Orthogonal Array Design for the Optimization of Supercritical Carbon Dioxide Extraction of Different Metals from a Solid Matrix with Cyanex 301 as a Ligand

2004 ◽  
Vol 49 (6) ◽  
pp. 1530-1534 ◽  
Author(s):  
Seied Mahdi Pourmortazavi ◽  
Seiedeh Somayyeh Hajimirsadeghi ◽  
Iraj Kohsari ◽  
Seied Ghorban Hosseini
Keyword(s):  
Carbon Dioxide ◽  
Supercritical Carbon Dioxide ◽  
Orthogonal Array ◽  
Solid Matrix ◽  
Supercritical Carbon Dioxide Extraction ◽  
Orthogonal Array Design ◽  
Array Design ◽  
Carbon Dioxide Extraction ◽  
Cyanex 301 ◽  
Supercritical Carbon

scholarly journals Supercritical Fluid Extraction of Pyrrolidine Alkaloid from Leaves of Piper amalago L.

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
V. S. Carrara ◽  
L. C. Filho ◽  
V. A. S. Garcia ◽  
V. S. Faiões ◽  
E. F. Cunha-Júnior ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Supercritical Fluid Extraction ◽  
Supercritical Fluid ◽  
Orthogonal Array ◽  
Design Matrix ◽  
Supercritical Carbon Dioxide Extraction ◽  
Orthogonal Array Design ◽  
Fluid Extraction ◽  
Array Design ◽  
Carbon Dioxide Extraction

Supercritical fluid extraction was used to extract the alkaloid N-[7-(3′,4′-methylenedioxyphenyl)-2(Z),4(Z)-heptadienoyl]pyrrolidine from leaves of Piper amalago L. A three-level orthogonal array design matrix, OAD OA9(34), was used for optimization of the parameters of supercritical extraction of the alkaloid, employing supercritical carbon dioxide: extraction time (20, 40, and 60 min), temperature (40, 50, and 60°C), pressure (150, 200, and 250 bar), and the use of cosolvents (ethanol, methanol, and propyleneglycol). All parameters had significant effect on the alkaloid yield. The alkaloid yield after 60 min of extraction without cosolvents at 9 different conditions (32) in terms of temperature (40, 50, and 60°C) and pressure (150, 200, and 250 bar) was also evaluated. The optimal yield (≈3.8 mg g−1) was obtained with supercritical CO2 + methanol (5% v : v) at 40°C and 200 bar for 60 min of extraction.

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