Catalytic Asymmetric Direct-Type 1,4-Addition Reactions of Simple Amides

2015 ◽  
Vol 137 (13) ◽  
pp. 4336-4339 ◽  
Author(s):  
Hirotsugu Suzuki ◽  
Io Sato ◽  
Yasuhiro Yamashita ◽  
Shu̅ Kobayashi
Keyword(s):  
Addition Reactions ◽  
Catalytic Asymmetric

A Strategy for Synthesizing Axially Chiral Naphthyl‐Indoles: Catalytic Asymmetric Addition Reactions of Racemic Substrates

2019 ◽  
Vol 131 (42) ◽  
pp. 15248-15254 ◽  
Author(s):  
Fei Jiang ◽  
Ke‐Wei Chen ◽  
Ping Wu ◽  
Yu‐Chen Zhang ◽  
Yinchun Jiao ◽  
...  
Keyword(s):  
Addition Reactions ◽  
Asymmetric Addition ◽  
Axially Chiral ◽  
Catalytic Asymmetric

Catalytic asymmetric addition reactions leading to carbon-carbon bond formation: Phenyl and alkenyl transfer to aldehydes and alkynylation of α-imino esters

2006 ◽  
Vol 78 (2) ◽  
pp. 267-274 ◽  
Author(s):  
Jian-Xin Ji ◽  
Jing Wu ◽  
Lijin Xu ◽  
Chiu-Wing Yip ◽  
Kim Hung Lam ◽  
...  
Keyword(s):  
Bond Formation ◽  
Optically Active ◽  
Amino Acid Derivatives ◽  
Addition Reactions ◽  
Terminal Alkynes ◽  
Reaction Conditions ◽  
Carbon Carbon Bond ◽  
Catalytic Asymmetric ◽  
High Yields ◽  
Imino Esters

Optically active tertiary aminonaphthol ligands were obtained by a new, convenient procedure and were found to catalyze the enantioselective alkenyl and phenyl transfer to aldehydes in high yields and excellent enantiomeric excesses (ee's). The catalytic asymmetric introduction of alkynyl functionality to α-amino acid derivatives was realized by the direct addition of terminal alkynes to α-imino ester in the presence of chiral copper(I) complex under mild reaction conditions.

Catalytic Asymmetric 1,4-Addition Reactions Using α,β-UnsaturatedN-Acylpyrroles as Highly Reactive Monodentate α,β-Unsaturated Ester Surrogates

2004 ◽  
Vol 126 (24) ◽  
pp. 7559-7570 ◽  
Author(s):  
Shigeki Matsunaga ◽  
Tomofumi Kinoshita ◽  
Shigemitsu Okada ◽  
Shinji Harada ◽  
Masakatsu Shibasaki
Keyword(s):  
Unsaturated Ester ◽  
Addition Reactions ◽  
Catalytic Asymmetric

ChemInform Abstract: Catalytic Asymmetric 1,4-Addition Reactions of Simple Alkylnitriles.

ChemInform ◽  
2016 ◽  
Vol 47 (6) ◽  
pp. no-no
Author(s):  
Yasuhiro Yamashita ◽  
Io Sato ◽  
Hirotsugu Suzuki ◽  
Shu Kobayashi
Keyword(s):  
Addition Reactions ◽  
Catalytic Asymmetric

Catalytic asymmetric direct-type 1,4-addition reactions of simple esters

2016 ◽  
Vol 3 (10) ◽  
pp. 1241-1245 ◽  
Author(s):  
Io Sato ◽  
Hirotsugu Suzuki ◽  
Yasuhiro Yamashita ◽  
Shū Kobayashi
Keyword(s):  
Addition Reactions ◽  
Catalytic Asymmetric

Catalytic asymmetric 1,4-addition reactions of simple esters have been developed. The desired reactions proceeded smoothly with high enantioselectivities.

Catalytic Asymmetric 1,4-Addition Reactions of Simple Alkylnitriles

2015 ◽  
Vol 10 (10) ◽  
pp. 2143-2146 ◽  
Author(s):  
Yasuhiro Yamashita ◽  
Io Sato ◽  
Hirotsugu Suzuki ◽  
Shū Kobayashi
Keyword(s):  
Addition Reactions ◽  
Catalytic Asymmetric

Catalytic asymmetric aldol addition reactions of 3-fluoro-indolinone derived enolates

2017 ◽  
Vol 15 (2) ◽  
pp. 311-315 ◽  
Author(s):  
Lijun Zhang ◽  
Wenzhong Zhang ◽  
Haibo Mei ◽  
Jianlin Han ◽  
Vadim A. Soloshonok ◽  
...  
Keyword(s):  
Aldol Reactions ◽  
Addition Reactions ◽  
Asymmetric Aldol ◽  
Wide Range ◽  
Stereogenic Centers ◽  
New Type ◽  
Catalytic Asymmetric ◽  
Aldol Addition ◽  
Quaternary Stereogenic Centers

Cu(i)/bisoxazoline ligand catalyzed asymmetric aldol reactions of fluoro-indolinone derived new type tertiary enolates have been developed. This process allows the preparation of a wide range of α-fluoro-β-aryl/hetaryl/alkyl-β-hydroxy-indolin-2-one products containing C–F quaternary stereogenic centers.

scholarly journals Cp*CoIII-Catalyzed C–H Functionalization and Asymmetric Reactions Using External Chiral Sources

Synlett ◽  
2019 ◽  
Vol 30 (12) ◽  
pp. 1384-1400 ◽  
Author(s):  
Tatsuhiko Yoshino ◽  
Shigeki Matsunaga
Keyword(s):  
Carboxylic Acids ◽  
Asymmetric Reactions ◽  
Addition Reactions ◽  
Double Bonds ◽  
Cyclization Reactions ◽  
Catalytic Asymmetric ◽  
Allyl Alcohols

This account describes Cp*CoIII-catalyzed C–H functionalization reactions developed in our group between 2013 and 2018. Cp*CoIII catalysts not only serve as inexpensive alternatives to Cp*RhIII catalysts but also exhibit unique reactivity and selectivity in several transformations. In the latter part of this review, we introduce catalytic asymmetric C–H functionalization reactions using achiral RhIII or CoIII catalysts with chiral disulfonates or carboxylic acids as external chiral sources.1 Introduction and Overview2 Cp*CoIII-Catalyzed C–H Functionalization Reactions2.1 C–H Addition Reactions to Polar Double Bonds2.2 Cp*Co(CO)I2 and [Cp*CoI2]2 Precursors for the C2-selective C–H Amidation of Indoles2.3 C–H Functionalization of Carbamoyl-Protected Indoles Using Alkynes2.4 C–H Allylation Using Allyl Alcohols2.5 Cyclization Reactions of O-Acyloximes and Alkynes2.6 Other Miscellaneous Reactions3 Enantioselective C–H Functionalization Reactions by Hybrid Catalysis3.1 Cp*RhIII/Chiral Disulfonate Catalysts for the Enantioselective C–H Addition to Enones3.2 Enantioselective C–H Cleavage Using Chiral Carboxylic Acids4 Summary and Perspective

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