Design, synthesis, testing, and quantitative structure-activity relationship analysis of substituted salicylaldehyde Schiff bases of 1-amino-3-hydroxyguanidine tosylate as new antiviral agents against coronavirus

Pou Hsiung Wang; James G. Keck; Eric J. Lien; Michael M. C. Lai

doi:10.1021/jm00164a023

Design, synthesis, testing, and quantitative structure-activity relationship analysis of substituted salicylaldehyde Schiff bases of 1-amino-3-hydroxyguanidine tosylate as new antiviral agents against coronavirus

Journal of Medicinal Chemistry ◽

10.1021/jm00164a023 ◽

1990 ◽

Vol 33 (2) ◽

pp. 608-614 ◽

Cited By ~ 115

Author(s):

Pou Hsiung Wang ◽

James G. Keck ◽

Eric J. Lien ◽

Michael M. C. Lai

Keyword(s):

Schiff Bases ◽

Antiviral Agents ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Design Synthesis ◽

Relationship Analysis ◽

Structure Activity

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Antileishmanial Chalcones: Statistical Design, Synthesis, and Three-Dimensional Quantitative Structure−Activity Relationship Analysis

Journal of Medicinal Chemistry ◽

10.1021/jm980410m ◽

1998 ◽

Vol 41 (24) ◽

pp. 4819-4832 ◽

Cited By ~ 183

Author(s):

Simon Feldbæk Nielsen ◽

Søren Brøgger Christensen ◽

Gabriele Cruciani ◽

Arsalan Kharazmi ◽

Tommy Liljefors

Keyword(s):

Three Dimensional ◽

Statistical Design ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Design Synthesis ◽

Relationship Analysis ◽

Structure Activity

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Synthesis, Biological Evaluation, and Quantitative Structure−Activity Relationship Analysis of New Schiff Bases of Hydroxysemicarbazide as Potential Antitumor Agents†

Journal of Medicinal Chemistry ◽

10.1021/jm010252q ◽

2002 ◽

Vol 45 (2) ◽

pp. 410-419 ◽

Cited By ~ 185

Author(s):

Shijun Ren ◽

Rubin Wang ◽

Kenichi Komatsu ◽

Patricia Bonaz-Krause ◽

Yegor Zyrianov ◽

...

Keyword(s):

Schiff Bases ◽

Antitumor Agents ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Biological Evaluation ◽

Activity Relationship ◽

Quantitative Structure ◽

Relationship Analysis ◽

Structure Activity ◽

Potential Antitumor

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Quantitative Structure-Activity Relationship Analysis of the Cation Permeability of the P2X2 Channel

Medicinal Chemistry ◽

10.2174/1573406053175210 ◽

2005 ◽

Vol 1 (2) ◽

pp. 109-115 ◽

Cited By ~ 3

Author(s):

Peter Mager ◽

Anje Weber ◽

Peter Illes

Keyword(s):

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Relationship Analysis ◽

Structure Activity ◽

Cation Permeability

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In-silico Comparative Study and Quantitative Structure-activity Relationship Analysis of Some Structural Physiochemical Descriptors of Elvitegravir Analogs

Journal of Young Pharmacists ◽

10.4103/0975-1483.83776 ◽

2011 ◽

Vol 3 (3) ◽

pp. 246-249 ◽

Cited By ~ 3

Author(s):

R. Satpathy ◽

S. Ghosh

Keyword(s):

Comparative Study ◽

In Silico ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Relationship Analysis ◽

Structure Activity

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Quantitative Structure-Activity Relationship Analysis of the Substituent Effects on the Binding Affinity of Derivatives of Trimetazidine

Arzneimittelforschung ◽

10.1055/s-0031-1296930 ◽

2011 ◽

Vol 54 (01) ◽

pp. 9-14

Author(s):

Svetoslav Slavov ◽

Maria Djunlieva ◽

Sonia Ilieva ◽

Boris Galabov

Keyword(s):

Binding Affinity ◽

Substituent Effects ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Relationship Analysis ◽

Structure Activity ◽

Derivatives Of

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Novel Pyrazole-4-acetohydrazide Derivatives Potentially Targeting Fungal Succinate Dehydrogenase: Design, Synthesis, Three-Dimensional Quantitative Structure–Activity Relationship, and Molecular Docking

Journal of Agricultural and Food Chemistry ◽

10.1021/acs.jafc.1c03399 ◽

2021 ◽

Author(s):

Xiaobin Wang ◽

Mengqi Wang ◽

Ling Han ◽

Fei Jin ◽

Jian Jiao ◽

...

Keyword(s):

Molecular Docking ◽

Succinate Dehydrogenase ◽

Three Dimensional ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Design Synthesis ◽

Structure Activity

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Design, Synthesis and Quantitative Structure-Activity Relationship Study of N-(3-Oxo-3,4-dihydro-2H-benzo(1,4)oxazine-7-carbonyl)guanidine Derivatives as Potent Na/H Exchange Inhibitors.

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.45.1975 ◽

1997 ◽

Vol 45 (12) ◽

pp. 1975-1983 ◽

Cited By ~ 3

Author(s):

Takeshi YAMAMOTO ◽

Manabu HORI ◽

Ikuo WATANABE ◽

Hisayoshi TSUTSUI ◽

Kengo HARADA ◽

...

Keyword(s):

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Design Synthesis ◽

Guanidine Derivatives ◽

Structure Activity ◽

Relationship Study

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ChemInform Abstract: Synthesis, Fungitoxicity and Quantitative Structure-Activity Relationship Analysis of O-Aryl O-Ethyl 2-Chloroethyl Phosphonates.

ChemInform ◽

10.1002/chin.199916173 ◽

2010 ◽

Vol 30 (16) ◽

pp. no-no

Author(s):

Atulya K. Panda ◽

N. K. Roy

Keyword(s):

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Relationship Analysis ◽

Structure Activity

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The use of ladder particle swarm optimisation for quantitative structure–activity relationship analysis of human immunodeficiency virus-1 integrase inhibitors

Molecular Simulation ◽

10.1080/08927022.2011.586347 ◽

2011 ◽

Vol 37 (15) ◽

pp. 1221-1233 ◽

Cited By ~ 3

Author(s):

Mehdi Jalali-Heravi ◽

Heshmatollah Ebrahimi-Najafabadi

Keyword(s):

Human Immunodeficiency Virus ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Integrase Inhibitors ◽

Relationship Analysis ◽

Structure Activity ◽

Immunodeficiency Virus ◽

Human Immunodeficiency Virus 1

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Proposal of a New Binding Orientation for Non-Peptide AT1 Antagonists: Homology Modeling, Docking and Three-Dimensional Quantitative Structure−Activity Relationship Analysis

Journal of Medicinal Chemistry ◽

10.1021/jm060338p ◽

2006 ◽

Vol 49 (14) ◽

pp. 4305-4316 ◽

Cited By ~ 60

Author(s):

Tiziano Tuccinardi ◽

Vincenzo Calderone ◽

Simona Rapposelli ◽

Adriano Martinelli

Keyword(s):

Homology Modeling ◽

Three Dimensional ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Relationship Analysis ◽

Structure Activity ◽

At1 Antagonists ◽

Binding Orientation

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