Effect of Lactiplantibacillus plantarum HM-22 on immunoregulation and intestinal microbiota in an α –lactalbumin-induced allergic mouse

2021 ◽  
Author(s):  
Shujuan Jiang ◽  
Yaqi Hou ◽  
Lingying Meng ◽  
Xueli Pu ◽  
Xuemei Zhu ◽  
...  
Keyword(s):  
Intestinal Microbiota ◽  
Milk Protein ◽  
Bovine Milk ◽  
Major Allergens ◽  
Allergic Mouse

Milk protein is one of the eight major allergens, and α–lactalbumin (α-LA) is one of the major allergens of bovine milk protein. Our previous studies found that Lactiplantibacillus plantarum HM-22...

A Retrospective Analysis of the Effects of an Exclusively Human Milk Protein Diet on Neonatal Feeding Tolerance

2020 ◽  
Author(s):  
Jessica Wickland ◽  
Christine Wade ◽  
Becky Micetic ◽  
Keith Meredith ◽  
Gregory Martin
Keyword(s):  
Birth Weight ◽  
Human Milk ◽  
Milk Protein ◽  
Very Low Birth Weight ◽  
Bovine Milk ◽  
Milk Diet ◽  
Vlbw Infants ◽  
Key Points ◽  
Human Milk Protein ◽  
Feeding Tolerance

Objective This study was aimed to evaluate the effect of human milk protein fortifier (HMPF) versus bovine milk protein fortifier (BMPF) on feeding tolerance defined as the time to reach full feeds and necrotizing enterocolitis (NEC) in premature very low birth weight (VLBW) infants. Study Design A retrospective review using the BabySteps Database included 493 infants born ≤33 weeks of gestational age and ≤1,250 g (g) birth weight. A total of 218 infants fed a human milk diet (HMD) with BMPF were compared with 275 infants fed an HMD with HMPF. Results Full feeds were reached significantly sooner in the HMPF group (median: 14 vs. 16 days, p = 0.04). Weight at full feeds was significantly lower in the HMPF group (1,060 vs. 1110 g, p = 0.03). Conclusion Using HMPF to provide an exclusively HMD allowed VLBW infants to achieve full feeds sooner, but did not affect rate of NEC compared with using a BMPF with an HMD. Key Points

scholarly journals A2 Bovine Milk and Caprine Milk as a Means of Remedy for Milk Protein Allergy

Dairy ◽  
2021 ◽  
Vol 2 (2) ◽  
pp. 191-201
Author(s):  
Young W. Park ◽  
George F. W. Haenlein
Keyword(s):  
Milk Protein ◽  
Bovine Milk ◽  
Goat Milk ◽  
Food Sources ◽  
Cow Milk ◽  
Cow’S Milk ◽  
Dairy Goat ◽  
Cow's Milk ◽  
Caprine Milk ◽  
Low Levels

A new type of cow’s milk, called A2 milk, has appeared in the dairy aisles of supermarkets in recent years. Cows’ milk generally contains two major types of beta-casein as A1 and A2 types, although there are 13 genetic variants of β-casein: A1, A2, A3, A4, B, C, D, E, F, H1, H2, I and G. Studies have shown that A1 β-casein may be harmful, and A2 β-casein is a safer choice for human health especially in infant nutrition and health. The A2 cow milk is reportedly easier to digest and better absorb than A1 or other types of milk. The structure of A2 cow’s milk protein is more comparable to human breast milk, as well as milk from goats, sheep and buffalo. Digestion of A1 type milk produces a peptide called β-casomorphin-7 (BCM-7), which is implicated with adverse gastrointestinal effects on milk consumption. In addition, bovine milk contains predominantly αs1-casein and low levels or even absent in αs2-casein, whereby caprine milk has been recommended as an ideal substitute for patients suffering from allergies against cow milk protein or other food sources. Since goat milk contains relatively low levels of αs1-casein or negligible its content, and αs2-casein levels are high in the milk of most dairy goat breeds, it is logical to assume that children with a high milk sensitivity to αs1-casein should tolerate goat milk well. Cow milk protein allergy (CMPA) is considered a common milk digestive and metabolic disorder or allergic disease with various levels of prevalence from 2.5% in children during the first 3 years of life to 12–30% in infants less than 3 months old, and it can go up to even as high as 20% in some countries. CMPA is an IgE-mediated allergy where the body starts to produce IgE antibodies against certain protein (allergens) such as A1 milk and αs1-casein in bovine milk. Studies have shown that ingestion of β-casein A1 milk can cause ischemic heart disease, type-1 diabetes, arteriosclerosis, sudden infant death syndrome, autism, schizophrenia, etc. The knowledge of bovine A2 milk and caprine αs2-casein has been utilized to rescue CMPA patients and other potential disease problems. This knowledge has been genetically applied to milk production in cows or goats or even whole herds of the two species. This practice has happened in California and Ohio, as well as in New Zealand, where this A2 cow milk has been now advanced commercially. In the USA, there have been even promotions of bulls, whose daughters have been tested homozygous for the A2 β-casein protein.

scholarly journals Insulin autoantibodies with high affinity to the bovine milk protein alpha casein

2011 ◽  
Vol 164 (1) ◽  
pp. 42-49 ◽  
Author(s):  
K. Adler ◽  
D. B. Mueller ◽  
P. Achenbach ◽  
S. Krause ◽  
A.-K. Heninger ◽  
...  
Keyword(s):  
Milk Protein ◽  
Bovine Milk ◽  
Insulin Autoantibodies ◽  
High Affinity

Hormone-dependent milk protein gene expression in bovine mammary explants from biopsies at different stages of pregnancy

2004 ◽  
Vol 71 (2) ◽  
pp. 135-140 ◽  
Author(s):  
Paul A Sheehy ◽  
James J Della-Vedova ◽  
Kevin R Nicholas ◽  
Peter C Wynn
Keyword(s):  
Gene Expression ◽  
Milk Protein ◽  
Protein Gene ◽  
Bovine Milk ◽  
Mammary Tissue ◽  
Endocrine Regulation ◽  
Surgical Biopsy ◽  
Milk Protein Gene ◽  
Milk Protein Gene Expression

A method for the collection of mammary biopsies developed previously was refined and used to study the endocrine regulation of bovine milk protein gene expression. Our surgical biopsy method used real-time ultrasound imaging and epidural analgesia to enable recovery of a sufficient quantity of mammary tissue from late-pregnant dairy cows for explant culture in vitro. The time of biopsy was critical for prolactin-dependent induction of milk protein gene expression in mammary explants, as only mammary tissue from cows nearing 30 d prepartum was hormone-responsive. This suggests that during the later stages of pregnancy a change in the responsiveness of milk protein gene expression to endocrine stimuli occurred in preparation for lactation. This may relate to the diminution of a putative population of undifferentiated cells that were still responsive to prolactin. Alternatively, the metabolic activity of the tissue had increased to the level whereby the response of the tissue was no longer assessable using this model in vitro.

Bovine Milk Protein-Induced Intestinal Malabsorption of Lactose and Fat in Infants

1968 ◽  
Vol 54 (1) ◽  
pp. 27-34 ◽  
Author(s):  
Hsi-Yen Liu ◽  
M.U. Tsao ◽  
B. Moore ◽  
Z. Giday
Keyword(s):  
Milk Protein ◽  
Bovine Milk ◽  
Intestinal Malabsorption

scholarly journals Structural and functional characteristics of bovine milk protein glycosylation

Glycobiology ◽  
2014 ◽  
Vol 24 (3) ◽  
pp. 220-236 ◽  
Author(s):  
N. O'Riordan ◽  
M. Kane ◽  
L. Joshi ◽  
R. M. Hickey
Keyword(s):  
Milk Protein ◽  
Bovine Milk ◽  
Protein Glycosylation ◽  
Functional Characteristics

Efficacy of mouthrinses with bovine milk and milk protein isolates to accumulate casein in the in situ pellicle

2020 ◽  
Vol 24 (11) ◽  
pp. 3871-3880
Author(s):  
A. Kensche ◽  
S. Pötschke ◽  
C. Hannig ◽  
A. Dürasch ◽  
T. Henle ◽  
...  
Keyword(s):  
Milk Protein ◽  
Bovine Milk ◽  
Protein Isolates
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