Oolong Tea Theasinensins Attenuate Cyclooxygenase-2 Expression in Lipopolysaccharide (LPS)-Activated Mouse Macrophages: Structure−Activity Relationship and Molecular Mechanisms

De-Xing Hou; Satoko Masuzaki; Shunsuke Tanigawa; Fumio Hashimoto; Jihua Chen; Takayuki Sogo; Makoto Fujii

doi:10.1021/jf103605j

Oolong Tea Theasinensins Attenuate Cyclooxygenase-2 Expression in Lipopolysaccharide (LPS)-Activated Mouse Macrophages: Structure−Activity Relationship and Molecular Mechanisms

Journal of Agricultural and Food Chemistry ◽

10.1021/jf103605j ◽

2010 ◽

Vol 58 (24) ◽

pp. 12735-12743 ◽

Cited By ~ 25

Author(s):

De-Xing Hou ◽

Satoko Masuzaki ◽

Shunsuke Tanigawa ◽

Fumio Hashimoto ◽

Jihua Chen ◽

...

Keyword(s):

Molecular Mechanisms ◽

Structure Activity Relationship ◽

Cyclooxygenase 2 ◽

Activity Relationship ◽

Oolong Tea ◽

Structure Activity ◽

Mouse Macrophages

Download Full-text

Green tea proanthocyanidins inhibit cyclooxygenase-2 expression in LPS-activated mouse macrophages: Molecular mechanisms and structure–activity relationship

Archives of Biochemistry and Biophysics ◽

10.1016/j.abb.2007.01.009 ◽

2007 ◽

Vol 460 (1) ◽

pp. 67-74 ◽

Cited By ~ 59

Author(s):

De-Xing Hou ◽

Satoko Masuzaki ◽

Fumio Hashimoto ◽

Takuhiro Uto ◽

Shunsuke Tanigawa ◽

...

Keyword(s):

Green Tea ◽

Molecular Mechanisms ◽

Structure Activity Relationship ◽

Cyclooxygenase 2 ◽

Activity Relationship ◽

Structure Activity ◽

Mouse Macrophages

Download Full-text

Anthocyanidins inhibit cyclooxygenase-2 expression in LPS-evoked macrophages: Structure–activity relationship and molecular mechanisms involved

Biochemical Pharmacology ◽

10.1016/j.bcp.2005.05.003 ◽

2005 ◽

Vol 70 (3) ◽

pp. 417-425 ◽

Cited By ~ 135

Author(s):

De-Xing Hou ◽

Takashi Yanagita ◽

Takuhiro Uto ◽

Satoko Masuzaki ◽

Makoto Fujii

Keyword(s):

Molecular Mechanisms ◽

Structure Activity Relationship ◽

Cyclooxygenase 2 ◽

Activity Relationship ◽

Structure Activity

Download Full-text

Novel Inhibitors of Cyclooxygenase-2: The Sulfones and Sulfonamides of 1,2-diaryl-4,5-difluorobenzene. Analysis of Quantitative Structure-Activity Relationship

Journal of Enzyme Inhibition ◽

10.3109/14756369809020546 ◽

1998 ◽

Vol 13 (6) ◽

pp. 409-417 ◽

Cited By ~ 9

Author(s):

P. Singh ◽

R. Kumar

Keyword(s):

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Cyclooxygenase 2 ◽

Activity Relationship ◽

Quantitative Structure ◽

Structure Activity

Download Full-text

Quantitative structure–activity relationship analysis of 2,3-diaryl indoles as selective cyclooxygenase-2 inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry ◽

10.1080/14756360500277251 ◽

2005 ◽

Vol 20 (5) ◽

pp. 455-461 ◽

Cited By ~ 7

Author(s):

S. PRASANNA ◽

E. MANIVANNAN ◽

S.C. CHATURVEDI

Keyword(s):

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Cyclooxygenase 2 ◽

Activity Relationship ◽

Quantitative Structure ◽

Relationship Analysis ◽

Structure Activity ◽

Cyclooxygenase 2 Inhibitors

Download Full-text

Structure−Activity Relationship and Molecular Mechanisms of Ethyl 2-Amino-4-(2-ethoxy-2-oxoethyl)-6-phenyl-4H-chromene-3-carboxylate (sHA 14-1) and Its Analogues

Journal of Medicinal Chemistry ◽

10.1021/jm9005059 ◽

2009 ◽

Vol 52 (19) ◽

pp. 5937-5949 ◽

Cited By ~ 53

Author(s):

Sonia G. Das ◽

Jignesh M. Doshi ◽

Defeng Tian ◽

Sadiya N. Addo ◽

Balasubramanian Srinivasan ◽

...

Keyword(s):

Molecular Mechanisms ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Structure Activity

Download Full-text

Synthesis and Structure−Activity Relationship Studies of Urea-Containing Pyrazoles as Dual Inhibitors of Cyclooxygenase-2 and Soluble Epoxide Hydrolase

Journal of Medicinal Chemistry ◽

10.1021/jm2001376 ◽

2011 ◽

Vol 54 (8) ◽

pp. 3037-3050 ◽

Cited By ~ 99

Author(s):

Sung Hee Hwang ◽

Karen M. Wagner ◽

Christophe Morisseau ◽

Jun-Yan Liu ◽

Hua Dong ◽

...

Keyword(s):

Epoxide Hydrolase ◽

Soluble Epoxide Hydrolase ◽

Structure Activity Relationship ◽

Cyclooxygenase 2 ◽

Activity Relationship ◽

Structure Activity ◽

Dual Inhibitors

Download Full-text

Suppression by Flavonoids of Cyclooxygenase-2 Promoter-dependent Transcriptional Activity in Colon Cancer Cells: Structure-Activity Relationship

Japanese Journal of Cancer Research ◽

10.1111/j.1349-7006.2000.tb01000.x ◽

2000 ◽

Vol 91 (7) ◽

pp. 686-691 ◽

Cited By ~ 83

Author(s):

Michihiro Mutoh ◽

Mami Takahashi ◽

Kazunori Fukuda ◽

Hajime Komatsu ◽

Takeji Enya ◽

...

Keyword(s):

Colon Cancer ◽

Cancer Cells ◽

Transcriptional Activity ◽

Structure Activity Relationship ◽

Cyclooxygenase 2 ◽

Activity Relationship ◽

Colon Cancer Cells ◽

Structure Activity

Download Full-text

Inhibition of pro-inflammatory markers in primary bone marrow-derived mouse macrophages by naturally occurring flavonoids: Analysis of the structure–activity relationship

Biochemical Pharmacology ◽

10.1016/j.bcp.2006.07.016 ◽

2006 ◽

Vol 72 (8) ◽

pp. 1010-1021 ◽

Cited By ~ 246

Author(s):

Mònica Comalada ◽

Isabel Ballester ◽

Elvira Bailón ◽

Saleta Sierra ◽

Jordi Xaus ◽

...

Keyword(s):

Bone Marrow ◽

Inflammatory Markers ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Naturally Occurring ◽

Structure Activity ◽

Mouse Macrophages ◽

Primary Bone ◽

Primary Bone Marrow

Download Full-text

Abstract 2594: 15-Deoxy-Δ12,14-prostaglandin J2induces apoptosis through covalent interaction with STAT3: structure-activity relationship and underlying molecular mechanisms.

10.1158/1538-7445.am2013-2594 ◽

2013 ◽

Author(s):

Su-Jung Kim ◽

Young-Il Hahn ◽

Bu Young Choi ◽

Young-Ger Suh ◽

Hye-Kyung Na ◽

...

Keyword(s):

Molecular Mechanisms ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Covalent Interaction ◽

Structure Activity

Download Full-text

Novel acid-type cyclooxygenase-2 inhibitors: Design, synthesis, and structure–activity relationship for anti-inflammatory drug

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2012.01.053 ◽

2012 ◽

Vol 50 ◽

pp. 179-195 ◽

Cited By ~ 25

Author(s):

Shigeo Hayashi ◽

Naomi Ueno ◽

Akio Murase ◽

Yoko Nakagawa ◽

Junji Takada

Keyword(s):

Structure Activity Relationship ◽

Cyclooxygenase 2 ◽

Activity Relationship ◽

Design Synthesis ◽

Inflammatory Drug ◽

Structure Activity ◽

Acid Type ◽

Anti Inflammatory ◽

Cyclooxygenase 2 Inhibitors

Download Full-text