Stereochemical studies on the cytochrome P-450 catalyzed oxidation of (S)-nicotine to the (S)-nicotine .DELTA.1'(5')-iminium species

Lisa A. Peterson; Anthony Trevor; Neal Castagnoli

doi:10.1021/jm00385a004

Stereochemical studies on the cytochrome P-450 catalyzed oxidation of (S)-nicotine to the (S)-nicotine .DELTA.1'(5')-iminium species

Journal of Medicinal Chemistry ◽

10.1021/jm00385a004 ◽

1987 ◽

Vol 30 (2) ◽

pp. 249-254 ◽

Cited By ~ 46

Author(s):

Lisa A. Peterson ◽

Anthony Trevor ◽

Neal Castagnoli

Keyword(s):

Cytochrome P 450 ◽

Catalyzed Oxidation

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Enzymatic monooxygenation of halogen atoms: cytochrome P-450 catalyzed oxidation of iodobenzene by iodosobenzene

Journal of the American Chemical Society ◽

10.1021/ja00545a062 ◽

1980 ◽

Vol 102 (25) ◽

pp. 7615-7616 ◽

Cited By ~ 29

Author(s):

Leo T. Burka ◽

Alice Thorsen ◽

F. Peter Guengerich

Keyword(s):

Halogen Atoms ◽

Cytochrome P 450 ◽

Catalyzed Oxidation

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Kinetic Isotope Effects in Cytochrome P-450-Catalyzed Oxidation Reactions. II. Interactions of Cytochrome P-450 with Substrates and Nadph-Cytochrome % MathType!MTEF!2!1!+-% feaagCart1ev2aaatCvAUfeBSjuyZL2yd9gzLbvyNv2CaerbuLwBLn% hiov2DGi1BTfMBaeXatLxBI9gBaerbd9wDYLwzYbItLDharqqtubsr% 4rNCHbGeaGqiVu0Je9sqqrpepC0xbbL8F4rqqrFfpeea0xe9Lq-Jc9% vqaqpepm0xbba9pwe9Q8fs0-yqaqpepae9pg0FirpepeKkFr0xfr-x% fr-xb9adbaqaaeGaciGaaiaabeqaamaabaabaaGcbaGabm4yayaaDa% aaaa!3700! $$\underset{\raise0.3em\hbox{$\smash{\scriptscriptstyle-}$}}{c} $$ Reductase

Alcohol and Aldehyde Metabolizing Systems-IV ◽

10.1007/978-1-4757-1419-7_11 ◽

1980 ◽

pp. 95-108 ◽

Cited By ~ 1

Author(s):

Anthony Y. H. Lu ◽

Gerald T. Miwa ◽

Susan B. West ◽

Barbara J. Hodshon ◽

William A. Garland

Keyword(s):

Isotope Effects ◽

Kinetic Isotope Effects ◽

Oxidation Reactions ◽

Nadph Cytochrome ◽

Kinetic Isotope ◽

Cytochrome P 450 ◽

Catalyzed Oxidation

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The cytochrome P-450 catalyzed oxidation of 1-methylcyclohexene. Competition between hydroxylation and epoxidation and absolute stereochemistry of the epoxidation

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/s0960-894x(00)80244-9 ◽

1991 ◽

Vol 1 (2) ◽

pp. 121-124 ◽

Cited By ~ 2

Author(s):

Giuseppe Bellucci ◽

Cinzia Chiappe ◽

Franco Marioni ◽

Pier Giovanni Gervasi ◽

Annalisa Lippi

Keyword(s):

Cytochrome P 450 ◽

Catalyzed Oxidation ◽

Absolute Stereochemistry

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The Role of Cytochrome P-450 in the Hydroperoxide-Catalyzed Oxidation of Alcohols by Rat-Liver Microsomes

European Journal of Biochemistry ◽

10.1111/j.1432-1033.1977.tb11658.x ◽

1977 ◽

Vol 77 (1) ◽

pp. 201-208 ◽

Cited By ~ 21

Author(s):

Anver D. RAHIMTULA ◽

Peter J. O'BRIEN

Keyword(s):

Rat Liver ◽

Liver Microsomes ◽

Rat Liver Microsomes ◽

Oxidation Of Alcohols ◽

Cytochrome P 450 ◽

Catalyzed Oxidation

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Kinetic isotope effects in cytochrome P-450-catalyzed oxidation reactions. Intermolecular and intramolecular deuterium isotope effects during the N-demethylation of N,N-dimethylphentermine.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)43699-x ◽

1980 ◽

Vol 255 (13) ◽

pp. 6049-6054 ◽

Cited By ~ 3

Author(s):

G.T. Miwa ◽

W.A. Garland ◽

B.J. Hodshon ◽

A.Y. Lu ◽

D.B. Northrop

Keyword(s):

Isotope Effects ◽

Kinetic Isotope Effects ◽

Oxidation Reactions ◽

Kinetic Isotope ◽

Deuterium Isotope Effects ◽

Cytochrome P 450 ◽

Catalyzed Oxidation

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Kinetic isotope effects on cytochrome P-450-catalyzed oxidation reactions. Evidence for the irreversible formation of an activated oxygen intermediate of cytochrome P-448.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)43249-2 ◽

1984 ◽

Vol 259 (5) ◽

pp. 3005-3010 ◽

Cited By ~ 4

Author(s):

N Harada ◽

G T Miwa ◽

J S Walsh ◽

A Y Lu

Keyword(s):

Isotope Effects ◽

Kinetic Isotope Effects ◽

Oxidation Reactions ◽

Kinetic Isotope ◽

Activated Oxygen ◽

Cytochrome P 450 ◽

Catalyzed Oxidation

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Radical Intermediates in the Cytochrome P-450-Catalyzed Oxidation of Aliphatic Hydrocarbons

Drug Metabolism Reviews ◽

10.3109/03602538909103535 ◽

1989 ◽

Vol 20 (2-4) ◽

pp. 183-191 ◽

Cited By ~ 11

Author(s):

Paul R. Ortiz De Montellano ◽

Ralph A. Stearns

Keyword(s):

Aliphatic Hydrocarbons ◽

Radical Intermediates ◽

Cytochrome P 450 ◽

Catalyzed Oxidation

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Quantum chemical simulation of the cytochrome P 450 catalyzed oxidation and toxicity of benzene derivatives

10.1063/1.47657 ◽

1995 ◽

Author(s):

P. N. D’yachkov

Keyword(s):

Quantum Chemical ◽

Benzene Derivatives ◽

Quantum Chemical Simulation ◽

Chemical Simulation ◽

Cytochrome P 450 ◽

Catalyzed Oxidation

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KINETIC ISOTOPE EFFECTS IN CYTOCHROME P-450-CATALYZED OXIDATION REACTIONS. I. SUBSTRATE - CYTOCHROME P-450 INTERACTIONS

Microsomes, Drug Oxidations and Chemical Carcinogenesis ◽

10.1016/b978-0-12-187701-9.50071-1 ◽

1980 ◽

pp. 363-366 ◽

Cited By ~ 1

Author(s):

Gerald T. Miwa ◽

Jonathan S. Zweig ◽

John S.A. Walsh ◽

Anthony Y.H. Lu

Keyword(s):

Isotope Effects ◽

Kinetic Isotope Effects ◽

Oxidation Reactions ◽

Kinetic Isotope ◽

Cytochrome P 450 ◽

Catalyzed Oxidation

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Kinetic isotope effects on cytochrome P-450-catalyzed oxidation reactions. The oxidative O-dealkylation of 7-ethoxycoumarin.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)43248-0 ◽

1984 ◽

Vol 259 (5) ◽

pp. 3000-3004

Author(s):

G T Miwa ◽

J S Walsh ◽

A Y Lu

Keyword(s):

Isotope Effects ◽

Kinetic Isotope Effects ◽

Oxidation Reactions ◽

Kinetic Isotope ◽

Cytochrome P 450 ◽

Catalyzed Oxidation

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