Irreversible Enzyme Inhibitors. CV.1,2Differential Irreversible Inhibition of Vertebrate Dihydrofolic Reductases by Derivatives of 4,6-Diamino-1,2-dihydro-2,2-dimethyl-1-phenyl-s-triazines Substituted with a Terminal Sulfonyl Fluoride3

B. R. Baker; Gerhardus J. Lourens

doi:10.1021/jm00318a029

Irreversible Enzyme Inhibitors. CV.1,2Differential Irreversible Inhibition of Vertebrate Dihydrofolic Reductases by Derivatives of 4,6-Diamino-1,2-dihydro-2,2-dimethyl-1-phenyl-s-triazines Substituted with a Terminal Sulfonyl Fluoride3

Journal of Medicinal Chemistry ◽

10.1021/jm00318a029 ◽

1967 ◽

Vol 10 (6) ◽

pp. 1113-1122 ◽

Cited By ~ 28

Author(s):

B. R. Baker ◽

Gerhardus J. Lourens

Keyword(s):

Enzyme Inhibitors ◽

Irreversible Inhibition ◽

Derivatives Of

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5476847 Derivatives of phosphinic acid useful as endothelin converting enzyme inhibitors

Biotechnology Advances ◽

10.1016/s0734-9750(97)88331-0 ◽

1997 ◽

Vol 15 (1) ◽

pp. 204

Keyword(s):

Enzyme Inhibitors ◽

Phosphinic Acid ◽

Converting Enzyme ◽

Converting Enzyme Inhibitors ◽

Endothelin Converting Enzyme ◽

Derivatives Of

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Molecular and crystal structures of MDL27,467A hydrochloride and quinapril hydrochloride, two ester derivatives of potent angiotensin converting enzyme inhibitors

Journal of Medicinal Chemistry ◽

10.1021/jm00106a005 ◽

1991 ◽

Vol 34 (2) ◽

pp. 511-517 ◽

Cited By ~ 10

Author(s):

Roland J. Hausin ◽

Penelope W. Codding

Keyword(s):

Angiotensin Converting Enzyme ◽

Crystal Structures ◽

Enzyme Inhibitors ◽

Angiotensin Converting Enzyme Inhibitors ◽

Converting Enzyme ◽

Converting Enzyme Inhibitors ◽

Molecular And Crystal Structures ◽

Derivatives Of ◽

Quinapril Hydrochloride

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Design, Synthesis, and Evaluation of Acyclic C-Nucleoside and N-Methylated Derivatives of the Ribitylaminopyrimidine Substrate of Lumazine Synthase as Potential Enzyme Inhibitors and Mechanistic Probes.

ChemInform ◽

10.1002/chin.200508222 ◽

2005 ◽

Vol 36 (8) ◽

Author(s):

Jinhua Chen ◽

Thota Sambaiah ◽

Boris Illarionov ◽

Markus Fischer ◽

Adelbert Bacher ◽

...

Keyword(s):

Enzyme Inhibitors ◽

Design Synthesis ◽

Lumazine Synthase ◽

Derivatives Of

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Irreversible enzyme inhibitors. 181. Inhibition of brain choline acetyltransferase by derivatives of 4-stilbazole

Journal of Medicinal Chemistry ◽

10.1021/jm00286a011 ◽

1971 ◽

Vol 14 (4) ◽

pp. 315-322 ◽

Cited By ~ 37

Author(s):

Bernard Randall Baker ◽

Raymond E. Gibson

Keyword(s):

Choline Acetyltransferase ◽

Enzyme Inhibitors ◽

Derivatives Of

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Irreversible enzyme inhibitors. CXXXIV. Effect of ring substitution on the selective irreversible inhibition of dihydrofolic reductase from L1210 mouse leukemia and liver by 2,4-diamino-5-(3,4-dichlorophenyl)-6-[p-(m-fluorosulfonylphenylureido)phenoxymethyl]pyrimidine

Journal of Medicinal Chemistry ◽

10.1021/jm00301a019 ◽

1969 ◽

Vol 12 (1) ◽

pp. 74-78 ◽

Cited By ~ 2

Author(s):

Bernard Randall Baker ◽

Nicolaas Vermeulen

Keyword(s):

Enzyme Inhibitors ◽

Mouse Leukemia ◽

Irreversible Inhibition ◽

L1210 Mouse Leukemia

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Irreversible enzyme inhibitors. CLVIII. Effect of bridge modification on the selective irreversible inhibition of a dihydrofolic reductase from L1210 mouse leukemia and liver by 2,4-diamino-5-(3,4-dichlorophenyl)-6-[p-[m-(fluorosulfonyl)benzamidomethyl]phenoxymethyl]pyrimidine. II

Journal of Medicinal Chemistry ◽

10.1021/jm00304a028 ◽

1969 ◽

Vol 12 (4) ◽

pp. 684-688 ◽

Cited By ~ 1

Author(s):

Bernard Randall Baker ◽

Nicolaas M. J. Vermeulen

Keyword(s):

Enzyme Inhibitors ◽

Mouse Leukemia ◽

Irreversible Inhibition ◽

L1210 Mouse Leukemia

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Irreversible enzyme inhibitors. CLXXV. Irreversible inhibition of purifed dihydrofolic reductase

Journal of Medicinal Chemistry ◽

10.1021/jm00300a028 ◽

1970 ◽

Vol 13 (6) ◽

pp. 1143-1148 ◽

Cited By ~ 12

Author(s):

Bernard Randall Baker ◽

Nicolaas M. J. Vermeulen

Keyword(s):

Enzyme Inhibitors ◽

Irreversible Inhibition

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Irreversible enzyme inhibitors. CXXXV. Effect of ring substitution on the selective irreversible inhibition of dihydrofolic reductase from L1210 mouse leukemia and liver by 2,4-diamino-5-(3,4-dichlorophenyl)-6-[p-(p-fluorosulfonylphenylureido)phenoxymethyl]pyrimidine

Journal of Medicinal Chemistry ◽

10.1021/jm00301a020 ◽

1969 ◽

Vol 12 (1) ◽

pp. 79-81 ◽

Cited By ~ 1

Author(s):

Bernard Randall Baker ◽

Nicolaas M. J. Vermeulen

Keyword(s):

Enzyme Inhibitors ◽

Mouse Leukemia ◽

Irreversible Inhibition ◽

L1210 Mouse Leukemia

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Irreversible enzyme inhibitors. XCIV. inhibition of dihydrofolic reductase with derivatives of 2,6-diaminopurines

Journal of Heterocyclic Chemistry ◽

10.1002/jhet.5570040209 ◽

1967 ◽

Vol 4 (2) ◽

pp. 216-223 ◽

Cited By ~ 4

Author(s):

B. R. Baker ◽

Daniel V. Santi

Keyword(s):

Enzyme Inhibitors ◽

Derivatives Of

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ChemInform Abstract: DIASTEREOMERIC 6-DESOXY-6-SPIRO-α-METHYLENE-Γ-BUTYROLACTONE DERIVATIVES OF NALTREXONE AND OXYMORPHONE. SELECTIVE IRREVERSIBLE INHIBITION OF NALTREXONE BINDING IN AN OPIOID RECEPTOR PREPARATION BY A CONFORMATIONALLY RESTRICTED MICHAEL

Chemischer Informationsdienst ◽

10.1002/chin.198523209 ◽

1985 ◽

Vol 16 (23) ◽

Author(s):

G. A. KOOLPE ◽

W. L. NELSON ◽

T. L. GIOANNINI ◽

L. ANGEL ◽

E. J. SIMON

Keyword(s):

Opioid Receptor ◽

Conformationally Restricted ◽

Irreversible Inhibition ◽

Derivatives Of

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