Synthesis and Biological Evaluation of Pyrimidine-Based Dual Inhibitors of Human Epidermal Growth Factor Receptor 1 (HER-1) and HER-2 Tyrosine Kinases

2012 ◽  
Vol 55 (6) ◽  
pp. 2846-2857 ◽  
Author(s):  
Mi Young Cha ◽  
Kwang-Ok Lee ◽  
Seok-Jong Kang ◽  
Young Hee Jung ◽  
Ji Yeon Song ◽  
...  
Keyword(s):  
Epidermal Growth Factor Receptor ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Tyrosine Kinases ◽  
Growth Factor Receptor ◽  
Biological Evaluation ◽  
Dual Inhibitors ◽  
Her 2 ◽  
Epidermal Growth ◽  
Synthesis And Biological Evaluation

scholarly journals Design, Synthesis, and Biological Evaluation of 4-aminoquinazoline Appended-Benzofuran Hybrids as Epidermal Growth Factor Receptor Inhibitors

Proceedings ◽  
2019 ◽  
Vol 22 (1) ◽  
pp. 22
Author(s):  
Marole Maria Maluleka ◽  
Malose Jack Mphahlele
Keyword(s):  
Epidermal Growth Factor Receptor ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Targeted Therapies ◽  
Growth Factor Receptor ◽  
Biological Evaluation ◽  
Antitumor Drugs ◽  
Design Synthesis ◽  
Epidermal Growth ◽  
Synthesis And Biological Evaluation

Nitrogen-containing heterocycles such as quinazolines and benzofurans have received a great amount of interest in targeted therapies as antitumor drugs [1]. [...]

scholarly journals Synthesis and biological evaluation of an epidermal growth factor receptor-targeted peptide-conjugated phthalocyanine-based photosensitiser

RSC Advances ◽  
2019 ◽  
Vol 9 (36) ◽  
pp. 20652-20662 ◽  
Author(s):  
Evelyn Y. Xue ◽  
Roy C. H. Wong ◽  
Clarence T. T. Wong ◽  
Wing-Ping Fong ◽  
Dennis K. P. Ng
Keyword(s):  
Epidermal Growth Factor Receptor ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Cancer Cells ◽  
Growth Factor Receptor ◽  
Biological Evaluation ◽  
Epidermal Growth ◽  
High Cytotoxicity ◽  
Synthesis And Biological Evaluation

A peptide-conjugated zinc(ii) phthalocyanine has been prepared which can selectively bind to the epidermal growth factor receptor of cancer cells and induce high cytotoxicity upon illumination.

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