Identification of a New Natural Ara h 6 Isoform and of Its Proteolytic Product as Major Allergens in Peanut

2007 ◽  
Vol 55 (23) ◽  
pp. 9663-9669 ◽  
Author(s):  
H. Bernard ◽  
L. Mondoulet ◽  
M. F. Drumare ◽  
E. Paty ◽  
P. Scheinmann ◽  
...  
Keyword(s):  
Ara H 6 ◽  
Major Allergens ◽  
Proteolytic Product

Characterization of Major Allergens of Local Mud Crab (Scylla serrata)

2015 ◽  
Vol 12 (1) ◽  
pp. 1 ◽  
Author(s):  
Rosmilah Misnan ◽  
Nurul Izzah Abdul Rahman ◽  
Zailatul Hani Mohd Yadzir ◽  
Noormalin Abdullah ◽  
Mohd Faizal Bakhtiar ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Arginine Kinase ◽  
Mass Spectrometry Analysis ◽  
Scylla Serrata ◽  
Mud Crab ◽  
Meat Allergy ◽  
Proteomic Approach ◽  
The World ◽  
Major Allergens ◽  
Crab Meat

Crab meat is widely consumed in several countries around the world. However, when consumed, crab meats are frequent cause of allergic reactions throughout the world. Scylla serrata is among the most common mud crab in Malaysia. In a previous study two major allergens of mud crab at 36 and 41 kDa was identified. Thus, the aim of this study is to further identify these major allergens by a proteomic approach. Protein extract was prepared and resolved by 2-dimensional electrophoresis (2-DE). Immunoblotting was then performed using reactive sera from patients with crab allergy. Major allergenic spots were then excised from the 2-DE gel and analysed by mass spectrometry. The 2-DE profile of the extract revealed approximately >100 protein spots between pH of 4.00 to 8.00. Mass spectrometry analysis has identified the 36 and 41 kDa proteins as tropomyosin and arginine kinase, respectively. Our findings indicated that tropomyosin and arginine kinase play a major role in allergic reaction to mud crab meat among local patients with crab meat allergy, and should be included in diagnostics and therapeutic strategies of this allergy.

scholarly journals cDNA cloning and heterologous expression of the major allergens from peach and apple belonging to the lipid-transfer protein family

2002 ◽  
Vol 32 (9) ◽  
pp. 1387-1387 ◽  
Author(s):  
A. Diaz-Perales ◽  
G. Garcia-Casado ◽  
R. Sanchez-Monge ◽  
F. J. Garcia-Selles ◽  
D. Barber ◽  
...  
Keyword(s):  
Heterologous Expression ◽  
Cdna Cloning ◽  
Lipid Transfer Protein ◽  
Protein Family ◽  
Lipid Transfer ◽  
Transfer Protein ◽  
Major Allergens

Thl/Th2 response profiles to the major allergens Cry j 1 and Cry j 2 of Japanese cedar pollen

Allergy ◽  
1996 ◽  
Vol 51 (10) ◽  
pp. 732-740 ◽  
Author(s):  
K. Sugimura ◽  
S. Hashiguchi ◽  
Y. Takahashi ◽  
K. Hino ◽  
Y. Taniguchi ◽  
...  
Keyword(s):  
Japanese Cedar ◽  
Th2 Response ◽  
Response Profiles ◽  
Japanese Cedar Pollen ◽  
Major Allergens ◽  
Cedar Pollen ◽  
Cry J 2

Effect of Lactiplantibacillus plantarum HM-22 on immunoregulation and intestinal microbiota in an α –lactalbumin-induced allergic mouse

2021 ◽  
Author(s):  
Shujuan Jiang ◽  
Yaqi Hou ◽  
Lingying Meng ◽  
Xueli Pu ◽  
Xuemei Zhu ◽  
...  
Keyword(s):  
Intestinal Microbiota ◽  
Milk Protein ◽  
Bovine Milk ◽  
Major Allergens ◽  
Allergic Mouse

Milk protein is one of the eight major allergens, and α–lactalbumin (α-LA) is one of the major allergens of bovine milk protein. Our previous studies found that Lactiplantibacillus plantarum HM-22...

P033 SURFACE EXPRESSION OF MAJOR ALLERGENS ON PLANT-MADE BIOPARTICLES COMBINES HYPO-ALLERGENICITY WITH POTENT IMMUNE ACTIVATION

2021 ◽  
Vol 127 (5) ◽  
pp. S26
Author(s):  
S. Busold ◽  
L. Aglas ◽  
V. Gomord ◽  
V. Stordeur ◽  
L. Vézina ◽  
...  
Keyword(s):  
Immune Activation ◽  
Surface Expression ◽  
Major Allergens

scholarly journals Engineering of structural variants of the major peanut allergens Ara h 2 and Ara h 6 for allergen-specific immunotherapy

2019 ◽  
Vol 143 (3) ◽  
pp. 1226-1229.e10 ◽  
Author(s):  
Merima Bublin ◽  
Maria Kostadinova ◽  
Christian Radauer ◽  
Eva-Maria Varga ◽  
Christine Hafner ◽  
...  
Keyword(s):  
Specific Immunotherapy ◽  
Structural Variants ◽  
Allergen Specific Immunotherapy ◽  
Ara H 2 ◽  
Peanut Allergens ◽  
Ara H 6

IgE responses to Dermatophagoides pteronyssinus native major allergens Der p 1 and Der p 2 during long-term specific immunotherapy

Allergy ◽  
1997 ◽  
Vol 52 (11) ◽  
pp. 1115-1119 ◽  
Author(s):  
F. Mastrandrea ◽  
G. Serio ◽  
A. Minardi ◽  
G. Coradduzza ◽  
N. Rossi ◽  
...  
Keyword(s):  
Specific Immunotherapy ◽  
Dermatophagoides Pteronyssinus ◽  
Der P 1 ◽  
Major Allergens ◽  
Der P 2
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