Structure-activity relationships of antibacterial 6,7- and 7,8-disubstituted 1-alkyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acids

Hiroshi Koga; Akira Itoh; Satoshi Murayama; Seigo Suzue; Tsutomu Irikura

doi:10.1021/jm00186a014

Structure-activity relationships of antibacterial 6,7- and 7,8-disubstituted 1-alkyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acids

Journal of Medicinal Chemistry ◽

10.1021/jm00186a014 ◽

1980 ◽

Vol 23 (12) ◽

pp. 1358-1363 ◽

Cited By ~ 339

Author(s):

Hiroshi Koga ◽

Akira Itoh ◽

Satoshi Murayama ◽

Seigo Suzue ◽

Tsutomu Irikura

Keyword(s):

Carboxylic Acids ◽

Structure Activity Relationships ◽

Structure Activity

Download Full-text

Fluoronaphthyridines as antibacterial agents. 4. Synthesis and structure-activity relationships of 5-substituted 6-fluoro-7-(cycloalkylamino)-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acids

Journal of Medicinal Chemistry ◽

10.1021/jm00081a013 ◽

1992 ◽

Vol 35 (3) ◽

pp. 518-525 ◽

Cited By ~ 52

Author(s):

D. Bouzard ◽

P. Di Cesare ◽

M. Essiz ◽

J. P. Jacquet ◽

B. Ledoussal ◽

...

Keyword(s):

Carboxylic Acids ◽

Antibacterial Agents ◽

Structure Activity Relationships ◽

Structure Activity

Download Full-text

Synthesis, Biological Evaluation, and Structure−Activity Relationships of 3-Acylindole-2-carboxylic Acids as Inhibitors of the Cytosolic Phospholipase A2

Journal of Medicinal Chemistry ◽

10.1021/jm960863w ◽

1997 ◽

Vol 40 (17) ◽

pp. 2694-2705 ◽

Cited By ~ 20

Author(s):

Matthias Lehr

Keyword(s):

Phospholipase A2 ◽

Carboxylic Acids ◽

Biological Evaluation ◽

Cytosolic Phospholipase A2 ◽

Structure Activity Relationships ◽

Cytosolic Phospholipase ◽

Structure Activity

Download Full-text

Studies on .BETA.-lactam antibiotics. VIII. Structure-activity relationships of 7.BETA.-((Z)-2-carboxymethoxyimino-2-arylacetamido)-3-cephem-4-carboxylic acids.

The Journal of Antibiotics ◽

10.7164/antibiotics.38.1068 ◽

1985 ◽

Vol 38 (8) ◽

pp. 1068-1076 ◽

Cited By ~ 6

Author(s):

HIDEAKI YAMANAKA ◽

HISASHI TAKASUGI ◽

TAKASHI MASUGI ◽

HIROMU KOCHI ◽

KENJI MIYAI ◽

...

Keyword(s):

Carboxylic Acids ◽

Beta Lactam ◽

Structure Activity Relationships ◽

Beta Lactam Antibiotics ◽

Structure Activity

Download Full-text

Orally active cephalosporins. III. Synthesis and structure-activity relationships of new 3-heterocyclicthiomethylthio-7.BETA.-((Z)-2(2-aminothiazol-4-yl)-2-hydroxyiminoacetamido)-3-cephem-4-carboxylic acids.

The Journal of Antibiotics ◽

10.7164/antibiotics.46.316 ◽

1993 ◽

Vol 46 (2) ◽

pp. 316-330 ◽

Cited By ~ 2

Author(s):

MASAHARU KUME ◽

TADATOSHI KUBOTA ◽

YASUO KIMURA ◽

HIROMU NAKASHIMIZU ◽

KIYOSHI MOTOKAWA

Keyword(s):

Carboxylic Acids ◽

Structure Activity Relationships ◽

Structure Activity ◽

Orally Active

Download Full-text

Structure–activity relationships on the odor detectability of homologous carboxylic acids by humans

Experimental Brain Research ◽

10.1007/s00221-010-2430-0 ◽

2010 ◽

Vol 207 (1-2) ◽

pp. 75-84 ◽

Cited By ~ 21

Author(s):

J. Enrique Cometto-Muñiz ◽

Michael H. Abraham

Keyword(s):

Carboxylic Acids ◽

Structure Activity Relationships ◽

Structure Activity

Download Full-text

ChemInform Abstract: OVERCROWDING FACTORS MOSQUITO LARVAE PART 6, STRUCTURE-ACTIVITY-RELATIONSHIPS OF 2-SUBSTITUTED ALIPHATIC CARBOXYLIC ACIDS AGAINST MOSQUITO LARVAE

Chemischer Informationsdienst ◽

10.1002/chin.197517199 ◽

1975 ◽

Vol 6 (17) ◽

pp. no-no

Author(s):

Y. S. HWANG ◽

M. S. MULLA ◽

J. R. ARIAS

Keyword(s):

Carboxylic Acids ◽

Mosquito Larvae ◽

Structure Activity Relationships ◽

Structure Activity ◽

Aliphatic Carboxylic Acids

Download Full-text

ChemInform Abstract: Studies on β-Lactam Antibiotics for Medicinal Purpose. Part 17. Synthesis and Structure-Activity Relationships of 7β-[D(-)-α-Amino-α-(4-hydroxyphenyl)acetamido]-3-substituted Methyl-3-cephem-4-carboxylic Acids.

Chemischer Informationsdienst ◽

10.1002/chin.198652326 ◽

1986 ◽

Vol 17 (52) ◽

Author(s):

H. SADAKI ◽

H. IMAIZUMI ◽

T. INABA ◽

T. HIRAKAWA ◽

Y. MUROTANI ◽

...

Keyword(s):

Carboxylic Acids ◽

Medicinal Purpose ◽

Structure Activity Relationships ◽

Structure Activity

Download Full-text

Semisynthetic Cephalosporins. III. 1Synthesis and Structure Activity Relationships of Novel Orally Active 7-[4-Hydroxy-3-(Substituted Methyl)phenyl]-Acetamido-3-Cephem-4-Carboxylic Acids

Natural Sulfur Compounds ◽

10.1007/978-1-4613-3045-5_46 ◽

1980 ◽

pp. 505-510

Author(s):

Abraham Nudelman ◽

Abraham Patchornick ◽

Eva Karoly-Hafely ◽

Frida Braun ◽

Richard C. Erickson

Keyword(s):

Carboxylic Acids ◽

Structure Activity Relationships ◽

Structure Activity ◽

Orally Active ◽

Methyl Phenyl

Download Full-text

Retinobenzoic acids. 3. Structure-activity relationships of retinoidal azobenzene-4-carboxylic acids and stilbene-4-carboxylic acids

Journal of Medicinal Chemistry ◽

10.1021/jm00125a027 ◽

1989 ◽

Vol 32 (5) ◽

pp. 1098-1108 ◽

Cited By ~ 35

Author(s):

Hiroyuki Kagechika ◽

Toshiyuki Himi ◽

Koushi Namikawa ◽

Emiko Kawachi ◽

Yuichi Hashimoto ◽

...

Keyword(s):

Carboxylic Acids ◽

Structure Activity Relationships ◽

Structure Activity

Download Full-text

Structure–Activity relationships of 2-substituted 5,7-Diarylcyclopenteno[1,2-b]pyridine-6-carboxylic acids as a novel class of endothelin receptor antagonists

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/s0960-894x(02)00663-7 ◽

2002 ◽

Vol 12 (21) ◽

pp. 3041-3045 ◽

Cited By ~ 7

Author(s):

Kenji Niiyama ◽

Hirobumi Takahashi ◽

Toshio Nagase ◽

Hisaki Kojima ◽

Yuka Amano ◽

...

Keyword(s):

Carboxylic Acids ◽

Endothelin Receptor Antagonists ◽

Endothelin Receptor ◽

Receptor Antagonists ◽

Structure Activity Relationships ◽

Structure Activity

Download Full-text