Rational Design and Gas-Phase Characterization of Molecular Capsules by Self-Assembly of a Symmetric Hexasubstituted Benzene with Seven-Membered Lactams

2008 ◽  
Vol 130 (17) ◽  
pp. 5640-5641 ◽  
Author(s):  
Pierre Baillargeon ◽  
Yves L. Dory
2006 ◽  
Vol 90 (9) ◽  
pp. 3246-3254 ◽  
Author(s):  
Jonathan P. Williams ◽  
Daniel C. Smith ◽  
Brian N. Green ◽  
Brian D. Marsden ◽  
Keith R. Jennings ◽  
...  

2019 ◽  
Vol 21 (32) ◽  
pp. 17463-17474 ◽  
Author(s):  
Keisuke Hirata ◽  
Ryohei Tomihara ◽  
Kuenhee Kim ◽  
Kiichirou Koyasu ◽  
Tatsuya Tsukuda

This perspective summarizes our recent efforts in the application of gas-phase characterization methods to ligand-protected Au/Ag clusters chemically synthesized with atomic precision.


Author(s):  
Sjors Bakels ◽  
Sebastiaan Porskamp ◽  
Anouk Rijs

The spontaneous aggregation of proteins and peptides is widely studied due to its relation to neurodegenerative diseases. To understand the underlying principles of peptide aggregation, elucidation of structure and structural changes upon their formation is key. This level of detail can be obtained by studying the peptide self-assembly in the gas phase. Structural characterization of aggregates is mainly done on charged species, as adding charges is an intrinsic part of the technique to bring molecules into the gas phase. Studying neutral peptide aggregates will complement the existing picture. These studies are restricted to dimers due to experimental limitations. Here, we present advances in laser desorption molecular beam spectroscopy to form neutral peptide aggregates in the gas phase consisting of up to fourteen monomeric peptides. The combination with IR-UV spectroscopy allowed us to select each aggregate by size and subsequently characterize its structure.


2019 ◽  
Author(s):  
Sjors Bakels ◽  
Sebastiaan Porskamp ◽  
Anouk Rijs

The spontaneous aggregation of proteins and peptides is widely studied due to its relation to neurodegenerative diseases. To understand the underlying principles of peptide aggregation, elucidation of structure and structural changes upon their formation is key. This level of detail can be obtained by studying the peptide self-assembly in the gas phase. Structural characterization of aggregates is mainly done on charged species, as adding charges is an intrinsic part of the technique to bring molecules into the gas phase. Studying neutral peptide aggregates will complement the existing picture. These studies are restricted to dimers due to experimental limitations. Here, we present advances in laser desorption molecular beam spectroscopy to form neutral peptide aggregates in the gas phase consisting of up to fourteen monomeric peptides. The combination with IR-UV spectroscopy allowed us to select each aggregate by size and subsequently characterize its structure.


Author(s):  
Séverine Foucat ◽  
Thierry Pigot ◽  
Geneviève Pfister-Guillouzo ◽  
Stéphane Mazières ◽  
Hélène Lavayssière

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