scholarly journals Coibamide A, a Potent Antiproliferative Cyclic Depsipeptide from the Panamanian Marine CyanobacteriumLeptolyngbyasp.

2008 ◽  
Vol 130 (20) ◽  
pp. 6324-6325 ◽  
Author(s):  
Rebecca A. Medina ◽  
Douglas E. Goeger ◽  
Patrice Hills ◽  
Susan L. Mooberry ◽  
Nelson Huang ◽  
...  
Keyword(s):  
Cyclic Depsipeptide ◽  
Coibamide A

scholarly journals Isolation of Heptadepsin, a Novel Bacterial Cyclic Depsipeptide that Inhibits Lipopolysaccharide Activity

2004 ◽  
Vol 11 (8) ◽  
pp. 1059-1070 ◽  
Author(s):  
Osamu Ohno ◽  
Yoko Ikeda ◽  
Ryuichi Sawa ◽  
Masayuki Igarashi ◽  
Naoko Kinoshita ◽  
...  
Keyword(s):  
Cyclic Depsipeptide

scholarly journals Benderamide A, a Cyclic Depsipeptide from a Singapore Collection of Marine Cyanobacterium cf. Lyngbya sp.

Marine Drugs ◽  
2018 ◽  
Vol 16 (11) ◽  
pp. 409 ◽  
Author(s):  
Chi Ding ◽  
Ji Ong ◽  
Hui Goh ◽  
Cynthia Coffill ◽  
Lik Tan
Keyword(s):  
Breast Cancer Cells ◽  
Nuclear Overhauser Effect ◽  
2D Nmr ◽  
Marine Cyanobacterium ◽  
One Dimensional ◽  
Mechanistic Pathway ◽  
Overhauser Effect ◽  
Cyclic Depsipeptide ◽  
Nuclear Overhauser ◽  
Related Compounds

Benderamide A (1), a (S)-2,2-dimethyl-3-hydroxy-7-octynoic acid (S-Dhoya)-containing cyclic depsipeptide that belongs to the kulolide superfamily, was isolated from a Singapore collection of cf. Lyngbya sp. marine cyanobacterium using a bioassay-guided approach. While the planar structure of 1 was elucidated using a combination of 1D and 2D NMR experiments and MS analysis, the absolute configuration was subsequently achieved using the results obtained from Marfey’s analysis, comparative analysis of nuclear overhauser effect spectroscopy (NOESY) with the known compound 3, and one dimensional-nuclear overhauser effect (1D-NOE). Although 1 did not display antiproliferative activity against MCF7 breast cancer cells, the presence of an Ala instead of Gly suggests a possible mechanistic pathway to explain the consequential decrease in cytotoxicity compared to the closely related 2. In addition, results obtained from an LC–MS/MS-based molecular networking algorithm revealed two other closely related compounds encouraging further identification and isolation from the same marine cyanobacterium extract.

ChemInform Abstract: Arthogalin, a Cyclic Depsipeptide from the Lichen Arthothelium galapagoense.

ChemInform ◽  
2010 ◽  
Vol 26 (44) ◽  
pp. no-no
Author(s):  
S. HUNECK ◽  
U. HIMMELREICH ◽  
G. NICHOLSON
Keyword(s):  
Cyclic Depsipeptide

scholarly journals Total Synthesis of the Cyclic Depsipeptide Vioprolide D via its ( Z )‐Diastereoisomer

2020 ◽  
Vol 59 (30) ◽  
pp. 12357-12361
Author(s):  
Hanusch A. Grab ◽  
Volker C. Kirsch ◽  
Stephan A. Sieber ◽  
Thorsten Bach
Keyword(s):  
Total Synthesis ◽  
Cyclic Depsipeptide

Chemical and enzymatic stability of a cyclic depsipeptide, the novel, marine-derived, anti-cancer agent kahalalide F

2001 ◽  
Vol 12 (7) ◽  
pp. 575-582 ◽  
Author(s):  
Rolf W Sparidans ◽  
Ellen Stokvis ◽  
José M Jimeno ◽  
Luis López-Lázaro ◽  
Jan HM Schellens ◽  
...  
Keyword(s):  
The Novel ◽  
Enzymatic Stability ◽  
Cyclic Depsipeptide ◽  
Kahalalide F ◽  
Anti Cancer ◽  
Cancer Agent

X-ray and NMR Conformational Study of Aureobasidin E: A Cyclic Depsipeptide with Potent Antifungal Activity

1994 ◽  
Vol 59 (3) ◽  
pp. 570-578 ◽  
Author(s):  
Akihiko Fujikawa ◽  
Yasuko In ◽  
Masatoshi Inoue ◽  
Toshimasa Ishida ◽  
Nobuaki Nemoto ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Conformational Study ◽  
X Ray ◽  
Cyclic Depsipeptide

Sansalvamide: A new cytotoxic cyclic depsipeptide produced by a marine fungus of the genus Fusarium

1999 ◽  
Vol 40 (15) ◽  
pp. 2913-2916 ◽  
Author(s):  
Gilbert N Belofsky ◽  
Paul R Jensen ◽  
William Fenical
Keyword(s):  
Marine Fungus ◽  
Genus Fusarium ◽  
Cyclic Depsipeptide ◽  
Sansalvamide A
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