Targeting the Binding Function 3 (BF3) Site of the Androgen Receptor Through Virtual Screening. 2. Development of 2-((2-phenoxyethyl) thio)-1H-benzimidazole Derivatives

2013 ◽  
Vol 56 (3) ◽  
pp. 1136-1148 ◽  
Author(s):  
Ravi Shashi Nayana Munuganti ◽  
Eric Leblanc ◽  
Peter Axerio-Cilies ◽  
Christophe Labriere ◽  
Kate Frewin ◽  
...  
Keyword(s):  
Androgen Receptor ◽  
Virtual Screening ◽  
Benzimidazole Derivatives ◽  
Binding Function

Correction to Targeting the Binding Function 3 (BF3) Site of the Human Androgen Receptor through Virtual Screening

2011 ◽  
Vol 55 (1) ◽  
pp. 565-565 ◽  
Author(s):  
Nathan A. Lack ◽  
Peter Axerio-Cilies ◽  
Peyman Tavassoli ◽  
Frank Q. Han ◽  
Ka Hong Chan ◽  
...  
Keyword(s):  
Androgen Receptor ◽  
Virtual Screening ◽  
Binding Function ◽  
Human Androgen Receptor

scholarly journals Targeting the Binding Function 3 (BF3) Site of the Human Androgen Receptor through Virtual Screening.

2011 ◽  
Vol 54 (24) ◽  
pp. 8563-8573 ◽  
Author(s):  
Nathan A. Lack ◽  
Peter Axerio-Cilies ◽  
Peyman Tavassoli ◽  
Frank Q. Han ◽  
Ka Hong Chan ◽  
...  
Keyword(s):  
Androgen Receptor ◽  
Virtual Screening ◽  
Binding Function ◽  
Human Androgen Receptor

Participation of Critical Residues from the Extreme C-Terminal End of the Human Androgen Receptor in the Ligand Binding Function†

Biochemistry ◽  
2001 ◽  
Vol 40 (29) ◽  
pp. 8431-8437 ◽  
Author(s):  
Bouchra Tahiri ◽  
Gilles Auzou ◽  
Jean-Claude Nicolas ◽  
Charles Sultan ◽  
Brigitte Lupo
Keyword(s):  
Androgen Receptor ◽  
Ligand Binding ◽  
Binding Function ◽  
Critical Residues ◽  
Human Androgen Receptor

SEARCHING BY METOD OF NEURAL NETWORK MODELING OF CONDENSED BENZIMIDAZOLE DERIVATIVES WITH MULTI-TARGET RAGE-INHIBITORY ACTIVITY

2020 ◽  
pp. 248-249
Author(s):  
O. Zhukovskaya ◽  
A. Spasov ◽  
A. Morkovnik ◽  
A. Kochetkov
Keyword(s):  
Neural Network ◽  
Virtual Screening ◽  
Network Model ◽  
Neural Network Model ◽  
Inhibitory Activity ◽  
Network Modeling ◽  
Inhibitory Effect ◽  
Benzimidazole Derivatives ◽  
Neural Network Modeling

Using a multitarget neural network model of RAGE-inhibitory activity, a consensus virtual screening of a library of new condensed benzimidazole derivatives was performed. Compounds with a essential RAGE-inhibitory effect have been found.

Abstract 3654: Targeting binding function-3 site on the androgen receptor to treat Enzalutamide-resistant prostate cancer

2015 ◽  
Author(s):  
Ravi Shashi Nayana Munuganti ◽  
Mohamed DH Hassona ◽  
Eric Leblanc ◽  
Emma T. Guns ◽  
Paul S. Rennie ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Androgen Receptor ◽  
Binding Function

scholarly journals Discovery of Novel Androgen Receptor Ligands by Structure-based Virtual Screening and Bioassays

2018 ◽  
Vol 16 (6) ◽  
pp. 416-427 ◽  
Author(s):  
Wenfang Zhou ◽  
Mojie Duan ◽  
Weitao Fu ◽  
Jinping Pang ◽  
Qin Tang ◽  
...  
Keyword(s):  
Androgen Receptor ◽  
Virtual Screening ◽  
Receptor Ligands

Discovery of 1H-Indole-2-carboxamides as Novel Inhibitors of the Androgen Receptor Binding Function 3 (BF3)

2014 ◽  
Vol 57 (15) ◽  
pp. 6867-6872 ◽  
Author(s):  
Fuqiang Ban ◽  
Eric Leblanc ◽  
Huifang Li ◽  
Ravi S. N. Munuganti ◽  
Kate Frewin ◽  
...  
Keyword(s):  
Androgen Receptor ◽  
Receptor Binding ◽  
Binding Function

scholarly journals Targeting Binding Function-3 of the Androgen Receptor Blocks Its Co-Chaperone Interactions, Nuclear Translocation, and Activation

2016 ◽  
Vol 15 (12) ◽  
pp. 2936-2945 ◽  
Author(s):  
Nada Lallous ◽  
Eric Leblanc ◽  
Ravi S.N. Munuganti ◽  
Mohamed D.H. Hassona ◽  
Nader Al Nakouzi ◽  
...  
Keyword(s):  
Androgen Receptor ◽  
Nuclear Translocation ◽  
Binding Function ◽  
Chaperone Interactions
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