Synthesis of bioactive compounds. Substituted biphenyls as juvenile hormone mimics

1977 ◽  
Vol 25 (1) ◽  
pp. 213-214 ◽  
Author(s):  
George P. Nilles ◽  
Matthew J. Zabik ◽  
Richard V. Connin ◽  
Robert D. Schuetz
Keyword(s):  
Juvenile Hormone ◽  
Bioactive Compounds ◽  
Juvenile Hormone Mimics

Synthesis of Bioactive Compounds. A Structure-Activity Study of Aryl Terpenes as Juvenile Hormone Mimics

1976 ◽  
Vol 24 (6) ◽  
pp. 1256-1256
Author(s):  
George P. Nilles ◽  
Matthew J. Zabik ◽  
Richard V. Connin ◽  
Robert D. Schuetz
Keyword(s):  
Juvenile Hormone ◽  
Bioactive Compounds ◽  
Structure Activity ◽  
Juvenile Hormone Mimics

Synthesis of bioactive compounds. A structure-activity study of aryl terpenes as juvenile hormone mimics

1976 ◽  
Vol 24 (4) ◽  
pp. 699-708 ◽  
Author(s):  
George P. Nilles ◽  
Matthew J. Zabik ◽  
Richard V. Connin ◽  
Robert D. Schuetz
Keyword(s):  
Juvenile Hormone ◽  
Bioactive Compounds ◽  
Structure Activity ◽  
Juvenile Hormone Mimics

Insect juvenile hormone mimics: A structural basis for gonadotropic activity in a cockroach and a moth

1975 ◽  
Vol 21 (2) ◽  
pp. 463-469 ◽  
Author(s):  
Paul Sroka ◽  
Robert H. Barth ◽  
Lawrence I. Gilbert ◽  
Gerardus B. Staal
Keyword(s):  
Juvenile Hormone ◽  
Structural Basis ◽  
Gonadotropic Activity ◽  
Juvenile Hormone Mimics

Effects of juvenile hormone mimics on the codling moth Cydia Pomonella (L.) (Lep., Olethreutidae)

1973 ◽  
Vol 63 (1) ◽  
pp. 7-16 ◽  
Author(s):  
I. Gelbič ◽  
F. Sehnal
Keyword(s):  
Juvenile Hormone ◽  
Laboratory Experiments ◽  
Cydia Pomonella ◽  
Codling Moth ◽  
The Other ◽  
Wide Range ◽  
Juvenile Hormone Analogues ◽  
Juvenile Hormone Mimics

AbstractLaboratory experiments with juvenile hormone analogues on Cydia pomonella (L.) showed that Cecropia C17 juvenile hormone (methyl 10,ll-epoxy-3,7,ll-trimethyl-2,6-dodecadienoate) was the most active of the 28 compounds tested. When applied to four-hour-old eggs at 0.1 μg/egg, the hormone caused 100% failure in embryogenesis, while the other compounds were at least five times less effective. Depending on the time since ecdysis and the dose, juvenile hormone mimics applied to last-instar larvae resulted in a wide range of intermediate forms. Against three-day-old last-instar larvae, the Cecropia C17 hormone gave 100% inhibition of development at a dose of 1 μg/larva, while three other compounds (methyl 10,11-epoxy-3,7,11-trimethyl-2,6-dodecadienoate, ethyl 11-chloro-3,7,11-trimethyl-2-dodecenoate and ethyl 3,7,11-tri-methyl-2,4-dodecadienoate) gave the same effect at 2–5 μg/larva. Against newly emerged adults, the last two compounds at 10–50 μg/insect reduced fecundity and fertility to 0–81% and 0–50%, respectively, of their normal levels.

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