scholarly journals Investigation of the Lactam Side Chain Length Necessary for Optimal Indenoisoquinoline Topoisomerase I Inhibition and Cytotoxicity in Human Cancer Cell Cultures

2007 ◽  
Vol 50 (9) ◽  
pp. 2040-2048 ◽  
Author(s):  
Andrew Morrell ◽  
Michael S. Placzek ◽  
Jamin D. Steffen ◽  
Smitha Antony ◽  
Keli Agama ◽  
...  
2004 ◽  
Vol 47 (21) ◽  
pp. 5126-5139 ◽  
Author(s):  
Allison B. Edsall ◽  
Arasambattu K. Mohanakrishnan ◽  
Donglai Yang ◽  
Philip E. Fanwick ◽  
Ernest Hamel ◽  
...  

Steroids ◽  
2011 ◽  
Vol 76 (13) ◽  
pp. 1491-1504 ◽  
Author(s):  
Ganapathy Panchapakesan ◽  
Vasudevan Dhayalan ◽  
Nachiappan Dhatchana Moorthy ◽  
Nidhyanandan Saranya ◽  
Arasambattu K. Mohanakrishnan

1991 ◽  
Vol 46 (7-8) ◽  
pp. 706-708 ◽  
Author(s):  
Christiane Tempête ◽  
Michel Devys ◽  
Michel Barbier

Abstract Cell growth inhibitions on human cancer cell cultures were determined for the indole sulphur-containing phytoalexins cyclobrassinin, brassilexin (previously isolated from vegetables of the Cruciferae family) and their synthetic analogues 5-methoxybrassilexin and homocyclobrassinin. The most biologically active of these products is brassilexin (LD50= 8 μg/ml).


1987 ◽  
Vol 11 (5) ◽  
pp. 373-378 ◽  
Author(s):  
A FIENNES ◽  
J WALTON ◽  
D WINTERBOURNE ◽  
D MCGLASHAN ◽  
J HERMONTAYLOR

1959 ◽  
Vol 102 (1) ◽  
pp. 63-67 ◽  
Author(s):  
C. M. Southam ◽  
M. Tai ◽  
E. L. Greene

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