scholarly journals Hit Identification and Optimization in Virtual Screening: Practical Recommendations Based on a Critical Literature Analysis

2013 ◽  
Vol 56 (17) ◽  
pp. 6560-6572 ◽  
Author(s):  
Tian Zhu ◽  
Shuyi Cao ◽  
Pin-Chih Su ◽  
Ram Patel ◽  
Darshan Shah ◽  
...  
Keyword(s):  
Virtual Screening ◽  
Literature Analysis ◽  
Hit Identification ◽  
Practical Recommendations ◽  
Critical Literature

scholarly journals Podlaskie Voivodeship as an Opportunity for the Development of the BRI in Europe

2021 ◽  
Vol 18 ◽  
pp. 338-344
Author(s):  
Joanna Gniedziejko ◽  
Łukasz Rybiński
Keyword(s):  
Swot Analysis ◽  
External Environment ◽  
Literature Analysis ◽  
Belt And Road Initiative ◽  
Internal Environment ◽  
Logical Construction ◽  
Course Of Action ◽  
Belt And Road ◽  
The Belt And Road ◽  
Critical Literature

This study aims to evaluate Podlaskie Voivodeship as an important element for the development of the Belt and Road Initiative, by identifying both the internal environment (in terms of strengths and weaknesses) as well as the external environment (in the context of opportunities and threats) of Podlaskie Voivodeship. The study was conducted using critical literature analysis, logical construction method, and SWOT analysis. The authors of the study identified and assessed the strengths and weaknesses of Podlaskie Voivodeship related to the development of the logistics infrastructure of the voivodeship in the light of the Belt and Road Initiative and the opportunities and threats associated with it. Factors of Podlaskie Voivodeship indicated in the article can influence the course of action to increase the competitive advantage of Podlaskie Voivodeship regarding the development of the Belt and Road Initiative in Europe. The study includes a comprehensive SWOT analysis of the Podlaskie Voivodeship in the context of the Belt and Road Initiative. Elements analyzed by the authors may have a significant impact on the development of the voivodeship's infrastructure network regarding the expansion of the BRI

Literature analysis of humor therapy research

2009 ◽  
Vol 8 (4) ◽  
pp. 35-47
Author(s):  
Laura E. Harkins
Keyword(s):  
Alternative Therapies ◽  
Limiting Factors ◽  
Future Research ◽  
Recreational Therapy ◽  
Literature Analysis ◽  
Psychological Benefits ◽  
Specific Analysis ◽  
The Status ◽  
Practical Recommendations ◽  
Facilitation Techniques

Alternative therapies and creative facilitation techniques assist professionals in overcoming common client barriers such as boredom, passivity, and indifference or unresponsiveness to treatments. Humor therapy or therapeutic humor is one such facilitation technique that is no laughing matter, as research indicates its effectiveness extends much further than fun and smiles. Humor therapy is creating a humorous environment implemented through active and/or passive means to treat participants’ symptoms by eliciting laughter and joy. Little exists, however, that summarizes the status of data-based research on this topic. Therefore, the purpose of this article is to provide a literature analysis comprising the physiological and psychological benefits of humor therapy utilizing research published within the last 10 years. In addition, specific analysis of methodology, identification of limiting factors, exploration of future research implications, and practical recommendations for recreational therapy professionals are addressed.

Virtual screening: a real screening complement to high-throughput screening

2002 ◽  
Vol 30 (4) ◽  
pp. 797-799 ◽  
Author(s):  
J. Mestres
Keyword(s):  
Virtual Screening ◽  
High Throughput ◽  
High Throughput Screening ◽  
Oestrogen Receptor ◽  
Essential Elements ◽  
The Other ◽  
Receptor Subtype ◽  
Other Hand ◽  
Hit Identification

Virtual screening is being routinely used as an integral part of today's hit-identification strategies for, on one hand, prioritizing large corporate screening collections and, on the other hand, to extend the scope of screening to external databases. A brief description of the essential elements required for virtual screening and an application example to the identification of agonist hits for the oestrogen receptor subtype ERα are presented.

scholarly journals The Strategy of the Eurasian Economic Union Extra-Regional Integration

2021 ◽  
Vol 18 ◽  
pp. 67-77
Author(s):  
Agnieszka Konopelko ◽  
Katarzyna Czerewacz-Filipowicz
Keyword(s):  
Empirical Analysis ◽  
Regional Integration ◽  
Literature Analysis ◽  
Eurasian Economic Union ◽  
Comparative Advantages ◽  
Economic Union ◽  
The Impact ◽  
The Relationship ◽  
Theoretical Overview ◽  
Critical Literature

The main purpose of the research presented in the article is to answer the question of whether or notthe Eurasian Economic Union has strategic opportunities to initiate integration processes with third countriesand built comparative advantages. The authors identify the channels of its integration with third countries aswell as assess their effectiveness based on the relationship with Vietnam, Singapore, Iran and China. Thefollowing methods were used: a critical literature analysis, an empirical analysis of the official documents, alogical construct method, an analytical theoretical overview of the Eurasian Economic Union external strategy,as well as statistical methods. Subsequently, based on the results obtained, a SWOT (Strengths, Weaknesses,Opportunities, Threats) analysis was carried out. The work diagnoses the main vectors of the EurasianEconomic Union strategy, analyses its institutional extra-regional integration as well as defines the scope andmain channels of the influence of business and logistics on extra-regional integration. The main achievement ofthe research presented in the article is the diagnosis and assessment of the impact channels of EurasianEconomic Union extra-regional integration. The research points out that the organisation has an effective extraregional policy towards very different Eurasian countries and uses many channels of influence.

scholarly journals Analysis of the 5S method functioning in a production company

2020 ◽  
Vol 2020 (146) ◽  
pp. 523-531
Author(s):  
Radosław WOLNIAK ◽  
Keyword(s):  
Industrial Organization ◽  
Design Methodology ◽  
Industrial Enterprise ◽  
Literature Analysis ◽  
Study Analysis ◽  
Case Study Analysis ◽  
Enterprise Design ◽  
Production Company ◽  
Critical Literature

Purpose: The goal of the paper is to analyses process of implementation and effectiveness of 5S method in an industrial enterprise. Design/methodology/approach: Critical literature analysis, questionnaire analysis, case study analysis. Findings: On theexample of industrial organization that was in the presented paper an analysis of effectivenes of 5S implementation. On the basis of conducted analysis the main objectives of using 5S are: order in the workplace, maintenance of cleanliness and efficiency of machines and devices, shorter duration of activities. The main causes of problems with 5S implementation are connected with no time to do the work and lack of funds. The overall rating of efficiency of 5S method in analyzed enterprise is very good. Originality/value: Detailed analysis of main objectives of using 5S method and the main causes of problems with it in the industrial enterprise

scholarly journals Back Cover: Hit Identification of a Novel Dual Binder forh-telo/c-mycG-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement (ChemMedChem 16/2016)

ChemMedChem ◽  
2016 ◽  
Vol 11 (16) ◽  
pp. 1875-1875
Author(s):  
Roberta Rocca ◽  
Giosuè Costa ◽  
Anna Artese ◽  
Lucia Parrotta ◽  
Francesco Ortuso ◽  
...  
Keyword(s):  
Virtual Screening ◽  
Back Cover ◽  
Hit Identification

Modeling Choices for Virtual Screening Hit Identification

2011 ◽  
Vol 30 (9) ◽  
pp. 765-777 ◽  
Author(s):  
Charles Bergeron ◽  
Michael Krein ◽  
Gregory Moore ◽  
Curt M. Breneman ◽  
Kristin P. Bennett
Keyword(s):  
Virtual Screening ◽  
Hit Identification
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