Synthesis and Structure–Activity Relationship Studies of Novel Dual Inhibitors of Soluble Epoxide Hydrolase and 5-Lipoxygenase

2013 ◽  
Vol 56 (4) ◽  
pp. 1777-1781 ◽  
Author(s):  
Karin Meirer ◽  
Carmen B. Rödl ◽  
Joanna M. Wisniewska ◽  
Sven George ◽  
Ann-Kathrin Häfner ◽  
...  
Keyword(s):  
Epoxide Hydrolase ◽  
Soluble Epoxide Hydrolase ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Dual Inhibitors

scholarly journals Structure–Activity Relationship of Pyrrolyl Diketo Acid Derivatives as Dual Inhibitors of HIV-1 Integrase and Reverse Transcriptase Ribonuclease H Domain

2015 ◽  
Vol 58 (4) ◽  
pp. 1915-1928 ◽  
Author(s):  
Giuliana Cuzzucoli Crucitti ◽  
Mathieu Métifiot ◽  
Luca Pescatori ◽  
Antonella Messore ◽  
Valentina Noemi Madia ◽  
...  
Keyword(s):  
Reverse Transcriptase ◽  
Structure Activity Relationship ◽  
Ribonuclease H ◽  
Activity Relationship ◽  
Structure Activity ◽  
Dual Inhibitors ◽  
Relationship Of ◽  
Hiv 1

A structure-activity relationship study of flavonoids as dual inhibitors of LOX and COX

2013 ◽  
Vol 65 ◽  
pp. S47
Author(s):  
D. Ribeiro ◽  
M. Freitas ◽  
S.M. Tomé ◽  
A.M.S. Silva ◽  
G. Porto ◽  
...  
Keyword(s):  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Dual Inhibitors ◽  
Relationship Study

Comprehensive structure-activity relationship (SAR) investigation of C-aryl glycoside derivatives for the development of SGLT1/SGLT2 dual inhibitors

2021 ◽  
Author(s):  
Yunting Xin ◽  
Shuhao Zhou ◽  
Huibin Wang ◽  
Baichun Hu ◽  
Zhigang Zhang ◽  
...  
Keyword(s):  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Sodium Dependent ◽  
Dual Inhibitors ◽  
Aryl Glycoside

Human sodium dependent glucose co-transporters (SGLTs) are the attractive targets for diabetes, and the development of SGLT1/SGLT2 dual inhibitors has received substantial attention in recent years due to their better...

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