Synthesis and in Vitro Evaluation of Quaternary Ammonium Derivatives of Chlorambucil and Melphalan, Anticancer Drugs Designed for the Chemotherapy of Chondrosarcoma

2002 ◽  
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Isabelle Giraud ◽  
Maryse Rapp ◽  
Jean-Claude Maurizis ◽  
Jean-Claude Madelmont
2006 ◽  
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Antoine Dorcier ◽  
Wee Han Ang ◽  
Sandra Bolaño ◽  
Luca Gonsalvi ◽  
Lucienne Juillerat-Jeannerat ◽  
...  

1991 ◽  
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Karen L. Meyer ◽  
Canino J. Marasco ◽  
Susan L. Morris-Natschke ◽  
Khalid S. Ishaq ◽  
Claude Piantadosi ◽  
...  

2007 ◽  
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Susanna M. Saario ◽  
Antti O. Kataja ◽  
Joel A. Castillo-Melendez ◽  
Tapio Nevalainen ◽  
...  

2006 ◽  
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Johnny Vercouillie ◽  
Sylvie Mavel ◽  
Laurent Galineau ◽  
Tiziana Ragusa ◽  
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2012 ◽  
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Nikolas Fokialakis ◽  
Xanthippi Alexi ◽  
Nektarios Aligiannis ◽  
Despina Siriani ◽  
Aggeliki K. Meligova ◽  
...  

2016 ◽  
Vol 107 (12) ◽  
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Ayako Aihara ◽  
Natsuki Abe ◽  
Koichiro Saruhashi ◽  
Tatsuro Kanaki ◽  
Taito Nishino

Author(s):  
Zahra Ould Kada ◽  
Tahar Benaissa ◽  
Nisserine Hamini-Kadar ◽  
Sofiane Daoudi

Starting from lauric acid two novel quaternary ammonium salts containing 1,3,4-Oxadiazoles nucleus derivative from N,N-Diethylaminoethyl Methacrylate (DEAEMA) and N,N-Dimethylaminoethyl Methacrylate (DMAEMA) was successfully synthesized and characterized by IR, 1H and 13C NMR, All the synthesized compounds were evaluated for their preliminary in vitro antifungal activity against three fungal strains such as Fusarium oxysporum, Fusarium commune and Fusarium rodelens. The synthesized compounds showed promising antifungal potential against the phytopathogenic test fungi.


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