scholarly journals The occurrence of bound serine in acetone extracts of Serratia marcescens exclusively in compounds of a cyclic depsipeptide structure related to serratamolide

1970 ◽  
Vol 116 (4) ◽  
pp. 759-761 ◽  
Author(s):  
M A C Bermingham ◽  
B S Deol ◽  
J L Still
Leukemia ◽  
2005 ◽  
Vol 19 (4) ◽  
pp. 572-579 ◽  
Author(s):  
E Escobar-Díaz ◽  
E M López-Martín ◽  
M Hernández del Cerro ◽  
A Puig-Kroger ◽  
V Soto-Cerrato ◽  
...  

1970 ◽  
Vol 119 (5) ◽  
pp. 861-869 ◽  
Author(s):  
Margaret A. C. Bermingham ◽  
B. S. Deol ◽  
J. L. Still

The addition of low concentrations of streptomycin (5–10μg/ml of medium) to Serratia marcescens caused significant alterations in the lipid composition of this organism, but neither growth nor pigmentation was affected. The acetone-soluble cyclic depsipeptides, which comprise on average 15% of the total lipid, were decreased almost to zero and the total lipid phosphorus was more than doubled in the presence of streptomycin. Most of the phospholipid increase was due to an increase in phosphatidylethanolamine. Cyclic depsipeptides were not leached from the cell in the presence of streptomycin, indicating a definite inhibition of the biosynthetic pathway. The effect of streptomycin on the reported peptidolipids of Rhodopseudomonas spheroides, Halobacterium halobium, Nocardia asteroides and Pseudomonas tabaci was investigated. In the case of the only strictly comparable cellular cyclic depsipeptide (that of N. asteroides) the biosynthesis was strongly inhibited by streptomycin, but cell weight was maintained or even slightly increased. A possible mode and site of action of low concentrations of streptomycin on bacterial lipids is discussed.


1968 ◽  
Vol 121 (2) ◽  
pp. 145-150 ◽  
Author(s):  
W. H. Dodson
Keyword(s):  

Author(s):  
A. K. Veligodska ◽  
O. V. Fedotov ◽  
A. S. Petreeva

<p>The influence of certain nitrogen compounds - components of glucose-peptone medium (GPM) on the accumulation of carotenoids by some strains was investigated by surface cultivating basidiomycetes. The total carotenoid content was set in acetone extracts of mycological material spectrophotometrically and calculated using the Vetshteyn formula.</p> <p>As the nitrogen-containing components used GPM with 9 compounds, such as peptone, DL-valine, L-asparagine, DL-serine, DL-tyrosine, L-proline, L-alanine, urea, NaNO<sub>3</sub>. The effect on the accumulation of specific compounds both in the mycelium and in the culture fluid of carotenoids by culturing certain strains of Basidiomycetes was identified.</p> <p>Adding to standard glucose-peptone medium peptone at 5 g/l causes an increase of carotenoid accumulation by strain <em>L. sulphureus</em> Ls-08, and in a concentration of 4 g/l by strains of <em>F. hepatica </em>Fh-18 and <em>F. fomentarius</em> Ff-1201.</p> <p>In order to increase the accumulation of carotenoids in the mycelium  we suggested to make a standard glucose-peptone medium with proline or valine for cultivating of <em>L. sulphureus</em> Ls- 08 strain; alanine for <em>F. fomentarius</em> Ff-1201 strain; proline, asparagine and serine - for strain Fh-18 of <em>F. hepatica</em>. The results can be implemented in further optimization of the composition of the nutrient medium for culturing strains of Basidiomycetes wich producing carotenoids.</p> <p><em>Keywords: nitrogen-containing substances, Basidiomycetes, mycelium</em><em>,</em><em> culture filtrate, carotenoids</em></p>


2018 ◽  
Vol 7 (3) ◽  
pp. 108-109
Author(s):  
Javier Bustamante Odriozola ◽  
Álvaro Pérez Martín ◽  
Romina Verónica Quintana ◽  
María José Agüeros Fernández ◽  
Daniel Martínez Revuelta ◽  
...  
Keyword(s):  

Author(s):  
Renata Andreia dos Santos ◽  
Lucas Albuquerque Rosendo ◽  
Dayana Montero Rodríguez ◽  
Galba Maria de Campos Takaki ◽  
Marcos Antônio Barbosa de Lima
Keyword(s):  

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