Dietary Supplementation of Chardonnay Grape Seed Flour Reduces Plasma Cholesterol Concentration, Hepatic Steatosis, and Abdominal Fat Content in High-Fat Diet-Induced Obese Hamsters

2014 ◽  
Vol 62 (8) ◽  
pp. 1919-1925 ◽  
Author(s):  
Hyunsook Kim ◽  
Glenn E. Bartley ◽  
Torey Arvik ◽  
Rebecca Lipson ◽  
Seung-Yeol Nah ◽  
...  
Keyword(s):  
Hepatic Steatosis ◽  
High Fat Diet ◽  
Plasma Cholesterol ◽  
Dietary Supplementation ◽  
Grape Seed ◽  
Abdominal Fat ◽  
Cholesterol Concentration ◽  
High Fat ◽  
Plasma Cholesterol Concentration ◽  
Seed Flour

Dietary supplementation of grape seed and skin flour mitigates brain oxidative damage induced by a high-fat diet in rat: Gender dependency

2017 ◽  
Vol 87 ◽  
pp. 519-526 ◽  
Author(s):  
Kamel Charradi ◽  
Mohamed Mahmoudi ◽  
Takwa Bedhiafi ◽  
Safwen Kadri ◽  
Salem Elkahoui ◽  
...  
Keyword(s):  
Oxidative Damage ◽  
High Fat Diet ◽  
Dietary Supplementation ◽  
Grape Seed ◽  
High Fat

scholarly journals Effect of Sleeve Gastrectomy on Proprotein Convertase Subtilisin/Kexin Type 9 (Pcsk9) Content and Lipid Metabolism in the Blood Plasma and Liver of Obese Wistar Rats

Nutrients ◽  
2019 ◽  
Vol 11 (9) ◽  
pp. 2174 ◽  
Author(s):  
Grzegorczyk ◽  
Książek ◽  
Kurek ◽  
Łukaszuk ◽  
Rosołowski ◽  
...  
Keyword(s):  
Sleeve Gastrectomy ◽  
Lipid Metabolism ◽  
High Fat Diet ◽  
Plasma Cholesterol ◽  
Cholesterol Concentration ◽  
Proprotein Convertase ◽  
Plasma Cholesterol Concentration ◽  
Obese Rats ◽  
Established Fact ◽  
First Time

Nowadays, obesity and its complications are heavy burdens to western civilization. Surgical procedures remain one of the available therapies for obesity and obesity-associated diseases treatment. Among them, sleeve gastrectomy is the most common bariatric procedure. Despite the well-established fact that sleeve gastrectomy results in significant weight loss, some of its other divergent effects still need to be established. To fulfill this knowledge gap, we examined whether sleeve gastrectomy affects lipid metabolism in the plasma and liver of obese rats. We demonstrated that chronic high-fat diet feeding led to an increment in the level of Proprotein Convertase Subtilisin/Kexin (PCSK)—a regulator of plasma cholesterol concentration—in the liver, which was decreased after the gastrectomy. Moreover, we noticed significant increases in both plasma and liver contents of free fatty acids, diacylgycerides and triacylglycerides in the obese animals, with their reduction after the bariatric surgery. In conclusion, we revealed, presumably for the first time, that sleeve gastrectomy affects lipid metabolism in the liver of obese rats.

scholarly journals Time course of changes in in vitro lipolysis of intra-abdominal fat depots in relation to high-fat diet-induced hepatic steatosis in rats

2006 ◽  
Vol 96 (2) ◽  
pp. 268-275 ◽  
Author(s):  
Pascal Collin ◽  
Natalie Chapados ◽  
Elise Dufresne ◽  
Pierre Corriveau ◽  
Pascal Imbeault ◽  
...  
Keyword(s):  
Hepatic Steatosis ◽  
High Fat Diet ◽  
Time Course ◽  
Liver Lipid ◽  
Abdominal Fat ◽  
Standard Diet ◽  
High Fat ◽  
Fat Depots ◽  
Fat Accretion

The purpose of the present study was to determine the time course of changes in in vitro lipolysis and in perilipin content (Western blot) in the mesenteric and/or the retroperitoneal fat depots in relation to the development of hepatic steatosis in high-fat diet-fed rats. Female Sprague-Dawley rats were submitted to a high-fat diet (HF diet; 42% as kJ) or a standard diet (SD diet) for 1, 2, 3 or 8 weeks. Fat accretion in the mesenteric and retroperitoneal tissues was higher (P<0·01) in HF diet-fed than in SD diet-fed rats as soon as 1 week after the beginning of the diet. Liver triacylglycerol concentrations were significantly (P<0·01) higher in HF diet-fed than in SD diet-fed rats throughout the experiment, the highest values being reached at week 2 of the diet. Basal and stimulated lipolysis (10−4 to 10−7m-isoproterienol) in the mesenteric and retroperitoneal fat depots was not changed during the first 3 weeks, regardless of the diet. Lipolysis in the mesenteric adipose tissue in the basal and stimulated states was, however, higher (P<0·01) in HF diet-fed than in SD diet-fed rats after 8 weeks of the diets. There were no significant (P>0·05) effects of diet and time on perilipin content of mesenteric tissue. In spite of a rapid fat accretion, the present results do not provide any evidence of a rapid (3 weeks) increase in in vitro lipolysis in intra-abdominal fat depots upon the undertaking of an HF diet at a time where liver lipid infiltration is the most significant.

Açai (Euterpe oleracea Mart.) seed flour prevents obesity-induced hepatic steatosis regulating lipid metabolism by increasing cholesterol excretion in high-fat diet-fed mice

2018 ◽  
Vol 111 ◽  
pp. 408-415 ◽  
Author(s):  
Renata Cristina da Silva ◽  
Aline Batista ◽  
Danielly C. Ferraz da Costa ◽  
Nathalia Moura-Nunes ◽  
Josely Correa Koury ◽  
...  
Keyword(s):  
Lipid Metabolism ◽  
Hepatic Steatosis ◽  
High Fat Diet ◽  
Euterpe Oleracea ◽  
High Fat ◽  
Seed Flour ◽  
Cholesterol Excretion ◽  
Euterpe Oleracea Mart

Grape seed flour intake decreases adiposity gain in high-fat-diet induced obese mice by activating thermogenesis

2019 ◽  
Vol 62 ◽  
pp. 103509 ◽  
Author(s):  
Fang Zhou ◽  
Manwen Yin ◽  
Yiwen Liu ◽  
Xue Han ◽  
Jielong Guo ◽  
...  
Keyword(s):  
High Fat Diet ◽  
Grape Seed ◽  
Obese Mice ◽  
High Fat ◽  
Seed Flour

Offspring of high fat diet fed dams develop hepatic steatosis

2014 ◽  
Vol 52 (01) ◽  
Author(s):  
JP Sowa ◽  
L Wingerter ◽  
G Gerken ◽  
M Palmert ◽  
A Canbay ◽  
...  
Keyword(s):  
Hepatic Steatosis ◽  
High Fat Diet ◽  
High Fat

scholarly journals Ablation of Akt2 and AMPKα2 rescues high fat diet-induced obesity and hepatic steatosis through Parkin-mediated mitophagy

2021 ◽  
Author(s):  
Shuyi Wang ◽  
Jun Tao ◽  
Huaguo Chen ◽  
Machender R. Kandadi ◽  
Mingming Sun ◽  
...  
Keyword(s):  
Hepatic Steatosis ◽  
High Fat Diet ◽  
High Fat ◽  
Diet Induced Obesity

Dietary Supplementation with Sea Cucumber Saponins and Exercise Can Significantly Suppress Adipose Accumulation in Mice Fed with High-Fat Diet

2021 ◽  
Vol 20 (3) ◽  
pp. 629-640
Author(s):  
Rong Li ◽  
Jing Meng ◽  
Haohao Shi ◽  
Chengcheng Wang ◽  
Zhaojie Li ◽  
...  
Keyword(s):  
High Fat Diet ◽  
Sea Cucumber ◽  
Dietary Supplementation ◽  
High Fat
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