Synthesis, Biological Evaluation, and Quantitative Structure−Activity Relationship Analysis of New Schiff Bases of Hydroxysemicarbazide as Potential Antitumor Agents†

Shijun Ren; Rubin Wang; Kenichi Komatsu; Patricia Bonaz-Krause; Yegor Zyrianov; Charles E. McKenna; Csaba Csipke; Zoltan A. Tokes; Eric J. Lien

doi:10.1021/jm010252q

Synthesis, Biological Evaluation, and Quantitative Structure−Activity Relationship Analysis of New Schiff Bases of Hydroxysemicarbazide as Potential Antitumor Agents†

Journal of Medicinal Chemistry ◽

10.1021/jm010252q ◽

2002 ◽

Vol 45 (2) ◽

pp. 410-419 ◽

Cited By ~ 185

Author(s):

Shijun Ren ◽

Rubin Wang ◽

Kenichi Komatsu ◽

Patricia Bonaz-Krause ◽

Yegor Zyrianov ◽

...

Keyword(s):

Schiff Bases ◽

Antitumor Agents ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Biological Evaluation ◽

Activity Relationship ◽

Quantitative Structure ◽

Relationship Analysis ◽

Structure Activity ◽

Potential Antitumor

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Design, synthesis, testing, and quantitative structure-activity relationship analysis of substituted salicylaldehyde Schiff bases of 1-amino-3-hydroxyguanidine tosylate as new antiviral agents against coronavirus

Journal of Medicinal Chemistry ◽

10.1021/jm00164a023 ◽

1990 ◽

Vol 33 (2) ◽

pp. 608-614 ◽

Cited By ~ 115

Author(s):

Pou Hsiung Wang ◽

James G. Keck ◽

Eric J. Lien ◽

Michael M. C. Lai

Keyword(s):

Schiff Bases ◽

Antiviral Agents ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Design Synthesis ◽

Relationship Analysis ◽

Structure Activity

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Synthesis, biological evaluation, and quantitative structure-activity relationship analysis of 2-hydroxy-1H-isoindolediones as new cytostatic agents

Journal of Medicinal Chemistry ◽

10.1021/jm00386a012 ◽

1987 ◽

Vol 30 (3) ◽

pp. 509-514 ◽

Cited By ~ 23

Author(s):

Carcy L. Chan ◽

Eric J. Lien ◽

Zoltan A. Tokes

Keyword(s):

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Biological Evaluation ◽

Activity Relationship ◽

Quantitative Structure ◽

Cytostatic Agents ◽

Relationship Analysis ◽

Structure Activity

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Synthesis, biological evaluation, and quantitative structure-activity relationship analysis of [.beta.-(aroylamino)ethyl]piperazines and -piperidines and [2-[(arylamino)carbonyl]ethyl]piperazines, -piperidines, -pyrazinopyridoindoles, and -pyrazinoisoquinolines. A new class of potent H1 antagonists

Journal of Medicinal Chemistry ◽

10.1021/jm00173a011 ◽

1990 ◽

Vol 33 (11) ◽

pp. 2970-2976 ◽

Cited By ~ 18

Author(s):

Mridula Saxena ◽

Shiv K. Agarwal ◽

G. K. Patnaik ◽

Anil K. Saxena

Keyword(s):

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Biological Evaluation ◽

Activity Relationship ◽

Quantitative Structure ◽

New Class ◽

Relationship Analysis ◽

Structure Activity ◽

H1 Antagonists

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Synthesis, Biological Evaluation and Quantitative Structure Activity Relationship Analysis of Nuclear-substituted Pargylines as Competitive Inhibitors of MAO-A and MAO-B

Journal of Pharmacy and Pharmacology ◽

10.1111/j.2042-7158.1991.tb03476.x ◽

1991 ◽

Vol 43 (11) ◽

pp. 750-757 ◽

Cited By ~ 8

Author(s):

ANMAR ALI ◽

J. B. ROBINSON

Keyword(s):

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Biological Evaluation ◽

Activity Relationship ◽

Quantitative Structure ◽

Mao B ◽

Relationship Analysis ◽

Structure Activity ◽

Competitive Inhibitors ◽

Mao A

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ChemInform Abstract: Synthesis, Biological Evaluation, and Quantitative Structure-Activity Relationship Analysis of 2-Hydroxy-1H-isoindolediones as New Cytostatic Agents.

ChemInform ◽

10.1002/chin.198731131 ◽

1987 ◽

Vol 18 (31) ◽

Author(s):

C. L. CHAN ◽

E. J. LIEN ◽

Z. A. TOKES

Keyword(s):

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Biological Evaluation ◽

Activity Relationship ◽

Quantitative Structure ◽

Cytostatic Agents ◽

Relationship Analysis ◽

Structure Activity

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Quantitative Structure-Activity Relationship Analysis of the Cation Permeability of the P2X2 Channel

Medicinal Chemistry ◽

10.2174/1573406053175210 ◽

2005 ◽

Vol 1 (2) ◽

pp. 109-115 ◽

Cited By ~ 3

Author(s):

Peter Mager ◽

Anje Weber ◽

Peter Illes

Keyword(s):

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Relationship Analysis ◽

Structure Activity ◽

Cation Permeability

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In-silico Comparative Study and Quantitative Structure-activity Relationship Analysis of Some Structural Physiochemical Descriptors of Elvitegravir Analogs

Journal of Young Pharmacists ◽

10.4103/0975-1483.83776 ◽

2011 ◽

Vol 3 (3) ◽

pp. 246-249 ◽

Cited By ~ 3

Author(s):

R. Satpathy ◽

S. Ghosh

Keyword(s):

Comparative Study ◽

In Silico ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Relationship Analysis ◽

Structure Activity

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Quantitative Structure-Activity Relationship Analysis of the Substituent Effects on the Binding Affinity of Derivatives of Trimetazidine

Arzneimittelforschung ◽

10.1055/s-0031-1296930 ◽

2011 ◽

Vol 54 (01) ◽

pp. 9-14

Author(s):

Svetoslav Slavov ◽

Maria Djunlieva ◽

Sonia Ilieva ◽

Boris Galabov

Keyword(s):

Binding Affinity ◽

Substituent Effects ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Relationship Analysis ◽

Structure Activity ◽

Derivatives Of

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Antileishmanial Chalcones: Statistical Design, Synthesis, and Three-Dimensional Quantitative Structure−Activity Relationship Analysis

Journal of Medicinal Chemistry ◽

10.1021/jm980410m ◽

1998 ◽

Vol 41 (24) ◽

pp. 4819-4832 ◽

Cited By ~ 183

Author(s):

Simon Feldbæk Nielsen ◽

Søren Brøgger Christensen ◽

Gabriele Cruciani ◽

Arsalan Kharazmi ◽

Tommy Liljefors

Keyword(s):

Three Dimensional ◽

Statistical Design ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Design Synthesis ◽

Relationship Analysis ◽

Structure Activity

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ChemInform Abstract: Synthesis, Fungitoxicity and Quantitative Structure-Activity Relationship Analysis of O-Aryl O-Ethyl 2-Chloroethyl Phosphonates.

ChemInform ◽

10.1002/chin.199916173 ◽

2010 ◽

Vol 30 (16) ◽

pp. no-no

Author(s):

Atulya K. Panda ◽

N. K. Roy

Keyword(s):

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Relationship Analysis ◽

Structure Activity

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