Nicotinic Acetylcholine Receptor Efficacy and Pharmacological Properties of 3-(Substituted phenyl)-2β-substituted Tropanes

F. Ivy Carroll; Bruce E. Blough; S. Wayne Mascarella; Hernán A. Navarro; J. Brek Eaton; Ronald, J. Lukas; M. Imad Damaj

doi:10.1021/jm100994w

Nicotinic Acetylcholine Receptor Efficacy and Pharmacological Properties of 3-(Substituted phenyl)-2β-substituted Tropanes

Journal of Medicinal Chemistry ◽

10.1021/jm100994w ◽

2010 ◽

Vol 53 (23) ◽

pp. 8345-8353 ◽

Cited By ~ 4

Author(s):

F. Ivy Carroll ◽

Bruce E. Blough ◽

S. Wayne Mascarella ◽

Hernán A. Navarro ◽

J. Brek Eaton ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Pharmacological Properties ◽

Nicotinic Acetylcholine

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α7 and β2 Nicotinic Acetylcholine Receptor Subunits Form Heteromeric Receptor Complexes that Are Expressed in the Human Cortex and Display Distinct Pharmacological Properties

PLoS ONE ◽

10.1371/journal.pone.0130572 ◽

2015 ◽

Vol 10 (6) ◽

pp. e0130572 ◽

Cited By ~ 22

Author(s):

Morten Skøtt Thomsen ◽

Ruud Zwart ◽

Daniel Ursu ◽

Majbrit Myrup Jensen ◽

Lars Hageman Pinborg ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Pharmacological Properties ◽

Nicotinic Acetylcholine ◽

Human Cortex ◽

Receptor Complexes

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The α9 Nicotinic Acetylcholine Receptor Shares Pharmacological Properties with Type A γ-Aminobutyric Acid, Glycine, and Type 3 Serotonin Receptors

Molecular Pharmacology ◽

10.1124/mol.55.2.248 ◽

1999 ◽

Vol 55 (2) ◽

pp. 248-254 ◽

Cited By ~ 64

Author(s):

Carla V. Rothlin ◽

Eleonora Katz ◽

Miguel Verbitsky ◽

A. Belén Elgoyhen

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Serotonin Receptors ◽

Type A ◽

Aminobutyric Acid ◽

Pharmacological Properties ◽

Nicotinic Acetylcholine ◽

Type 3

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Epibatidine: Pharmacological Properties of a Novel Nicotinic Acetylcholine Receptor Agonist and Analgesic Agent

CNS Drug Reviews ◽

10.1111/j.1527-3458.1996.tb00288.x ◽

1996 ◽

Vol 2 (1) ◽

pp. 21-39 ◽

Cited By ~ 37

Author(s):

James P. Sullivan ◽

Anthony W. Bannon

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Receptor Agonist ◽

Pharmacological Properties ◽

Analgesic Agent ◽

Nicotinic Acetylcholine

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Synthesis and Nicotinic Acetylcholine Receptor in Vitro and in Vivo Pharmacological Properties of 2′-Fluoro-3′-(substituted phenyl)deschloroepibatidine Analogues of 2′-Fluoro-3′-(4-nitrophenyl)deschloroepibatidine

Journal of Medicinal Chemistry ◽

10.1021/jm300575y ◽

2012 ◽

Vol 55 (14) ◽

pp. 6512-6522 ◽

Cited By ~ 23

Author(s):

Pauline Ondachi ◽

Ana Castro ◽

Charles W. Luetje ◽

M. Imad Damaj ◽

S. Wayne Mascarella ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Pharmacological Properties ◽

Nicotinic Acetylcholine

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ABT-089: Pharmacological Properties of a Neuronal Nicotinic Acetylcholine Receptor Agonist for the Potential Treatment of Cognitive Disorders

CNS Drug Reviews ◽

10.1111/j.1527-3458.2004.tb00011.x ◽

2006 ◽

Vol 10 (2) ◽

pp. 167-182 ◽

Cited By ~ 48

Author(s):

Lynne E. Rueter ◽

David J. Anderson ◽

Clark A. Briggs ◽

Diana L. Donnelly-Roberts ◽

Gary A. Gintant ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Receptor Agonist ◽

Cognitive Disorders ◽

Neuronal Nicotinic Acetylcholine Receptor ◽

Pharmacological Properties ◽

Potential Treatment ◽

Nicotinic Acetylcholine

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A-85380 [3-(2(S)-azetidinylmethoxy) pyridine]: In Vitro pharmacological properties of a novel, high affinity α4β2 nicotinic acetylcholine receptor ligand

Neuropharmacology ◽

10.1016/0028-3908(96)84644-2 ◽

1996 ◽

Vol 35 (6) ◽

pp. 725-734 ◽

Cited By ~ 90

Author(s):

James P. Sullivan ◽

Diana Donnelly-Roberts ◽

Clark A. Briggs ◽

David J. Anderson ◽

Murali Gopalakrishnan ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Pharmacological Properties ◽

Receptor Ligand ◽

Nicotinic Acetylcholine ◽

High Affinity

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A Series of α7 Nicotinic Acetylcholine Receptor Allosteric Modulators with Close Chemical Similarity but Diverse Pharmacological Properties

Molecular Pharmacology ◽

10.1124/mol.111.076026 ◽

2012 ◽

Vol 81 (5) ◽

pp. 710-718 ◽

Cited By ~ 37

Author(s):

JasKiran K. Gill ◽

Persis Dhankher ◽

Tom D. Sheppard ◽

Emanuele Sher ◽

Neil S. Millar

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Pharmacological Properties ◽

Allosteric Modulators ◽

Chemical Similarity ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine

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Synthesis, nicotinic acetylcholine receptor binding, and pharmacological properties of 3′-(substituted phenyl)deschloroepibatidine analogs

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2007.10.027 ◽

2008 ◽

Vol 16 (2) ◽

pp. 746-754 ◽

Cited By ~ 13

Author(s):

F. Ivy Carroll ◽

Yasuno Yokota ◽

Wei Ma ◽

Jeffrey R. Lee ◽

Lawrence E. Brieaddy ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Receptor Binding ◽

Pharmacological Properties ◽

Nicotinic Acetylcholine

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Synthesis, Nicotinic Acetylcholine Receptor Binding, and in Vitro and in Vivo Pharmacological Properties of 2′-Fluoro-(substituted thiophenyl)deschloroepibatidine Analogues

ACS Chemical Neuroscience ◽

10.1021/acschemneuro.6b00252 ◽

2016 ◽

Vol 8 (1) ◽

pp. 115-127 ◽

Cited By ~ 1

Author(s):

Pauline W. Ondachi ◽

Ana H. Castro ◽

Benjamin Sherman ◽

Charles W. Luetje ◽

M. Imad Damaj ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Receptor Binding ◽

Pharmacological Properties ◽

Nicotinic Acetylcholine

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Stable expression and pharmacological properties of the human α7 nicotinic acetylcholine receptor

European Journal of Pharmacology Molecular Pharmacology ◽

10.1016/0922-4106(95)00083-6 ◽

1995 ◽

Vol 290 (3) ◽

pp. 237-246 ◽

Cited By ~ 125

Author(s):

Murali Gopalakrishnan ◽

Bruno Buisson ◽

Edward Touma ◽

Tony Giordano ◽

Jeff E. Campbell ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Stable Expression ◽

Pharmacological Properties ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine

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