α-MSH, CLIP, β-MSH or ACTH.

QUANTITATIVE RELATIONS IN THE AQUEOUS FLARE RESPONSE INDUCED BY α-MELANOCYTE STIMULATING HORMONE IN THE RABBIT EYES

1965 ◽  
Vol 49 (1) ◽  
pp. 166-176 ◽  
Author(s):  
K. Dyster-Aas ◽  
C. E. T. Krakau
Keyword(s):  
Subcutaneous Injection ◽  
Great Variability ◽  
Local Administration ◽  
Aqueous Flare ◽  
Melanocyte Stimulating Hormone ◽  
Flare Response ◽  
Stimulating Hormone

ABSTRACT The aqueous flare response (AFR) to MSH is induced in an increasing percentage of animals with increasing age. The great variability of the responses and the fact that local administration of MSH is not more efficient with lower doses than by subcutaneous injection indicate that the AFR is a complex result in which general factors play a part. The analysis of the variation of the responses has led to a procedure for testing the effect of different preparations.

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