Conformationally Constrained Peptide Mimetics:  The Use of a Small Lactam Ring as an HIV-1 Antigen Constraint

1997 ◽  
Vol 119 (50) ◽  
pp. 12394-12395 ◽  
Author(s):  
Robert D. Long ◽  
Kevin D. Moeller
Keyword(s):  
Peptide Mimetics ◽  
Conformationally Constrained ◽  
Lactam Ring ◽  
Hiv 1

Conformationally Restricted Peptide Mimetics: The Incorporation of 6,5-Bicyclic Lactam Ring Skeletons into Peptides

1995 ◽  
Vol 60 (25) ◽  
pp. 8155-8170 ◽  
Author(s):  
Wenhao Li ◽  
Cathleen E. Hanau ◽  
Andre dAvignon ◽  
Kevin D. Moeller
Keyword(s):  
Peptide Mimetics ◽  
Conformationally Restricted ◽  
Lactam Ring

Novel conformationally constrained HIV-1 protease inhibitors: rational design, enzyme inhibition, and X-ray structure of an enzyme-inhibtor complex

1994 ◽  
Vol 4 (18) ◽  
pp. 2199-2204 ◽  
Author(s):  
B.Moon Kim ◽  
Joseph P. Vacca ◽  
Paula M.D. Fitzgerald ◽  
Paul L. Darke ◽  
M.Katharine Holloway ◽  
...  
Keyword(s):  
Protease Inhibitors ◽  
Enzyme Inhibition ◽  
Rational Design ◽  
Conformationally Constrained ◽  
X Ray ◽  
Hiv 1

Immunofocusing using conformationally constrained V3 peptide immunogens improves HIV-1 neutralization

Vaccine ◽  
2017 ◽  
Vol 35 (2) ◽  
pp. 222-230 ◽  
Author(s):  
Adi Moseri ◽  
Eshu Sinha ◽  
Henni Zommer ◽  
Boris Arshava ◽  
Fred Naider ◽  
...  
Keyword(s):  
Conformationally Constrained ◽  
Hiv 1

Design of peptide mimetics of HIV-1 gp120 for prevention and therapy of HIV disease

2003 ◽  
Vol 62 (4) ◽  
pp. 158-166 ◽  
Author(s):  
N. Veljkovic ◽  
D.R. Branch ◽  
R. Metlas ◽  
J Prljic ◽  
K. Vlahovicek ◽  
...  
Keyword(s):  
Peptide Mimetics ◽  
Hiv Disease ◽  
Hiv 1 ◽  
Prevention And Therapy

Progress towards new conformationally constrained HIV-1 protease inhibitors

1995 ◽  
Vol 30 (11) ◽  
pp. 891-900 ◽  
Author(s):  
Z Benatalah ◽  
N Trigui ◽  
S Sicsic ◽  
T Tonnaire ◽  
E de Rosny ◽  
...  
Keyword(s):  
Protease Inhibitors ◽  
Conformationally Constrained ◽  
Hiv 1

Design and synthesis of conformationally constrained amino acids as versatile scaffolds and peptide mimetics

Tetrahedron ◽  
1997 ◽  
Vol 53 (38) ◽  
pp. 12789-12854 ◽  
Author(s):  
Stephen Hanessian ◽  
Grant McNaughton-Smith ◽  
Henry-Georges Lombart ◽  
William D. Lubell
Keyword(s):  
Amino Acids ◽  
Peptide Mimetics ◽  
Conformationally Constrained ◽  
Design And Synthesis ◽  
Conformationally Constrained Amino Acids ◽  
Constrained Amino Acids

Examination of HIV-1 protease secondary structure specificity using conformationally constrained inhibitors

1991 ◽  
Vol 34 (12) ◽  
pp. 3395-3399 ◽  
Author(s):  
Michael Kahn ◽  
Hiroshi Nakanishi ◽  
R. Alan Chrusciel ◽  
Dennis Fitzpatrick ◽  
Michael E. Johnson
Keyword(s):  
Secondary Structure ◽  
Conformationally Constrained ◽  
Hiv 1
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