Synthesis and Biological Evaluation ofN-Heterocyclic Indolyl Glyoxylamides as Orally Active Anticancer Agents

2003 ◽  
Vol 46 (9) ◽  
pp. 1706-1715 ◽  
Author(s):  
Wen-Tai Li ◽  
Der-Ren Hwang ◽  
Ching-Ping Chen ◽  
Chien-Wei Shen ◽  
Chen-Long Huang ◽  
...  
Keyword(s):  
Anticancer Agents ◽  
Biological Evaluation ◽  
Orally Active ◽  
Synthesis And Biological Evaluation

Synthesis and biological evaluation of 2-amino-1-thiazolyl imidazoles as orally active anticancer agents

2010 ◽  
Vol 30 (1) ◽  
pp. 164-175 ◽  
Author(s):  
Wen-Tai Li ◽  
Der-Ren Hwang ◽  
Jen-Shin Song ◽  
Ching-Ping Chen ◽  
Tung-Wei Chen ◽  
...  
Keyword(s):  
Anticancer Agents ◽  
Biological Evaluation ◽  
Orally Active ◽  
Synthesis And Biological Evaluation

Synthesis and Biological Evaluation of 1,3,4-Thiadiazole Linked Phthalimide Derivatives as Anticancer Agents

2017 ◽  
Vol 14 (10) ◽  
Author(s):  
Zahra Rezaei ◽  
Setareh Moghimi ◽  
Rezvan Javaheri ◽  
Mehdi Asadi ◽  
Mohammad Mahdavi ◽  
...  
Keyword(s):  
Anticancer Agents ◽  
Biological Evaluation ◽  
Synthesis And Biological Evaluation

Design, Synthesis and Biological Evaluation of Tetrahydrodibenzo[b,g][1,8]napthyridinones as Potential Anticancer Agents and Novel Aurora Kinases Inhibitors

2021 ◽  
Vol 6 (14) ◽  
pp. 3444-3452
Author(s):  
Asha V. Chate ◽  
Pramod A. Tagad ◽  
Giribala M. Bondle ◽  
Aniket P. Sarkate ◽  
Shailee V. Tiwari ◽  
...  
Keyword(s):  
Anticancer Agents ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Aurora Kinases ◽  
Synthesis And Biological Evaluation

scholarly journals Molecular modeling study, synthesis and biological evaluation of combretastatin A-4 analogues as anticancer agents and tubulin inhibitors

MedChemComm ◽  
2018 ◽  
Vol 9 (2) ◽  
pp. 316-327 ◽  
Author(s):  
Yang Ping Quan ◽  
Li Ping Cheng ◽  
Tian Chi Wang ◽  
Wan Pang ◽  
Fan Hong Wu ◽  
...  
Keyword(s):  
Molecular Modeling ◽  
Anticancer Agents ◽  
Hepg2 Cells ◽  
Binding Mode ◽  
Biological Evaluation ◽  
Tubulin Inhibitors ◽  
Molecular Modeling Study ◽  
Synthesis And Biological Evaluation ◽  
Modeling Study

Compound 13a, more effective than CA-4 against HepG2 cells and tubulin, and the proposed binding mode for 13a.

Synthesis and biological evaluation of novel withangulatin A derivatives as potential anticancer agents

2021 ◽  
Vol 108 ◽  
pp. 104690
Author(s):  
Wu-Xi Zhou ◽  
Chen Chen ◽  
Xiao-Qin Liu ◽  
Ying Li ◽  
Ling-Yi Kong ◽  
...  
Keyword(s):  
Anticancer Agents ◽  
Biological Evaluation ◽  
Synthesis And Biological Evaluation

scholarly journals Synthesis and biological evaluation of novel asymmetric naphthalene diimide derivatives as anticancer agents depending on ROS generation

MedChemComm ◽  
2018 ◽  
Vol 9 (8) ◽  
pp. 1377-1385 ◽  
Author(s):  
Xiaojuan Xu ◽  
Senzhen Wang ◽  
Yuan Chang ◽  
Chaochao Ge ◽  
Xinna Li ◽  
...  
Keyword(s):  
Anticancer Agents ◽  
Biological Evaluation ◽  
Hepatoma Cells ◽  
Ros Generation ◽  
Naphthalene Diimide ◽  
Induced Apoptosis ◽  
Synthesis And Biological Evaluation

Compound 3c induced apoptosis and autophagy and inhibited the migration of hepatoma cells depending on ROS generation.

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