Flavonoid glycosides of Spartan apple peel

1987 ◽  
Vol 35 (4) ◽  
pp. 529-531 ◽  
Author(s):  
Arthur J. Dick ◽  
Peter R. Redden ◽  
Alphonse C. DeMarco ◽  
Perry D. Lidster ◽  
T. Bruce Grindley
Keyword(s):  
Flavonoid Glycosides ◽  
Apple Peel

Biologically active flavonoid glycosides from Horwoodia dicksoniae Turrill

Planta Medica ◽  
2011 ◽  
Vol 77 (12) ◽  
Author(s):  
GA Fawzy ◽  
AM Al Taweel ◽  
NA Abdelbaky ◽  
MS Marzouk
Keyword(s):  
Biologically Active ◽  
Flavonoid Glycosides

Flavonoid-glycosides from Rumex aquaticus with neuroprotective activity

Planta Medica ◽  
2014 ◽  
Vol 80 (16) ◽  
Author(s):  
O Orban-Gyapai ◽  
A Raghavan ◽  
A Vasas ◽  
P Forgo ◽  
ZA Shah ◽  
...  
Keyword(s):  
Neuroprotective Activity ◽  
Flavonoid Glycosides

Oral Allergy Syndrome (OAS) from Allergen Considered to be Contained in Apple Peel.

2003 ◽  
Vol 65 (1) ◽  
pp. 3-5
Author(s):  
Yoshinori SASAKI ◽  
Yutaka KIMURA ◽  
Takahiko TSUNODA ◽  
Eiichi TOKUNAGA ◽  
Hiroyuki OHSUNA ◽  
...  
Keyword(s):  
Oral Allergy Syndrome ◽  
Apple Peel

Selective hydrolysis of flavonoid glycosides by Curvularia lunata

2014 ◽  
Vol 11 (6) ◽  
pp. 684-689 ◽  
Author(s):  
Jing-Yuan LIU ◽  
He-Shui YU ◽  
Bing FENG ◽  
Li-Ping KANG ◽  
Xu PANG ◽  
...  
Keyword(s):  
Flavonoid Glycosides ◽  
Curvularia Lunata ◽  
Selective Hydrolysis ◽  
Hydrolysis Of

scholarly journals Flavonoid Glycosides with a Triazole Moiety for Marine Antifouling Applications: Synthesis and Biological Activity Evaluation

Marine Drugs ◽  
2020 ◽  
Vol 19 (1) ◽  
pp. 5
Author(s):  
Daniela Pereira ◽  
Catarina Gonçalves ◽  
Beatriz T. Martins ◽  
Andreia Palmeira ◽  
Vitor Vasconcelos ◽  
...  
Keyword(s):  
Qsar Model ◽  
Quantitative Structure Activity Relationship ◽  
Artemia Salina ◽  
Flavonoid Glycosides ◽  
Antifouling Activity ◽  
Antifouling Coatings ◽  
Marine Industry ◽  
Low Toxicity ◽  
Polymethoxylated Flavones ◽  
First Time

Over the last decades, antifouling coatings containing biocidal compounds as active ingredients were used to prevent biofouling, and eco-friendly alternatives are needed. Previous research from our group showed that polymethoxylated chalcones and glycosylated flavones obtained by synthesis displayed antifouling activity with low toxicity. In this work, ten new polymethoxylated flavones and chalcones were synthesized for the first time, including eight with a triazole moiety. Eight known flavones and chalcones were also synthesized and tested in order to construct a quantitative structure-activity relationship (QSAR) model for these compounds. Three different antifouling profiles were found: three compounds (1b, 11a and 11b) exhibited anti-settlement activity against a macrofouling species (Mytilus galloprovincialis), two compounds (6a and 6b) exhibited inhibitory activity against the biofilm-forming marine bacteria Roseobacter litoralis and one compound (7b) exhibited activity against both mussel larvae and microalgae Navicula sp. Hydrogen bonding acceptor ability of the molecule was the most significant descriptor contributing positively to the mussel larvae anti-settlement activity and, in fact, the triazolyl glycosylated chalcone 7b was the most potent compound against this species. The most promising compounds were not toxic to Artemia salina, highlighting the importance of pursuing the development of new synthetic antifouling agents as an ecofriendly and sustainable alternative for the marine industry.

scholarly journals Chemical compositions, antimicrobial effects, and cytotoxicity of Asia minor wormwood (Artemisia splendens Willd.) growing in Iran

BMC Chemistry ◽  
2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Fariba Heshmati Afshar ◽  
Masumeh Zadehkamand ◽  
Zahra Rezaei ◽  
Abbas Delazar ◽  
Vahideh Tarhriz ◽  
...  
Keyword(s):  
Cell Line ◽  
Proliferative Activity ◽  
Methanolic Extract ◽  
Biologically Active ◽  
Flavonoid Glycosides ◽  
Control Group ◽  
Chemical Compositions ◽  
Preparative Hplc ◽  
Cytotoxicity Activity ◽  
Methanolic Extracts

Abstract Background Artemisia splendens from the Asteraceae family is a new source of biologically active compounds. The current study investigated to evaluate antimicrobial and cytotoxicity activity of methanolic extracts and their fractions obtained from aerial parts by agar disk diffusion and MTT methods, respectively. The active fractions were subjected to preparative HPLC for isolating the pure compounds, which were structurally elucidated, by 1H and 13C NMR. Results The results showed that the methanolic extract and its 60% SPE fraction have the anti-proliferative activity on A549 cell line in comparison with the control group. Meanwhile, the methanolic extract and its 40% SPE fraction can inhibit the growth of Gram-positive strains as anti-microbial activity. The 60% SPE fraction also illustrated anti-proliferative activity on the HT-29 cell line compared to the control group. Chromatographic separations via preparative HPLC yielded 5 flavonoids and three flavonoid glycosides. Conclusion Based on the results it can be concluded that A. splendens as a potential source of cytotoxic and antimicrobial compounds can be used in pharmaceutics.

Dynamic changes of antioxidants and fermentative metabolites in apple peel in relation to storage, controlled atmosphere, and initial low oxygen stress

2021 ◽  
Vol 288 ◽  
pp. 110312
Author(s):  
Marina Buccheri ◽  
Valentina Picchi ◽  
Maurizio Grassi ◽  
Davide Gandin ◽  
Giulia Bianchi ◽  
...  
Keyword(s):  
Controlled Atmosphere ◽  
Low Oxygen ◽  
Dynamic Changes ◽  
Oxygen Stress ◽  
Apple Peel

scholarly journals Anti-MRSA Constituents from Ruta chalepensis (Rutaceae) Grown in Iraq, and In Silico Studies on Two of Most Active Compounds, Chalepensin and 6-Hydroxy-rutin 3′,7-Dimethyl ether

Molecules ◽  
2021 ◽  
Vol 26 (4) ◽  
pp. 1114 ◽  
Author(s):  
Shaymaa Al-Majmaie ◽  
Lutfun Nahar ◽  
M. Mukhlesur Rahman ◽  
Sushmita Nath ◽  
Priyanka Saha ◽  
...  
Keyword(s):  
Dimethyl Ether ◽  
In Silico ◽  
Efflux Pump ◽  
Perennial Herb ◽  
Flavonoid Glycosides ◽  
Cinnamic Acid Derivative ◽  
Active Compounds ◽  
Ruta Chalepensis ◽  
In Silico Studies ◽  
Mrsa Strains

Ruta chalepensis L. (Rutaceae), a perennial herb with wild and cultivated habitats, is well known for its traditional uses as an anti-inflammatory, analgesic, antipyretic agent, and in the treatment of rheumatism, nerve diseases, neuralgia, dropsy, convulsions and mental disorders. The antimicrobial activities of the crude extracts from the fruits, leaves, stem and roots of R. chalepensis were initially evaluated against two Gram-positive and two Gram-negative bacterial strains and a strain of the fungus Candida albicans. Phytochemical investigation afforded 19 compounds, including alkaloids, coumarins, flavonoid glycosides, a cinnamic acid derivative and a long-chain alkane. These compounds were tested against a panel of methicillin-resistant Staphylococcus aureus (MRSA) strains, i.e., ATCC 25923, SA-1199B, XU212, MRSA-274819 and EMRSA-15. The MIC values of the active compounds, chalepin (9), chalepensin (10), rutamarin (11), rutin 3′-methyl ether (14), rutin 7,4′-dimethyl ether (15), 6-hydroxy-rutin 3′,7-dimethyl ether (16) and arborinine (18) were in the range of 32–128 µg/mL against the tested MRSA strains. Compounds 10 and 16 were the most active compounds from R. chalepensis, and were active against four out of six tested MRSA strains, and in silico studies were performed on these compounds. The anti-MRSA activity of compound 16 was comparable to that of the positive control norfloxacin (MICs 32 vs 16 μg/mL, respectively) against the MRSA strain XU212, which is a Kuwaiti hospital isolate that possesses the TetK tetracycline efflux pump. This is the first report on the anti-MRSA property of compounds isolated from R. chalepensis and relevant in silico studies on the most active compounds.

scholarly journals Flavonoid Glycosides in Brassica Species Respond to UV-B Depending on Exposure Time and Adaptation Time

Molecules ◽  
2021 ◽  
Vol 26 (2) ◽  
pp. 494
Author(s):  
Susanne Neugart ◽  
Christiane Bumke-Vogt
Keyword(s):  
Brassica Species ◽  
Flavonoid Glycoside ◽  
Ultraviolet B ◽  
Flavonoid Glycosides ◽  
Production Cycle ◽  
Short Term ◽  
Greenhouse Production ◽  
Adaptation Time ◽  
Quercetin Glycosides ◽  
Kaempferol Glycosides

Recently, there have been efforts to use ultraviolet-B radiation (UV-B) as a biotechnological tool in greenhouses. Leafy Brassica species are mainly considered for their ability to synthesize glucosinolates and are valued as baby salads. They also have a remarkable concentration of chemically diverse flavonoid glycosides. In this study, the effect of short-term UV-B radiation at the end of the production cycle was investigated without affecting plant growth. The aim was to verify which exposure and adaptation time was suitable and needs to be further investigated to use UV as a biotechnological tool in greenhouse production of Brassica species. It is possible to modify the flavonoid glycoside profile of leafy Brassica species by increasing compounds that appear to have potentially high antioxidant activity. Exemplarily, the present experiment shows that kaempferol glycosides may be preferred over quercetin glycosides in response to UV-B in Brassica rapa ssp. chinensis, for example, whereas other species appear to prefer quercetin glycosides over kaempferol glycosides, such as Brassica oleracea var. sabellica or Brassica carinata. However, the response to short-term UV-B treatment is species-specific and conclusions on exposure and adaptation time cannot be unified but must be drawn separately for each species.

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