Proteomic Analysis of Duck Fatty Liver during Post-Mortem Storage Related to the Variability of Fat Loss during Cooking of “Foie Gras”

2013 ◽  
Vol 61 (4) ◽  
pp. 920-930 ◽  
Author(s):  
Laetitia Theron ◽  
Xavier Fernandez ◽  
Nathalie Marty-Gasset ◽  
Christophe Chambon ◽  
Didier Viala ◽  
...  
Keyword(s):  
Fatty Liver ◽  
Proteomic Analysis ◽  
Post Mortem ◽  
Fat Loss ◽  
Foie Gras

scholarly journals Identification by Proteomic Analysis of Early Post-mortem Markers Involved in the Variability in Fat Loss during Cooking of Mule Duck “Foie Gras”

2011 ◽  
Vol 59 (23) ◽  
pp. 12617-12628 ◽  
Author(s):  
Laetitia Theron ◽  
Xavier Fernandez ◽  
Nathalie Marty-Gasset ◽  
Carole Pichereaux ◽  
Michel Rossignol ◽  
...  
Keyword(s):  
Proteomic Analysis ◽  
Post Mortem ◽  
Fat Loss ◽  
Foie Gras ◽  
Mule Duck

scholarly journals Fly Foie Gras: Modeling Fatty Liver in Drosophila

2007 ◽  
Vol 5 (2) ◽  
pp. 83-85 ◽  
Author(s):  
Nathalie Arquier ◽  
Pierre Léopold
Keyword(s):  
Fatty Liver ◽  
Foie Gras

scholarly journals The post mortem diagnosis of fatal hypoglycaemia using the fatty liver and kidney syndrome of chicks as a model

1982 ◽  
Vol 47 (2) ◽  
pp. 235-241 ◽  
Author(s):  
D. W. Bannister ◽  
Iris E. O'Neill ◽  
C. C. Whitehead
Keyword(s):  
Fatty Liver ◽  
Plasma Glucose ◽  
Vitreous Humour ◽  
Hepatic Glycogen ◽  
Time Of Death ◽  
Post Mortem ◽  
Liver And Kidney

1. The concentrations of vitreous humour and plasma glucose were closely correlated in both healthy and fatty liver and kidney syndrome-affected chicks at time of death.2. The values of vitreous humour glucose and lactate decreased rapidly after death, such that they were not reliable indicators of the presence of hypoglycaemia immediately ante mortem.3. Hepatic glycogen was extremely low in fatty liver and kidney syndrome-affected birds, whereas significant quantities remained in healthy birds up to at least 24 hpost mortem.

Current advances in proteomic analysis of (fatty) liver

2012 ◽  
Vol 75 (14) ◽  
pp. 4290-4295 ◽  
Author(s):  
C. Molette ◽  
L. Théron ◽  
N. Marty-Gasset ◽  
X. Fernandez ◽  
H. Rémignon
Keyword(s):  
Fatty Liver ◽  
Proteomic Analysis

scholarly journals Slightly different metabolomic profiles are associated with high or low weights duck foie gras

2021 ◽  
Author(s):  
Herve REMIGNON ◽  
Bara LO ◽  
Nathalie Marty-Gasset ◽  
Helene Manse ◽  
Cecile Canlet ◽  
...  
Keyword(s):  
Fatty Liver ◽  
Lipid Synthesis ◽  
Liver Weight ◽  
Liver Metabolism ◽  
Important Change ◽  
Proton Nuclear Magnetic Resonance ◽  
H Nmr ◽  
Low Weight ◽  
Aerobic Energy Metabolism ◽  
Foie Gras

Understanding the evolution of fatty liver metabolism of ducks is a recurrent issue for researchers and industry. Indeed, the increase in weight during the overfeeding period leads to an important change in the liver metabolism. However, liver weight is highly variable at the end of overfeeding within a batch of animals reared, force-fed and slaughtered in the same way. For this study, we performed a proton nuclear magnetic resonance ( 1 H-NMR) analysis on two classes of fatty liver samples, called low-weight liver (weight between 550 and 599 g) and high-weight liver (weight above 700 g). The aim of this study was to identify the differences in metabolism between two classes of liver weight (low and high). Firstly, the results showed that increased liver weight is associated with higher glucose uptake leading to greater lipid synthesis. Secondly, this increase is probably also due to a decline in the level of export of triglycerides and cholesterol from the liver by maintaining them at high hepatic concentration levels. Finally, the increase in liver weight could lead to a significant decrease in the efficiency of aerobic energy metabolism associated with a significant increase in the level of oxidative stress.

scholarly journals Integrative proteomic and lipidomic analysis of Kaili Sour Soup-mediated attenuation of high-fat diet-induced nonalcoholic fatty liver disease in a rat model

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Shuo Cong ◽  
Zhengchao Li ◽  
Lei Yu ◽  
Yongmei Liu ◽  
Yaxin Hu ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Rat Model ◽  
Proteomic Analysis ◽  
High Fat Diet ◽  
Fatty Liver Disease ◽  
High Fat ◽  
Nonalcoholic Fatty Liver ◽  
Lipidomic Analysis

Abstract Background Nonalcoholic fatty liver disease (NAFLD) is the most prevalent liver disease and is characterized by excessive fat accumulation. Kaili Sour Soup, a food typical of Guizhou Province, is believed to have significant health benefits. Thus, we aimed to identify and assess the impact of Kaili Sour Soup on NAFLD and its underlying mechanism using integrative proteomic and lipidomic analysis. Methods A high-fat diet and male Wistar rats were used to construct a NAFLD rat model. Haematoxylin and eosin (HE) and Oil Red O staining analyses were used to perform the histologic examination. Proteomic analysis was utilized to systematically identify the global protein profile in NAFLD with and without Kaili Sour Soup treatment. Western blot assays were used to verify the expression of proteins screened by proteomic analysis. Lipidomic analysis was performed to screen lipid metabolism in NAFLD with and without Kaili Sour Soup treatment. Results Kaili Sour Soup alleviated high-fat diet (HFD)-induced fatty liver and had a normalizing effect on physiological and biochemical indicators of NAFLD, including body weight, liver weight, liver index, total cholesterol (TC), triglyceride (TG), alanine aminotransferase (ALT), aspartate aminotransferase (AST) and insulin resistance level of homeostasis model assessment (HOMA-IR). Kaili Sour Soup decreased the levels of 13 proteins (Tmem44, Rnaseh2b, Gstm6l, LOC100910877, Rufy4, Slc12a2, Pcif1, P4503A1, Sult1e1, Nop53, AABR07065656.4, AABR07065789.3) that were upregulated by HFD and increased the levels of 3 proteins (Sult1c2, Sult1c2a, Snrnp48) that were downregulated by HFD. Kaili Sour Soup attenuated the HFD-induced increase in acyl carnitine (AcCa) and enhanced the HFD-induced decreases in gangliosides (GM3) and lysophosphatidylserine (LPS) in the NAFLD rat model. Conclusions Altogether, this study revealed that Kaili Sour Soup attenuated HFD-induced fatty liver and systematically identified abnormal proteins and lipids involved in the role of Kaili Sour Soup in a NAFLD rat model.

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