Competitive Reduction of Perferrylmyoglobin Radicals by Protein Thiols and Plant Phenols

2014 ◽  
Vol 62 (46) ◽  
pp. 11279-11288 ◽  
Author(s):  
Sisse Jongberg ◽  
Marianne N. Lund ◽  
Leif H. Skibsted ◽  
Michael J. Davies
Keyword(s):  
Plant Phenols ◽  
Protein Thiols ◽  
Competitive Reduction

COMPETITIVE REDUCTION OF FERRIHYDRITE AND NONTRONITE AND IMPLICATIONS FOR LACUSTRINE SEDIMENTS

2019 ◽  
Author(s):  
David M. Davis ◽  
◽  
Joshua Malidzo Chidzugwe ◽  
Daniel M. Deocampo
Keyword(s):  
Lacustrine Sediments ◽  
Competitive Reduction

scholarly journals Oxidative damage, inflammation, genotoxic effect, and global DNA methylation caused by inhalation of formaldehyde and the purpose of melatonin

2020 ◽  
Vol 9 (6) ◽  
pp. 778-789
Author(s):  
Letícia Bernardini ◽  
Eduardo Barbosa ◽  
Mariele Feiffer Charão ◽  
Gabriela Goethel ◽  
Diana Muller ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Bone Marrow ◽  
Oxidative Damage ◽  
Bronchoalveolar Lavage ◽  
Bone Marrow Cells ◽  
Histological Study ◽  
Global Dna Methylation ◽  
Protective Effects ◽  
Global Methylation ◽  
Protein Thiols

Abstract Formaldehyde (FA) exposure has been proven to increase the risk of asthma and cancer. This study aimed to evaluate for 28 days the FA inhalation effects on oxidative stress, inflammation process, genotoxicity, and global DNA methylation in mice as well as to investigate the potential protective effects of melatonin. For that, analyses were performed on lung, liver and kidney tissues, blood, and bone marrow. Bronchoalveolar lavage was used to measure inflammatory parameters. Lipid peroxidation (TBARS), protein carbonyl (PCO), non-protein thiols (NPSH), catalase activity (CAT), comet assay, micronuclei (MN), and global methylation were determined. The exposure to 5-ppm FA resulted in oxidative damage to the lung, presenting a significant increase in TBARS and NO levels and a decrease in NPSH levels, besides an increase in inflammatory cells recruited for bronchoalveolar lavage. Likewise, in the liver tissue, the exposure to 5-ppm FA increased TBARS and PCO levels and decreased NPSH levels. In addition, FA significantly induced DNA damage, evidenced by the increase of % tail moment and MN frequency. The pretreatment of mice exposed to FA applying melatonin improved inflammatory and oxidative damage in lung and liver tissues and attenuated MN formation in bone marrow cells. The pulmonary histological study reinforced the results observed in biochemical parameters, demonstrating the potential beneficial role of melatonin. Therefore, our results demonstrated that FA exposure with repeated doses might induce oxidative damage, inflammatory, and genotoxic effects, and melatonin minimized the toxic effects caused by FA inhalation in mice.

scholarly journals Competitive Reduction of Pertechnetate (99TcO4−) by Dissimilatory Metal Reducing Bacteria and Biogenic Fe(II)

2011 ◽  
Vol 45 (3) ◽  
pp. 951-957 ◽  
Author(s):  
Andrew E. Plymale ◽  
James K. Fredrickson ◽  
John M. Zachara ◽  
Alice C. Dohnalkova ◽  
Steve M. Heald ◽  
...  
Keyword(s):  
Competitive Reduction ◽  
Reducing Bacteria ◽  
Metal Reducing Bacteria
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