SAR and QSAR Modeling of Juvenile Hormone Mimics

2013 ◽  
pp. 159-188 ◽  
Keyword(s):  
Juvenile Hormone ◽  
Qsar Modeling ◽  
Juvenile Hormone Mimics

Insect juvenile hormone mimics: A structural basis for gonadotropic activity in a cockroach and a moth

1975 ◽  
Vol 21 (2) ◽  
pp. 463-469 ◽  
Author(s):  
Paul Sroka ◽  
Robert H. Barth ◽  
Lawrence I. Gilbert ◽  
Gerardus B. Staal
Keyword(s):  
Juvenile Hormone ◽  
Structural Basis ◽  
Gonadotropic Activity ◽  
Juvenile Hormone Mimics

Effects of juvenile hormone mimics on the codling moth Cydia Pomonella (L.) (Lep., Olethreutidae)

1973 ◽  
Vol 63 (1) ◽  
pp. 7-16 ◽  
Author(s):  
I. Gelbič ◽  
F. Sehnal
Keyword(s):  
Juvenile Hormone ◽  
Laboratory Experiments ◽  
Cydia Pomonella ◽  
Codling Moth ◽  
The Other ◽  
Wide Range ◽  
Juvenile Hormone Analogues ◽  
Juvenile Hormone Mimics

AbstractLaboratory experiments with juvenile hormone analogues on Cydia pomonella (L.) showed that Cecropia C17 juvenile hormone (methyl 10,ll-epoxy-3,7,ll-trimethyl-2,6-dodecadienoate) was the most active of the 28 compounds tested. When applied to four-hour-old eggs at 0.1 μg/egg, the hormone caused 100% failure in embryogenesis, while the other compounds were at least five times less effective. Depending on the time since ecdysis and the dose, juvenile hormone mimics applied to last-instar larvae resulted in a wide range of intermediate forms. Against three-day-old last-instar larvae, the Cecropia C17 hormone gave 100% inhibition of development at a dose of 1 μg/larva, while three other compounds (methyl 10,11-epoxy-3,7,11-trimethyl-2,6-dodecadienoate, ethyl 11-chloro-3,7,11-trimethyl-2-dodecenoate and ethyl 3,7,11-tri-methyl-2,4-dodecadienoate) gave the same effect at 2–5 μg/larva. Against newly emerged adults, the last two compounds at 10–50 μg/insect reduced fecundity and fertility to 0–81% and 0–50%, respectively, of their normal levels.

INSECT DEVELOPMENTAL INHIBITORS: EFFECT OF REDUCTION AND DELAY CAUSED BY JUVENILE HORMONE MIMICS ON THE PRODUCTION OF WINGED MIGRANTS OF MYZUS PERSICAE (HEMIPTERA: APHIDIDAE) ON PEACH TREES

1973 ◽  
Vol 105 (5) ◽  
pp. 761-765 ◽  
Author(s):  
George Tamaki
Keyword(s):  
Juvenile Hormone ◽  
Natural Enemies ◽  
Myzus Persicae ◽  
Green Peach Aphid ◽  
Economic Gain ◽  
Subsequent Reduction ◽  
Peach Trees ◽  
Juvenile Hormone Mimics

AbstractInsect developmental inhibitors applied to colonies of the green peach aphid, Myzus persicae (Sulzer), on peach trees in early May reduced the production of winged migrants as much as 75% and delayed migration for as long as 15 days. However, these compounds affected mainly the alatoid nymphs and not the reproductive adults; therefore, apterous aphids would be available as prey to the natural enemies that are present on peach trees in the spring. A reduction in the number of aphid migrants and a delay in their migration from peach trees would result in a subsequent reduction in the number of aphids produced on diseased secondary hosts and a delay in the migration of these aphids to host crops. In most cases, this would result in an increase in yield and an economic gain to the growers.

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