Irreversible enzyme inhibitors. CXVIII. Hydrophobic bonding to dihydrofolic reductase. 12. Further comparisons with the enzyme from Walker 256 rat tumor and rat liver

Bernard Randall Baker; Morris Alfred Johnson

doi:10.1021/jm00309a017

Irreversible enzyme inhibitors. CXVIII. Hydrophobic bonding to dihydrofolic reductase. 12. Further comparisons with the enzyme from Walker 256 rat tumor and rat liver

Journal of Medicinal Chemistry ◽

10.1021/jm00309a017 ◽

1968 ◽

Vol 11 (3) ◽

pp. 486-488 ◽

Cited By ~ 4

Author(s):

Bernard Randall Baker ◽

Morris Alfred Johnson

Keyword(s):

Rat Liver ◽

Enzyme Inhibitors ◽

Walker 256 ◽

Rat Tumor ◽

Hydrophobic Bonding

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Irreversible enzyme inhibitors. CXVII. Hydrophobic bonding to dihydrofolic reductase. II. Comparison of the enzyme from Walker 256, rat liver, and L1210 mouse leukemia

Journal of Medicinal Chemistry ◽

10.1021/jm00309a016 ◽

1968 ◽

Vol 11 (3) ◽

pp. 483-486 ◽

Cited By ~ 1

Author(s):

Bernard Randall Baker

Keyword(s):

Rat Liver ◽

Enzyme Inhibitors ◽

Mouse Leukemia ◽

L1210 Mouse Leukemia ◽

Walker 256 ◽

Hydrophobic Bonding

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Irreversible enzyme inhibitors. CLXXI. Inhibition of FUDR [5-fluoro-2'-deoxyuridine] phosphorylase from Walker 256 rat tumor by 5-substituted uracils

Journal of Medicinal Chemistry ◽

10.1021/jm00297a029 ◽

1970 ◽

Vol 13 (3) ◽

pp. 461-467 ◽

Cited By ~ 29

Author(s):

Bernard Randall Baker ◽

James L. Kelley

Keyword(s):

Enzyme Inhibitors ◽

Walker 256 ◽

Substituted Uracils ◽

Rat Tumor

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ChemInform Abstract: IRREVERSIBLE ENZYME INHIBITORS. 202. CANDIDATE ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS OF 5-FLUORO-2′-DEOXYURIDINE PHOSPHORYLASE FROM WALKER 256 RAT TUMOR DERIVED FROM 1-BENZYL-5-(3-ETHOXYBENZYL)URACIL

Chemischer Informationsdienst ◽

10.1002/chin.198241232 ◽

1982 ◽

Vol 13 (41) ◽

Author(s):

J. L. KELLEY ◽

B. R. BAKER

Keyword(s):

Active Site ◽

Enzyme Inhibitors ◽

Irreversible Inhibitors ◽

Walker 256 ◽

Rat Tumor

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Irreversible enzyme inhibitors. CLXIX. Inhibition of FUDR [5-fluoro-2'-deoxyuridine] phosphorylase from Walker 256 rat tumor by 6-substituted uracils

Journal of Medicinal Chemistry ◽

10.1021/jm00297a027 ◽

1970 ◽

Vol 13 (3) ◽

pp. 456-458 ◽

Cited By ~ 8

Author(s):

Bernard Randall Baker ◽

James L. Kelley

Keyword(s):

Enzyme Inhibitors ◽

Walker 256 ◽

Substituted Uracils ◽

Rat Tumor

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Irreversible enzyme inhibitors. CLXX. Inhibition of FUDR [5-fluoro-2'-deoxyuridine] phosphorylase from Walker 256 rat tumor by 1-substituted uracils

Journal of Medicinal Chemistry ◽

10.1021/jm00297a028 ◽

1970 ◽

Vol 13 (3) ◽

pp. 458-461 ◽

Cited By ~ 6

Author(s):

Bernard Randall Baker ◽

James L. Kelley

Keyword(s):

Enzyme Inhibitors ◽

Walker 256 ◽

Substituted Uracils ◽

Rat Tumor

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Irreversible enzyme inhibitors. 202. Candidate active-site-directed irreversible inhibitors of 5-fluoro-2'-deoxyuridine phosphorylase from Walker 256 rat tumor derived from 1-benzyl-5-(3-ethoxybenzyl)uracil

Journal of Medicinal Chemistry ◽

10.1021/jm00347a022 ◽

1982 ◽

Vol 25 (5) ◽

pp. 600-603 ◽

Cited By ~ 12

Author(s):

James L. Kelley ◽

B. R. Baker

Keyword(s):

Active Site ◽

Enzyme Inhibitors ◽

Irreversible Inhibitors ◽

Walker 256 ◽

Rat Tumor

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Irreversible enzyme inhibitors. CXXX. Cytosine nucleoside deaminase. 1. Hydrophobic bonding with monosubstituted uracils

Journal of Medicinal Chemistry ◽

10.1021/jm00310a010 ◽

1968 ◽

Vol 11 (4) ◽

pp. 682-686 ◽

Cited By ~ 8

Author(s):

Bernard R. Baker ◽

James L. Kelley

Keyword(s):

Enzyme Inhibitors ◽

Hydrophobic Bonding

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Irreversible enzyme inhibitors LXXXVII. Hydrophobic bonding to dihydrofolic reductase IX. Mode of binding of m-aryloxyalkyl groups on 4, 6-diamino-1,2-dihydro-2, 2-dimethyl-1-phenyl-s-triazine

Journal of Pharmaceutical Sciences ◽

10.1002/jps.2600560717 ◽

1967 ◽

Vol 56 (7) ◽

pp. 871-875 ◽

Cited By ~ 3

Author(s):

B.R. Baker ◽

Gerhardus J. Lourens

Keyword(s):

Enzyme Inhibitors ◽

Hydrophobic Bonding

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Irreversible enzyme inhibitors. CXXXI. Cytosine nucleoside deaminase. 2. Hydrophobic bonding with disubstituted uracils and cytosines

Journal of Medicinal Chemistry ◽

10.1021/jm00310a011 ◽

1968 ◽

Vol 11 (4) ◽

pp. 686-690 ◽

Cited By ~ 12

Author(s):

B. R. Baker ◽

James L. Kelley

Keyword(s):

Enzyme Inhibitors ◽

Hydrophobic Bonding

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Irreversible enzyme inhibitors. CXXII. Nature and dimensions of the hydrophobic bonding region of guanine deaminase and xanthine oxidase

Journal of Medicinal Chemistry ◽

10.1021/jm00310a002 ◽

1968 ◽

Vol 11 (4) ◽

pp. 644-649 ◽

Cited By ~ 14

Author(s):

B. R. Baker ◽

William F. Wood

Keyword(s):

Xanthine Oxidase ◽

Enzyme Inhibitors ◽

Guanine Deaminase ◽

Hydrophobic Bonding

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